Soluble Sodium Chloride Tablets

Definition

Soluble Sodium Chloride Tablets contain Sodium Chloride.

Content of sodium chloride, NaCl

95.0 to 105.0% of the stated amount.

Identification

The powdered tablets yield the reactions characteristic of sodium salts and the reactions characteristic of chlorides, Appendix VI.

Tests

Clarity of solution

Dissolve a quantity of the tablets containing 0.6 g of Sodium Chloride in 100 mL of water. The solution is clear, Appendix IV A.

Disintegration

The tablets dissolve completely within 15 minutes when examined by the disintegration test for tablets and capsules, Appendix XII A1, but using water at 19° to 21°.

Assay

Weigh and powder 20 tablets. Dissolve a quantity of the powder containing 0.2 g of Sodium Chloride in 35 mL of water, add 15 mL of 2m nitric acid, 5 mL of dibutyl phthalate and 50 mL of 0.1m silver nitrate VS and shake vigorously for about 1 minute. Add 5 mL of ammonium iron(iii) sulfate solution R2 and titrate with 0.1m ammonium thiocyanate VS until a reddish brown colour is obtained which, after shaking, does not fade within 5 minutes. Each mL of 0.1m silver nitrate VS is equivalent to 5.844 mg of NaCl.