Ferrous Sulfate Tablets
Ferrous Sulphate Tablets
Definition
Ferrous Sulfate Tablets contain Dried Ferrous Sulfate. They are coated.
The tablets comply with the requirements stated under Tablets and with the following requirements.
Content of ferrous iron, Fe(ii)
95.0 to 105.0% of the stated amount.
Identification
A. The powdered tablets yield reaction A characteristic of iron salts, Appendix VI.
B. Extract the powdered tablets with 2m hydrochloric acid and filter. The filtrate yields reaction A characteristic of sulfates, Appendix VI.
Assay
Weigh and powder 20 tablets. Dissolve a quantity of the powder containing 0.5 g of dried ferrous sulfate as completely as possible in a mixture of 30 mL of water and 20 mL of 1m sulfuric acid and titrate with 0.1m ammonium cerium(iv) sulfate VS using ferroin solution as indicator. Each mL of 0.1m ammonium cerium(iv) sulfate VS is equivalent to 5.585 mg of Fe(ii).
Labelling
The quantity of active ingredient is stated both as the amount of dried ferrous sulfate and in terms of the equivalent amount of ferrous iron.