13-06918. Ontianil [Archived]

Nomenclature

CAS number: 35727-72-1
N-(4-Chlorophenyl)-2,6-dioxocyclohexanecarbothioamide; 4′-chloro-2,6-dioxothiocyclohexanecarboxanilide.
C13H12ClNO2S; mol wt 281.76.
C 55.42%, H 4.29%, Cl 12.58%, N 4.97%, O 11.36%, S 11.38%.

Description and references

Prepn: H. Ruschig et al., DE 2039466; eidem, US 3746765 (1972, 1973 both to Hoechst); of sodium, potassium, calcium salts: eidem, DE 2317579 (1974 to Hoechst), C.A. 82, 64537f (1975).

Chemical structure

Properties

Crystals from ethanol, mp 113-115°. LD50 in rats (mg/kg): 964 s.c.; 229 i.v. (Ruschig, 1973).

Derivative

Potassium salt.

Nomenclature

Terondit (Hoechst).
C13H12ClKNO2S; mol wt 320.86.
C 48.66%, H 3.77%, Cl 11.05%, K 12.19%, N 4.37%, O 9.97%, S 9.99%.

Therapeutic Category (Veterinary)

Antifungal.

Status

This monograph has been retired and is no longer subject to revision or update.