13-05856. Menazon [Archived]

Nomenclature

CAS number: 78-57-9
S-[(4,6-Diamino-1,3,5-triazin-2-yl)methyl]phosphorodithioic acid O,O-dimethyl ester; S-[(4,6-diamino-s-triazin-2-yl)methyl] O,O-dimethyl phosphorodithioate; O,O-dimethyl S-[(4,6-diamino-s-triazin-2-yl)methyl] phosphorodithioate; 2-dimethoxyphosphinothioylthiomethyl-4,6-diamino-s-triazine; ENT-25760; PP-175; Saphicol; Saphizon-DP; Sayfos (Chipman).
C6H12N5O2PS2; mol wt 281.30.
C 25.62%, H 4.30%, N 24.90%, O 11.38%, P 11.01%, S 22.80%.

Description and references

Prepn: Calderbank et al., DE 1118789 corresp to US 3169964 (1961, 1965 both to I.C.I.). Activity: eidem, Chem. Ind. (London) 1961, 630. Toxicity: T. B. Gaines, Toxicol. Appl. Pharmacol. 14, 515 (1969).

Chemical structure

Properties

Crystals, dec 160-162°, mp 164-166°. Vapor press. at 25°: 1×106 mm Hg. Low solubility in water and organic solvents. LD50 orally in male, female rats: 1020, 1450 mg/kg (Gaines).

Caution

Cholinesterase inhibitor.

Use

Insecticide; acaricide.

Status

This monograph has been retired and is no longer subject to revision or update.