13-07191. Pentamethonium Bromide [Archived]

Nomenclature

CAS number: 541-20-8
N,N,N,N′,N′,N′-Hexamethyl-1,5-pentanediaminium bromide; pentamethylenebis[trimethylammonium bromide]; α,ω-bis(trimethylammonium)pentane dibromide; 1,5-dibromohexamethylpentaneammonium; C-5; Penthonium; Lytensium.
C11H28Br2N2; mol wt 348.16.
C 37.95%, H 8.11%, Br 45.90%, N 8.05%.

Description and references

Ganglion blocking agent.

Chemical structure

Properties

Hygroscopic crystals, slight fishy odor, slightly bitter, saline taste. Aq solns are stable, almost neutral; can be sterilized by autoclaving. The compd is almost completely ionized in aq solns. It contains 54.10% of pentamethonium ion.

Therapeutic Category

Antihypertensive.

Keywords

Antihypertensive; Quaternary Ammonium Compounds

Status

This monograph has been retired and is no longer subject to revision or update.