13-06754. Novembichin [Archived]

Nomenclature

CAS number: 1936-40-9
2-Chloro-N,N-bis(2-chloroethyl)propanamine hydrochloride; 2-chloropropyldi(2-chloroethyl)amine hydrochloride; Novoembichin; Embichin 7; Embikhin 7.
C7H15Cl4N; mol wt 255.01.
C 32.97%, H 5.93%, Cl 55.61%, N 5.49%.

Description and references

Prepn: Ford-Moore et al., J. Chem. Soc. 1946, 819; E. Wilson, M. Tishler, J. Am. Chem. Soc. 73, 3635 (1951).

Chemical structure

Properties

Crystals from chloroform + ethanol, mp 78-79.4°.

Derivative

Free base.

Properties

Colorless oil, bp 114°.

Therapeutic Category

Antineoplastic.

Keywords

Antineoplastic; Alkylating Agents; Nitrogen Mustards

Status

This monograph has been retired and is no longer subject to revision or update.