13-05669. MADU [Archived]

Nomenclature

CAS number: 840-50-6
2′-Deoxy-5-(methylamino)uridine; 5-(methylamino)-2′-deoxyuridine.
C10H15N3O5; mol wt 257.24.
C 46.69%, H 5.88%, N 16.33%, O 31.10%.

Description and references

Prepn: Visser et al., Biochim. Biophys. Acta 76, 463 (1963). Active in vitro against herpes infections: Nemes, Hilleman, Proc. Soc. Exp. Biol. Med. 119, 515 (1965); Shen, US 3322627 (1967 to Merck & Co.).

Chemical structure

Properties

Crystals from ethanol + water, mp 180-182°.

Therapeutic Category

Antiviral.

Keywords

Antiviral; Purines/Pyrimidinones

Status

This monograph has been retired and is no longer subject to revision or update.