SC V E. Extemporaneous Preparations

This section provides information and guidance on well-established formulae for widely used unlicensed medicines.

This section includes examples of well-established formulae and/or methods that may be used to prepare a medicinal product extemporaneously. Formulae other than those specified in this section may also be available and the medicinal product may be prepared by other means.

An article intended for medicinal use that is described by means of an official title must comply with the requirements of the relevant monograph, regardless of how it is prepared.

The examples provided have been taken from former fixed strength monographs of the British Pharmacopoeia. These monographs have been amended to an open strength format in order to allow a single monograph to apply to the range of strengths available.

Dithranol Paste

Extemporaneous preparation

Mix the Dithranol with a portion of the Zinc and Salicylic Acid Paste until a smooth, even dispersion is obtained and gradually incorporate the remainder of the Zinc and Salicylic Acid Paste.

Levomenthol Cream

Extemporaneous preparation

Grind the Levomenthol to a fine powder. If necessary, a small amount of Glycerol may be added to minimise the creation of airborne menthol dust. Add the Aqueous Cream gradually and mix until smooth.

Salicylic Acid Ointment

Extemporaneous preparation

Melt the Wool Alcohols Ointment, gradually add the Salicylic Acid and stir until cold.