Water for Chromatography

Deionised water with a resistivity of not less than 0.18 MΩ⋅m prepared by distillation, ion exchange, reverse osmosis or any other suitable method, using water that complies with the regulations on water intended for human consumption, as laid down by the competent authority.

Its quality is such that no significant interfering peaks or loss of sensitivity are observed when used in chromatography. Isocratic elution with UV detection at low wavelengths (i.e. less than 230 nm), with evaporative detectors (e.g. light scattering detector, particle counter detector, charged aerosol detector) or mass detectors, or gradient elution, may require the use of water with a total organic carbon content of maximum 5 ppb.