13-05453. Leiopyrrole [Archived]

Nomenclature

CAS number: 5633-16-9
N,N-Diethyl-2-[2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy]ethanamine; 1-[o-(2-diethylaminoethoxy)phenyl]-2-methyl-5-phenylpyrrole; 2-methyl-1-(2-β-diethylaminoethoxyphenyl)-5-phenylpyrrole; DV-714.
C23H28N2O; mol wt 348.48.
C 79.27%, H 8.10%, N 8.04%, O 4.59%.

Description and references

Preparation: Buu-Hoi et al., J. Med. Pharm. Chem. 1, 23 (1959).

Chemical structure

Properties

Base, bp13 232°. nD20 1.6025.

Derivative

Hydrochloride.

Nomenclature

CAS number: 14435-78-0
Leioplegil (Diathera).
C23H28N2O.HCl; mol wt 384.94.
C 71.76%, H 7.59%, N 7.28%, O 4.16%, Cl 9.21%.

Properties

Needles from carbon tetrachloride, mp 138°. Readily sol in water; aq soln turns yellow on exposure to air or light.

Therapeutic Category

Antispasmodic.

Keywords

Antispasmodic

Status

This monograph has been retired and is no longer subject to revision or update.