ID
DB00181|APRD00551||
名称
Baclofen
描述
Baclofen is a gamma-aminobutyric acid (GABA) agonist used as a skeletal muscle relaxant used for the relief of painful and uncomfortable muscle spasms caused by a variety of conditions. It is known to be particularly useful in treating muscle spasticity associated with spinal cord injury [FDA label]. This drug has recently been studied for the management of alcohol withdrawal, however, a conclusion has not been made regarding baclofen efficacy in this condition [A173908], [A173911], [A173938]. This drug was initially approved by the FDA in 1992 [F4570]. It is available in tablet form [FDA label], injection form [F4570], and powder form (for suspension) [L6130].
cas号
1134-47-0
唯一标识码
H789N3FKE8
状态
solid
一般参考文献
Dzitoyeva S, Dimitrijevic N, Manev H: Gamma-aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5485-90. Epub 2003 Apr 11.
Mezler M, Muller T, Raming K: Cloning and functional expression of GABA(B) receptors from Drosophila. Eur J Neurosci. 2001 Feb;13(3):477-86.
See S, Ginzburg R: Skeletal muscle relaxants. Pharmacotherapy. 2008 Feb;28(2):207-13. doi: 10.1592/phco.28.2.207.
Brennan JL, Leung JG, Gagliardi JP, Rivelli SK, Muzyk AJ: Clinical effectiveness of baclofen for the treatment of alcohol dependence: a review. Clin Pharmacol. 2013 Jul 3;5:99-107. doi: 10.2147/CPAA.S32434. Print 2013.
Liu J, Wang LN: Baclofen for alcohol withdrawal. Cochrane Database Syst Rev. 2017 Aug 20;8:CD008502. doi: 10.1002/14651858.CD008502.pub5.
Liu J, Wang LN: Baclofen for alcohol withdrawal. Cochrane Database Syst Rev. 2013 Feb 28;(2):CD008502. doi: 10.1002/14651858.CD008502.pub3.
Dario A, Tomei G: A benefit-risk assessment of baclofen in severe spinal spasticity. Drug Saf. 2004;27(11):799-818. doi: 10.2165/00002018-200427110-00004.
Finnimore AJ, Roebuck M, Sajkov D, McEvoy RD: The effects of the GABA agonist, baclofen, on sleep and breathing. Eur Respir J. 1995 Feb;8(2):230-4.
Chen K, Li HZ, Ye N, Zhang J, Wang JJ: Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro. Brain Res Bull. 2005 Oct 30;67(4):310-8. doi: 10.1016/j.brainresbull.2005.07.004.
Fu Z, Yang H, Xiao Y, Zhao G, Huang H: The gamma-aminobutyric acid type B (GABAB) receptor agonist baclofen inhibits morphine sensitization by decreasing the dopamine level in rat nucleus accumbens. Behav Brain Funct. 2012 Jul 10;8:20. doi: 10.1186/1744-9081-8-20.
Di Ciano P, Everitt BJ: The GABA(B) receptor agonist baclofen attenuates cocaine- and heroin-seeking behavior by rats. Neuropsychopharmacology. 2003 Mar;28(3):510-8. doi: 10.1038/sj.npp.1300088. Epub 2002 Oct 14.
de Beaurepaire R: A Review of the Potential Mechanisms of Action of Baclofen in Alcohol Use Disorder. Front Psychiatry. 2018 Oct 17;9:506. doi: 10.3389/fpsyt.2018.00506. eCollection 2018.
Hara T, Nakajima M, Sugano H, Karagiozov K, Hirose E, Goto K, Arai H: Pregnancy and Breastfeeding during Intrathecal Baclofen Therapy - A Case Study and Review. NMC Case Rep J. 2018 Jun 25;5(3):65-68. doi: 10.2176/nmccrj.cr.2017-0191. eCollection 2018 Jul.

Baclofen tablets
https://www.medicines.org.uk/emc/product/5728/smpc
Baclofen powder, DailyMed
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0a32d8e8-a89a-40c1-8889-b3de5a2d839e
Pacifen Medsafe NZ
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Lioresal (intrathecal) FDA label
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Gablofen (Baclofen injection) FDA label
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F2980Pacifen Medsafe NZ//s3-us-west-2.amazonaws.com/drugbank/cite_this/attachments/files/000/002/980/original/Medsafe_NZ-_Pacifen.pdf?1547763088F2983Lioresal (intrathecal) FDA label//s3-us-west-2.amazonaws.com/drugbank/cite_this/attachments/files/000/002/983/original/Lioresal_Intrathecal_.pdf?1547768190F4570Gablofen (Baclofen injection) FDA label//s3-us-west-2.amazonaws.com/drugbank/cite_this/attachments/files/000/004/570/original/Gablofen_%28baclofen_injection%29_FDA_label.pdf?1556651498
approved,
指示
Baclofen is administered for the relief of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and associated pain and clonus, in addition to muscular rigidity [FDA label]. Patients receiving this drug should have reversible spasticity for baclofen to promote the restoration of residual function. This drug is not indicated in the treatment of skeletal muscle spasm caused by rheumatic disorders. The efficacy of baclofen in stroke, cerebral palsy, and Parkinson's disease has not been determined and, therefore, baclofen is not recommended for these conditions [FDA label].
药效学
In neurological diseases associated with spasm of the skeletal muscles, the clinical effects of baclofen occur due to baclofen action on reflex muscle contractions and of significant relief from painful spasm, automatism, as well as clonus. Baclofen, when used as indicated, improves mobility, increasing levels of independence, and facilitates both passive and active physiotherapy. Baclofen also stimulates gastric acid secretion [F2980]. GABA-B receptor activation by baclofen may produce protective neurological effects. Baclofen also possesses anti-inflammatory properties that may be of interest in the study of addiction treatment [A173938]. Preclinical studies have shown that GABA-B receptors have roles in memory storage and retrieval, reward, motivation, mood, as well as anxiety. Neuroimaging studies in humans indicate that baclofen produces region-specific alterations in brain activity.
作用机制
The exact mechanism of action of baclofen is not fully understood at this time [FDA label], [F2983]. Many studies indicate that baclofen is a GABA-B receptor agonist [A254], [A25184], [A173923], [A173926], [A173929]. Despite this, there is no conclusive evidence that the effects of baclofen on GABA systems are involved in the production of its clinical effects [FDA label]. Baclofen is an effective and widely used antispastic agent with a spinal site of action. Its mechanism of action and pharmacological properties are different from the effects of other antispastic agents. In addition, baclofen has central sites of action, shown by its adverse event profile and general CNS depressant properties [F2980]. GABA-B receptors interact with signal transduction pathways and neurotransmitter systems. Baclofen exerts an antinociceptive effect. The clinical significance of this warrants further research data for clarification. Baclofen depresses monosynaptic and polysynaptic reflex transmission, by various actions, and possibly including the stimulation of GABAβ-receptors. This stimulation results in the inhibition of excitatory neurotransmitter (glutamate and aspartate) release, which may normally contribute to pain and spasticity[F2980]. Although baclofen is an analog of the inhibitory neurotransmitter gamma-amino-butyric acid (GABA), there are no conclusive data indicating GABA systems are involved in its clinical effects [FDA label].
毒性
LD50 after oral administration in rats: 145 mg/kg [MSDS] **Overdosage**: Vomiting, muscular hypotonia, drowsiness, accommodation disorders, coma, respiratory depression, and seizures may occur with overdosage [FDA label]. **Pregnancy**: This drug is a pregnancy category C drug. There are no adequate and well-controlled studies that have been performed with pregnant women. Baclofen should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus [FDA label]. **Excretion in breastmilk**: It is unknown whether this drug is excreted in human breast milk. Because many drugs are excreted in human milk, caution is warranted when baclofen is administered to a nursing woman [FDA label].
代谢
Approximately 15% of the dose is metabolized in the liver, mainly by deamination [FDA label]. In a clinical study with radiolabeled baclofen, approximately 85% of the dose was excreted unchanged in the urine and feces. The γ-hydroxy metabolite, 3-(p-chlorophenyl)-4-hydroxybutyric acid, is formed by the deamination of baclofen [FDA label]. Because baclofen is partially metabolized in the liver, patients with impaired liver function should be regularly monitored with liver function tests [F2980].
吸收
Rapidly and almost completely absorbed from the gastrointestinal tract. Absorption may be dose-dependent, being reduced with increased doses [FDA label]. Baclofen, when introduced directly into the intrathecal space, allows for effective CSF concentrations to be achieved with resulting plasma concentrations 100 times less than concentrations occurring with oral administration [F2983], [FDA label].
半衰期
Elimination half-life: Approximately 5.5 hours [FDA label].
分类
description:This compound belongs to the class of organic compounds known as gamma amino acids and derivatives. These are amino acids having a (-NH2) group attached to the gamma carbon atom.
direct-parent:Gamma amino acids and derivatives
kingdom:Organic compounds
superclass:Organic acids and derivatives
class:Carboxylic acids and derivatives
subclass:Amino acids, peptides, and analogues
alternative-parent:Amino acids
alternative-parent:Amino fatty acids
alternative-parent:Aralkylamines
alternative-parent:Aryl chlorides
alternative-parent:Carbonyl compounds
alternative-parent:Carboxylic acids
alternative-parent:Chlorobenzenes
alternative-parent:Hydrocarbon derivatives
alternative-parent:Monoalkylamines
alternative-parent:Monocarboxylic acids and derivatives
alternative-parent:Organic oxides
alternative-parent:Organochlorides
alternative-parent:Organopnictogen compounds
alternative-parent:Phenylpropanoic acids
substituent:3-phenylpropanoic-acid
substituent:Amine
substituent:Amino acid
substituent:Amino fatty acid
substituent:Aralkylamine
substituent:Aromatic homomonocyclic compound
substituent:Aryl chloride
substituent:Aryl halide
substituent:Benzenoid
substituent:Carbonyl group
substituent:Carboxylic acid
substituent:Chlorobenzene
substituent:Fatty acyl
substituent:Gamma amino acid or derivatives
substituent:Halobenzene
substituent:Hydrocarbon derivative
substituent:Monocarboxylic acid or derivatives
substituent:Monocyclic benzene moiety
substituent:Organic nitrogen compound
substituent:Organic oxide
substituent:Organic oxygen compound
substituent:Organochloride
substituent:Organohalogen compound
substituent:Organonitrogen compound
substituent:Organooxygen compound
substituent:Organopnictogen compound
substituent:Primary aliphatic amine
substituent:Primary amine
消除途径
Baclofen is rapidly and extensively eliminated from the body. There is significant intersubject variation in elimination rates. Baclofen is excreted mainly by the kidney as unchanged drug. Seventy to eighty (70 - 80%) of a dose is measured in the urine as unchanged drug. The remainder of the dose is excreted as unchanged drug in the feces or as metabolites in the urine and feces. Excretion is complete within 72 hours after administration [FDA label].
种类
Agents Causing Muscle Toxicity

Amino Acids
D000596
Amino Acids, Peptides, and Proteins
D000602
Aminobutyrates
D000613
Butyrates
D002087
Central Nervous System Agents
D002491
Central Nervous System Depressants
D002492
Drugs that are Mainly Renally Excreted

GABA Agents
D018682
GABA Agonists
D018755
GABA-B Receptor Agonists
D058786
Gaba-derivative Skeletal Muscle Relaxants

gamma-Aminobutyric Acid-ergic Agonist

Muscle Relaxants

Muscle Relaxants, Centrally Acting Agents
D009125
Muscle Relaxants, Peripherally Acting Agents

Musculo-Skeletal System

Neurotransmitter Agents
D018377
盐类
DBSALT002256Baclofen hydrochloride64OSE3996V28311-31-1WMNUVYYLMCMHLU-UHFFFAOYSA-N250.12249.0323341
蛋白质结合
30% [FDA label]
清除
**Total systemic clearance**: 180 mL/min [FDA label] **Renal clearance**: 103 mL/min [FDA label] Baclofen is primarily excreted unchanged by the kidneys. It should be administered cautiously, and it may be necessary to reduce the dosage in patients with reduced renal function [FDA label].
同义词
language:english; code:; name;(+-)-Baclofen
language:english; code:; name;4-Amino-3-(4-chlorophenyl)butyric acid
language:english; code:inn/usan; name;Baclofen
language:french; code:; name;Baclofène
language:spanish; code:inn; name;Baclofeno
language:latin; code:inn; name;Baclofenum
language:english; code:; name;beta-(4-Chlorophenyl)gaba
language:english; code:; name;beta-(Aminomethyl)-4-chlorobenzenepropanoic acid
language:english; code:; name;beta-(Aminomethyl)-p-chlorohydrocinnamic acid
language:english; code:; name;beta-(p-Chlorophenyl)-gamma-aminobutyric acid
language:english; code:; name;DL-4-Amino-3-p-chlorophenylbutanoic acid
language:english; code:; name;DL-Baclofen
language:english; code:; name;gamma-Amino-beta-(p-chlorophenyl)butyric acid
国际品牌
BaclonUniao Quimica (Brazil)Lioresal IntrathecalNovartis PharmaceuticalsNu-BaclofenNu-Pharm
配送量
**Apparent volume of distribution**: 59 liters [FDA label]. Baclofen does not readily cross the blood-brain barrier [FDA label].
产品
name:Apo-baclofen
labeller:Apotex Corporation
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labeller:Med Pharma Co., Ltd.
ndc-id:
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country:US
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over-the-counter:false
approved:true
country:Canada
source:DPD
name:Riva-baclofen
labeller:Laboratoire Riva Inc
ndc-id:
ndc-product-code:
dpd-id:02242151
ema-product-code:
ema-ma-number:
started-marketing-on:2003-03-03
ended-marketing-on:
dosage-form:Tablet
strength:
route:Oral
fda-application-number:
generic:true
over-the-counter:false
approved:true
country:Canada
source:DPD
name:Sandoz Baclofen
labeller:Sandoz Canada Incorporated
ndc-id:
ndc-product-code:
dpd-id:02442140
ema-product-code:
ema-ma-number:
started-marketing-on:
ended-marketing-on:
dosage-form:Tablet
strength:
route:Oral
fda-application-number:
generic:true
over-the-counter:false
approved:true
country:Canada
source:DPD
name:Sandoz Baclofen
labeller:Sandoz Canada Incorporated
ndc-id:
ndc-product-code:
dpd-id:02442159
ema-product-code:
ema-ma-number:
started-marketing-on:
ended-marketing-on:
dosage-form:Tablet
strength:
route:Oral
fda-application-number:
generic:true
over-the-counter:false
approved:true
country:Canada
source:DPD
混合物
name:Kemstro
ingredients:Baclofen
name:Kemstro
ingredients:Baclofen
name:Bacolfen
ingredients:Baclofen
name:Bacolfen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Innoprax-5
ingredients:Amantadine + Baclofen + Diclofenac + Gabapentin + Lidocaine
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Lioresal
ingredients:Baclofen
name:Lioresal
ingredients:Baclofen
name:Lioresal
ingredients:Baclofen
name:Lioresal
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Gablofen
ingredients:Baclofen
name:Gablofen
ingredients:Baclofen
name:Gablofen
ingredients:Baclofen
name:Gablofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Equipto - Baclofen External Cream Compounding Kit
ingredients:Baclofen
name:Gapeam Budibac
ingredients:Amantadine + Baclofen + Bupivacaine + Cyclobenzaprine + Diclofenac + Gabapentin + Pentoxifylline
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen (intrathecal)
ingredients:Baclofen
name:Baclofen (intrathecal)
ingredients:Baclofen
name:Baclofen (intrathecal)
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Lioresal (baclofen)
ingredients:Baclofen
name:Lioresal (baclofen)
ingredients:Baclofen
name:Lioresal (baclofen)
ingredients:Baclofen
name:Lioresal (baclofen)
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen (Intrathecal)
ingredients:Baclofen
name:Baclofen (Intrathecal)
ingredients:Baclofen
name:Ozobax
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Gablofen
ingredients:Baclofen
name:Gablofen
ingredients:Baclofen
name:Gablofen
ingredients:Baclofen
name:Gablofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Lioresal
ingredients:Baclofen
name:Lioresal
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Mylan-baclofen
ingredients:Baclofen
name:Mylan-baclofen
ingredients:Baclofen
name:Apo-baclofen
ingredients:Baclofen
name:Apo-baclofen
ingredients:Baclofen
name:Lioresal Intrathecal 2mg/ml
ingredients:Baclofen
name:Lioresal Intrathecal 0.05mg/ml
ingredients:Baclofen
name:Lioresal Intrathecal 0.5mg/ml
ingredients:Baclofen
name:Baclofen-10
ingredients:Baclofen
name:Baclofen-20
ingredients:Baclofen
name:Lioresal Tab 10mg
ingredients:Baclofen
name:Ratio-baclofen
ingredients:Baclofen
name:Ratio-baclofen
ingredients:Baclofen
name:Lioresal D.S. Tab 20mg
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Med Baclofen Tab 10mg
ingredients:Baclofen
name:Med Baclofen Tab 20mg
ingredients:Baclofen
name:Baclofen Tablets - 20mg
ingredients:Baclofen
name:Baclofen Tablets - 10mg
ingredients:Baclofen
name:Baclofen Tablets 10mg
ingredients:Baclofen
name:Baclofen Tablets 20mg
ingredients:Baclofen
name:Ftp-baclofen
ingredients:Baclofen
name:Ftp-baclofen
ingredients:Baclofen
name:Ava-baclofen
ingredients:Baclofen
name:Ava-baclofen
ingredients:Baclofen
name:Sandoz Baclofen
ingredients:Baclofen
name:Sandoz Baclofen
ingredients:Baclofen
name:Novo-baclofen
ingredients:Baclofen
name:Novo-baclofen
ingredients:Baclofen
name:PMS-baclofen
ingredients:Baclofen
name:PMS-baclofen Tab 20mg
ingredients:Baclofen
name:Riva-baclofen
ingredients:Baclofen
name:Riva-baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Baclofen
ingredients:Baclofen
name:Dom-baclofen-tab 20mg
ingredients:Baclofen
name:Dom-baclofen-tab 10mg
ingredients:Baclofen
name:Baclofen Injection
ingredients:Baclofen
name:Baclofen Injection
ingredients:Baclofen
name:Baclofen Injection
ingredients:Baclofen
name:PHL-baclofen
ingredients:Baclofen
name:PHL-baclofen
ingredients:Baclofen
name:Co Baclofen Tablets 10mg
ingredients:Baclofen
name:Co Baclofen Tablets 20mg
ingredients:Baclofen
name:Baclofen Injection
ingredients:Baclofen
name:Baclofen Injection
ingredients:Baclofen
name:Baclofen Injection
ingredients:Baclofen
name:Penta-baclofen Tablets
ingredients:Baclofen
name:Penta-baclofen Tablets
ingredients:Baclofen
name:Baclofen Intrathecal
ingredients:Baclofen
name:Baclofen Intrathecal
ingredients:Baclofen
name:Baclofen Intrathecal
ingredients:Baclofen
包装者
name:Actavis Group
url:http://www.actavis.com
name:Advanced Pharmaceutical Services Inc.
url:
name:Aidarex Pharmacuticals LLC
url:http://www.aidarex.com
name:Alphapharm Party Ltd.
url:http://www.alphapharm.com.au
name:Amerisource Health Services Corp.
url:http://www.amerisourcebergen.com
name:Apotheca Inc.
url:
name:A-S Medication Solutions LLC
url:http://orders.a-smeds.com
name:Bryant Ranch Prepack
url:http://bryantranchprepack.com
name:Caraco Pharmaceutical Labs
url:http://www.caraco.com
name:Cardinal Health
url:http://www.cardinal.com
name:Caremark LLC
url:http://www.caremark.com
name:Comprehensive Consultant Services Inc.
url:
name:Corepharma LLC
url:http://www.corepharma.com
name:Direct Dispensing Inc.
url:
name:Dispensing Solutions
url:http://www.drxdispensing.com
name:Diversified Healthcare Services Inc.
url:http://www.dhscorp.com
name:Genpharm LP
url:
name:Heartland Repack Services LLC
url:
name:Innoviant Pharmacy Inc.
url:http://www.innoviantpharmacy.com
name:Ivax Pharmaceuticals
url:
name:Keltman Pharmaceuticals Inc.
url:http://www.keltman.com
name:Lake Erie Medical and Surgical Supply
url:
name:Lannett Co. Inc.
url:http://www.lannett.com
name:Major Pharmaceuticals
url:http://www.majorpharmaceuticals.com
name:Mckesson Corp.
url:http://www.mckesson.com
name:Medisca Inc.
url:http://www.medisca.com
name:Medtronic
url:http://www.medtronic.com
name:Murfreesboro Pharmaceutical Nursing Supply
url:http://www.unitdosesupply.com
name:Mylan
url:http://www.mylan.com
name:Northstar Rx LLC
url:
name:Novartis AG
url:http://www.novartis.com
name:Nucare Pharmaceuticals Inc.
url:http://www.nucarerx.com
name:Palmetto Pharmaceuticals Inc.
url:http://www.palmettopharm.com
name:PD-Rx Pharmaceuticals Inc.
url:http://www.pdrx.com
name:Pharmaceutical Packaging Center
url:
name:Physicians Total Care Inc.
url:http://www.physicianstotalcare.com
name:Piramal Healthcare
url:http://www.piramalpharmasolutions.com
name:Preferred Pharmaceuticals Inc.
url:http://www.preferredpharmaceuticals.com
name:Prepak Systems Inc.
url:http://www.prepaksys.com
name:Prescription Dispensing Service Inc.
url:
name:Qualitest
url:http://www.worldoftest.com
name:Rebel Distributors Corp.
url:http://www.rebelrx.com
name:Remedy Repack
url:http://www.remedyrepack.com
name:Resource Optimization and Innovation LLC
url:
name:Sandhills Packaging Inc.
url:http://www.sandhillspackaging.com
name:Southwood Pharmaceuticals
url:http://www.southwoodhealthcare.com
name:St Mary's Medical Park Pharmacy
url:
name:Stat Rx Usa
url:http://statrxusa.exporterus.com
name:UDL Laboratories
url:http://www.udllabs.com
name:United Research Laboratories Inc.
url:http://www.urlpharma.com
name:USL Pharma Inc.
url:
name:Vangard Labs Inc.
url:
name:Vintage Pharmaceuticals Inc.
url:
name:Watson Pharmaceuticals
url:http://www.watson.com
生产者
generic:否; url:; name;Medtronic inc
generic:否; url:; name;Schwarz pharma inc
generic:是; url:; name;Actavis totowa llc
generic:是; url:; name;Caraco pharmaceutical laboratories ltd
generic:是; url:; name;Impax laboratories inc
generic:是; url:; name;Ivax pharmaceuticals inc sub teva pharmaceuticals usa
generic:是; url:; name;Lannett holdings inc
generic:是; url:; name;Matrix laboratories ltd
generic:是; url:; name;Mylan pharmaceuticals inc
generic:是; url:; name;Northstar healthcare holdings ltd
generic:是; url:; name;Teva pharmaceuticals usa inc
generic:是; url:; name;Usl pharma inc
generic:是; url:; name;Vintage pharmaceuticals inc
generic:是; url:; name;Watson laboratories inc
generic:否; url:; name;Novartis pharmaceuticals corp
价格
Lioresal D.S. 20 mg Tablet
1.4(单位:USD)
tablet
Lioresal Intrathecal 0.5 mg/ml
11.16(单位:USD)
ml
Lioresal it 10 mg/20 ml kit
12.9(单位:USD)
ml
Baclofen powder
14.38(单位:USD)
g
Lioresal Intrathecal 0.05 mg/ml
14.89(单位:USD)
ml
Lioresal Intrathecal 2 mg/ml
44.64(单位:USD)
ml
Lioresal it 10 mg/5 ml kit
51.6(单位:USD)
ml
Lioresal it 0.05 mg/1 ml amp
84.0(单位:USD)
ml
Apo-Baclofen 10 mg Tablet
0.3(单位:USD)
tablet
Mylan-Baclofen 10 mg Tablet
0.3(单位:USD)
tablet
Nu-Baclo 10 mg Tablet
0.3(单位:USD)
tablet
Phl-Baclofen 10 mg Tablet
0.3(单位:USD)
tablet
Pms-Baclofen 10 mg Tablet
0.3(单位:USD)
tablet
Ratio-Baclofen 10 mg Tablet
0.3(单位:USD)
tablet
Baclofen 10 mg tablet
0.51(单位:USD)
tablet
Apo-Baclofen 20 mg Tablet
0.59(单位:USD)
tablet
Mylan-Baclofen 20 mg Tablet
0.59(单位:USD)
tablet
Nu-Baclo 20 mg Tablet
0.59(单位:USD)
tablet
Phl-Baclofen 20 mg Tablet
0.59(单位:USD)
tablet
Pms-Baclofen 20 mg Tablet
0.59(单位:USD)
tablet
Ratio-Baclofen 20 mg Tablet
0.59(单位:USD)
tablet
Lioresal 10 mg Tablet
0.72(单位:USD)
tablet
Baclofen 20 mg tablet
0.92(单位:USD)
tablet
受影响的生物体
Humans and other mammals
剂量
form:Injection, solution
route:Intrathecal
strength:10 mg/20mL
form:Injection, solution
route:Intrathecal
strength:1000 ug/1mL
form:Injection, solution
route:Intrathecal
strength:40 mg/20mL
form:Suspension
route:Oral
strength:2 mg/1mL
form:Tablet
route:Oral
strength:20 mg
form:Tablet
route:Oral
strength:5 mg/1
form:Injection
route:Intrathecal
strength:10 mg/20mL
form:Injection
route:Intrathecal
strength:40 mg/20mL
form:Solution
route:Intrathecal
strength:0.05 mg
form:Solution
route:Intrathecal
strength:40 mg
form:Tablet
route:Oral
strength:25 MG
form:Tablet
route:Oral
strength:10 MG
form:Injection, solution
route:Intrathecal
strength:0.05 mg/ml
form:Injection, solution
route:Intrathecal
strength:0.5 mg/ml
form:Injection, solution
route:Intrathecal
strength:2 mg/ml
form:Injection, solution
route:Parenteral
strength:0.05 mg/ml
form:Solution
route:Parenteral
strength:0.5 mg/ml
form:Solution
route:Parenteral
strength:2 mg/ml
form:Injection, solution
route:
strength:0.05 MG/ML
form:Injection, solution
route:
strength:0.5 MG/ML
form:Injection, solution
route:
strength:1 MG/ML
form:Injection, solution
route:
strength:2 MG/ML
form:Injection, solution
route:
strength:0.05 MG/1ML
form:Injection, solution
route:
strength:10 MG/5ML
form:Injection, solution
route:
strength:10 MG/20ML
form:Tablet
route:Oral
strength:10 mg/1
form:Tablet
route:Oral
strength:20 mg/1
form:Solution
route:Intrathecal
strength:10 mg
form:Kit
route:Topical
strength:1 g/1g
form:Injection
route:Intrathecal
strength:1000 ug/1mL
form:Injection
route:Intrathecal
strength:2000 ug/1mL
form:Injection
route:Intrathecal
strength:50 ug/1mL
form:Injection
route:Intrathecal
strength:500 ug/1mL
form:Injection, solution
route:Intrathecal
strength:2000 ug/1mL
form:Injection, solution
route:Intrathecal
strength:50 ug/1mL
form:Injection, solution
route:Intrathecal
strength:500 ug/1mL
form:Kit
route:Topical
strength:
form:Tablet, orally disintegrating
route:Oral
strength:10 mg/1
form:Tablet, orally disintegrating
route:Oral
strength:20 mg/1
form:Injection
route:Intrathecal
strength:0.05 mg/1mL
form:Injection
route:Intrathecal
strength:0.5 mg/1mL
form:Injection
route:Intrathecal
strength:2 mg/1mL
form:Injection, solution
route:Intrathecal
strength:0.05 MG/1ML
form:Injection, solution
route:Intrathecal
strength:10 MG/5ML
form:Injection
route:Intrathecal
strength:10 mg/5mL
form:Tablet
route:Oral
strength:5 mg
form:Solution
route:Intrathecal
strength:
form:Solution
route:Intrathecal
strength:0.05 mg/1ml
form:Solution
route:Intrathecal
strength:10 mg/20ml
form:Solution
route:Intrathecal
strength:10 mg/5ml
form:Tablet
route:Oral
strength:
form:Solution
route:Oral
strength:5 mg/5mL
atc代码
Other centrally acting agents
MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
MUSCLE RELAXANTS
MUSCULO-SKELETAL SYSTEM
fda标签
//s3-us-west-2.amazonaws.com/drugbank/fda_labels/DB00181.pdf?1265922800
化学品安全技术说明书
//s3-us-west-2.amazonaws.com/drugbank/msds/DB00181.pdf?1265922739
专利
number:6221392
country:United States
approved:2001-04-24
expires:2018-04-09
pediatric-extension:否
number:6024981
country:United States
approved:2000-02-15
expires:2018-04-09
pediatric-extension:否
number:10610502
country:United States
approved:2019-08-30
expires:2039-08-30
pediatric-extension:否
食物相互作用
Avoid alcohol.Take with food. Take with food or milk to reduce gastric irritation.
药物相互作用
DB00921
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Buprenorphine.
DB00366
Doxylamine may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB00470
Dronabinol may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB00450
Droperidol may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB00956
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Hydrocodone.
DB00557
Hydroxyzine may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB00653
The therapeutic efficacy of Baclofen can be increased when used in combination with Magnesium sulfate.
DB01403
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Methotrimeprazine.
DB01017
Minocycline may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB00370
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Mirtazapine.
DB00486
Nabilone may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB01173
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Orphenadrine.
DB09117
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Paraldehyde.
DB08883
Perampanel may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB00413
Baclofen may increase the sedative activities of Pramipexole.
DB00268
Baclofen may increase the sedative activities of Ropinirole.
DB05271
Baclofen may increase the sedative activities of Rotigotine.
DB06201
The risk or severity of adverse effects can be increased when Rufinamide is combined with Baclofen.
DB09072
Sodium oxybate may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB09034
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Suvorexant.
DB06204
Tapentadol may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB01041
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.
DB00425
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Zolpidem.
DB00333
The risk or severity of adverse effects can be increased when Methadone is combined with Baclofen.
DB00898
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Ethanol.
DB00972
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
DB00484
Brimonidine may increase the central nervous system depressant (CNS depressant) activities of Baclofen.
DB09236
Baclofen may increase the hypotensive activities of Lacidipine.
DB00176
The risk or severity of adverse effects can be increased when Baclofen is combined with Fluvoxamine.
DB00215
The risk or severity of adverse effects can be increased when Baclofen is combined with Citalopram.
DB00476
The risk or severity of adverse effects can be increased when Baclofen is combined with Duloxetine.
DB00656
The risk or severity of adverse effects can be increased when Baclofen is combined with Trazodone.
DB00715
The risk or severity of adverse effects can be increased when Baclofen is combined with Paroxetine.
DB01104
The risk or severity of adverse effects can be increased when Baclofen is combined with Sertraline.
DB01105
The risk or severity of adverse effects can be increased when Baclofen is combined with Sibutramine.
DB01149
The risk or severity of adverse effects can be increased when Baclofen is combined with Nefazodone.
DB01175
The risk or severity of adverse effects can be increased when Baclofen is combined with Escitalopram.
DB04832
The risk or severity of adverse effects can be increased when Baclofen is combined with Zimelidine.
DB04884
The risk or severity of adverse effects can be increased when Baclofen is combined with Dapoxetine.
DB04896
The risk or severity of adverse effects can be increased when Baclofen is combined with Milnacipran.
DB06700
The risk or severity of adverse effects can be increased when Baclofen is combined with Desvenlafaxine.
DB06731
The risk or severity of adverse effects can be increased when Baclofen is combined with Seproxetine.
DB08918
The risk or severity of adverse effects can be increased when Baclofen is combined with Levomilnacipran.
DB08953
The risk or severity of adverse effects can be increased when Baclofen is combined with Indalpine.
DB12693
The risk or severity of adverse effects can be increased when Baclofen is combined with Ritanserin.
DB13233
The risk or severity of adverse effects can be increased when Baclofen is combined with Alaproclate.
DB00209
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Trospium.
DB00219
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Oxyphenonium.
DB00245
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Benzatropine.
DB00332
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Ipratropium.
DB00340
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Metixene.
DB00342
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Terfenadine.
DB00354
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Buclizine.
DB00376
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Trihexyphenidyl.
DB00383
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Oxyphencyclimine.
DB00387
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Procyclidine.
DB00392
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Profenamine.
DB00424
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Hyoscyamine.
DB00434
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Cyproheptadine.
DB00462
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Methscopolamine bromide.
DB00496
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Darifenacin.
DB00505
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Tridihexethyl.
DB00517
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Anisotropine methylbromide.
DB00572
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Atropine.
DB00670
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Pirenzepine.
DB00725
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Homatropine methylbromide.
DB00767
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Benzquinamide.
DB00777
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Propiomazine.
DB00782
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Propantheline.
DB00804
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Dicyclomine.
DB00810
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Biperiden.
DB00907
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Cocaine.
DB00934
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Maprotiline.
DB00940
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Methantheline.
DB00942
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Cycrimine.
DB00986
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Glycopyrronium.
DB01036
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Tolterodine.
DB01062
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Oxybutynin.
DB01148
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Flavoxate.
DB01231
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Diphenidol.
DB01409
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Tiotropium.
DB01591
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Solifenacin.
DB01625
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Isopropamide.
DB04843
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Mepenzolate.
DB06153
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Pizotifen.
DB06702
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Fesoterodine.
DB06787
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Hexocyclium.
DB08801
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Dimetindene.
DB08897
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Aclidinium.
DB08997
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Dexetimide.
DB09076
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Umeclidinium.
DB09089
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Trimebutine.
DB09262
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Imidafenacin.
DB09300
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Butylscopolamine.
DB11235
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Thonzylamine.
DB11315
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Methscopolamine.
DB11855
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Revefenacin.
DB12086
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Oxitropium.
DB12278
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Propiverine.
DB12526
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Batefenterol.
DB13252
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Tropatepine.
DB13254
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Prifinium.
DB13351
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Piperidolate.
DB13369
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Benzilone.
DB13380
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Difemerine.
DB13413
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Phenglutarimide.
DB13448
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Mazaticol.
DB13468
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Etybenzatropine.
DB13500
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Otilonium.
DB13507
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Poldine.
DB13542
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Bevonium.
DB13581
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Rociverine.
DB13619
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Bornaprine.
DB13636
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Etanautine.
DB13666
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Tiemonium iodide.
DB13678
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Dihexyverine.
DB13695
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Penthienate.
DB13720
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Diphemanil.
DB13738
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Camylofin.
DB13759
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Fenpiverinium.
DB13769
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Emetonium iodide.
DB13844
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Pipenzolate.
DB13850
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Timepidium.
DB09007
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Chlorphenoxamine.
DB01198
The risk or severity of adverse effects can be increased when Baclofen is combined with Zopiclone.
DB00042
The risk or severity of adverse effects can be increased when Botulinum Toxin Type B is combined with Baclofen.
DB00083
The risk or severity of adverse effects can be increased when Botulinum toxin type A is combined with Baclofen.
DB00150
The risk or severity of adverse effects can be increased when Tryptophan is combined with Baclofen.
DB00186
The risk or severity of adverse effects can be increased when Baclofen is combined with Lorazepam.
DB00189
The risk or severity of adverse effects can be increased when Baclofen is combined with Ethchlorvynol.
DB00216
The risk or severity of adverse effects can be increased when Baclofen is combined with Eletriptan.
DB00228
The risk or severity of adverse effects can be increased when Baclofen is combined with Enflurane.
DB00231
The risk or severity of adverse effects can be increased when Baclofen is combined with Temazepam.
DB00234
The risk or severity of adverse effects can be increased when Baclofen is combined with Reboxetine.
DB00237
The risk or severity of adverse effects can be increased when Baclofen is combined with Butabarbital.
DB00241
The risk or severity of adverse effects can be increased when Baclofen is combined with Butalbital.
DB00247
The risk or severity of adverse effects can be increased when Baclofen is combined with Methysergide.
DB00248
The risk or severity of adverse effects can be increased when Baclofen is combined with Cabergoline.
DB00252
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenytoin.
DB00283
The risk or severity of adverse effects can be increased when Baclofen is combined with Clemastine.
DB00285
The risk or severity of adverse effects can be increased when Baclofen is combined with Venlafaxine.
DB00289
The risk or severity of adverse effects can be increased when Baclofen is combined with Atomoxetine.
DB00292
The risk or severity of adverse effects can be increased when Baclofen is combined with Etomidate.
DB00295
The risk or severity of adverse effects can be increased when Baclofen is combined with Morphine.
DB00306
The risk or severity of adverse effects can be increased when Baclofen is combined with Talbutal.
DB00312
The risk or severity of adverse effects can be increased when Baclofen is combined with Pentobarbital.
DB00313
The risk or severity of adverse effects can be increased when Baclofen is combined with Valproic acid.
DB00315
The risk or severity of adverse effects can be increased when Baclofen is combined with Zolmitriptan.
DB00320
The risk or severity of adverse effects can be increased when Baclofen is combined with Dihydroergotamine.
DB00323
The risk or severity of adverse effects can be increased when Baclofen is combined with Tolcapone.
DB00327
The risk or severity of adverse effects can be increased when Baclofen is combined with Hydromorphone.
DB00334
The risk or severity of adverse effects can be increased when Baclofen is combined with Olanzapine.
DB00341
The risk or severity of adverse effects can be increased when Baclofen is combined with Cetirizine.
DB00347
The risk or severity of adverse effects can be increased when Baclofen is combined with Trimethadione.
DB00349
The risk or severity of adverse effects can be increased when Baclofen is combined with Clobazam.
DB00356
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorzoxazone.
DB00363
The risk or severity of adverse effects can be increased when Baclofen is combined with Clozapine.
DB00371
The risk or severity of adverse effects can be increased when Baclofen is combined with Meprobamate.
DB00372
The risk or severity of adverse effects can be increased when Baclofen is combined with Thiethylperazine.
DB00391
The risk or severity of adverse effects can be increased when Baclofen is combined with Sulpiride.
DB00404
The risk or severity of adverse effects can be increased when Baclofen is combined with Alprazolam.
DB00405
The risk or severity of adverse effects can be increased when Baclofen is combined with Dexbrompheniramine.
DB00408
The risk or severity of adverse effects can be increased when Baclofen is combined with Loxapine.
DB00409
The risk or severity of adverse effects can be increased when Baclofen is combined with Remoxipride.
DB00418
The risk or severity of adverse effects can be increased when Baclofen is combined with Secobarbital.
DB00420
The risk or severity of adverse effects can be increased when Baclofen is combined with Promazine.
DB00423
The risk or severity of adverse effects can be increased when Baclofen is combined with Methocarbamol.
DB00427
The risk or severity of adverse effects can be increased when Baclofen is combined with Triprolidine.
DB00433
The risk or severity of adverse effects can be increased when Baclofen is combined with Prochlorperazine.
DB00463
The risk or severity of adverse effects can be increased when Baclofen is combined with Metharbital.
DB00474
The risk or severity of adverse effects can be increased when Baclofen is combined with Methohexital.
DB00475
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlordiazepoxide.
DB00477
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorpromazine.
DB00494
The risk or severity of adverse effects can be increased when Baclofen is combined with Entacapone.
DB00497
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxycodone.
DB00508
The risk or severity of adverse effects can be increased when Baclofen is combined with Triflupromazine.
DB00514
The risk or severity of adverse effects can be increased when Baclofen is combined with Dextromethorphan.
DB00532
The risk or severity of adverse effects can be increased when Baclofen is combined with Mephenytoin.
DB00546
The risk or severity of adverse effects can be increased when Baclofen is combined with Adinazolam.
DB00555
The risk or severity of adverse effects can be increased when Baclofen is combined with Lamotrigine.
DB00574
The risk or severity of adverse effects can be increased when Baclofen is combined with Fenfluramine.
DB00579
The risk or severity of adverse effects can be increased when Baclofen is combined with Mazindol.
DB00588
The risk or severity of adverse effects can be increased when Baclofen is combined with Fluticasone propionate.
DB00589
The risk or severity of adverse effects can be increased when Baclofen is combined with Lisuride.
DB00593
The risk or severity of adverse effects can be increased when Baclofen is combined with Ethosuximide.
DB00599
The risk or severity of adverse effects can be increased when Baclofen is combined with Thiopental.
DB00604
The risk or severity of adverse effects can be increased when Baclofen is combined with Cisapride.
DB00611
The risk or severity of adverse effects can be increased when Baclofen is combined with Butorphanol.
DB00617
The risk or severity of adverse effects can be increased when Baclofen is combined with Paramethadione.
DB00623
The risk or severity of adverse effects can be increased when Baclofen is combined with Fluphenazine.
DB00625
The risk or severity of adverse effects can be increased when Baclofen is combined with Efavirenz.
DB00628
The risk or severity of adverse effects can be increased when Baclofen is combined with Clorazepic acid.
DB00633
The risk or severity of adverse effects can be increased when Baclofen is combined with Dexmedetomidine.
DB00645
The risk or severity of adverse effects can be increased when Baclofen is combined with Dyclonine.
DB00647
The risk or severity of adverse effects can be increased when Baclofen is combined with Dextropropoxyphene.
DB00652
The risk or severity of adverse effects can be increased when Baclofen is combined with Pentazocine.
DB00660
The risk or severity of adverse effects can be increased when Baclofen is combined with Metaxalone.
DB00662
The risk or severity of adverse effects can be increased when Baclofen is combined with Trimethobenzamide.
DB00679
The risk or severity of adverse effects can be increased when Baclofen is combined with Thioridazine.
DB00680
The risk or severity of adverse effects can be increased when Baclofen is combined with Moricizine.
DB00683
The risk or severity of adverse effects can be increased when Baclofen is combined with Midazolam.
DB00690
The risk or severity of adverse effects can be increased when Baclofen is combined with Flurazepam.
DB00696
The risk or severity of adverse effects can be increased when Baclofen is combined with Ergotamine.
DB00697
The risk or severity of adverse effects can be increased when Baclofen is combined with Tizanidine.
DB00708
The risk or severity of adverse effects can be increased when Baclofen is combined with Sufentanil.
DB00714
The risk or severity of adverse effects can be increased when Baclofen is combined with Apomorphine.
DB00734
The risk or severity of adverse effects can be increased when Baclofen is combined with Risperidone.
DB00737
The risk or severity of adverse effects can be increased when Baclofen is combined with Meclizine.
DB00740
The risk or severity of adverse effects can be increased when Baclofen is combined with Riluzole.
DB00747
The risk or severity of adverse effects can be increased when Baclofen is combined with Scopolamine.
DB00748
The risk or severity of adverse effects can be increased when Baclofen is combined with Carbinoxamine.
DB00753
The risk or severity of adverse effects can be increased when Baclofen is combined with Isoflurane.
DB00754
The risk or severity of adverse effects can be increased when Baclofen is combined with Ethotoin.
DB00757
The risk or severity of adverse effects can be increased when Baclofen is combined with Dolasetron.
DB00771
The risk or severity of adverse effects can be increased when Baclofen is combined with Clidinium.
DB00776
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxcarbazepine.
DB00794
The risk or severity of adverse effects can be increased when Baclofen is combined with Primidone.
DB00801
The risk or severity of adverse effects can be increased when Baclofen is combined with Halazepam.
DB00802
The risk or severity of adverse effects can be increased when Baclofen is combined with Alfentanil.
DB00818
The risk or severity of adverse effects can be increased when Baclofen is combined with Propofol.
DB00819
The risk or severity of adverse effects can be increased when Baclofen is combined with Acetazolamide.
DB00829
The risk or severity of adverse effects can be increased when Baclofen is combined with Diazepam.
DB00831
The risk or severity of adverse effects can be increased when Baclofen is combined with Trifluoperazine.
DB00832
The risk or severity of adverse effects can be increased when Baclofen is combined with Phensuximide.
DB00835
The risk or severity of adverse effects can be increased when Baclofen is combined with Brompheniramine.
DB00837
The risk or severity of adverse effects can be increased when Baclofen is combined with Progabide.
DB00842
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxazepam.
DB00843
The risk or severity of adverse effects can be increased when Baclofen is combined with Donepezil.
DB00844
The risk or severity of adverse effects can be increased when Baclofen is combined with Nalbuphine.
DB00849
The risk or severity of adverse effects can be increased when Baclofen is combined with Methylphenobarbital.
DB00850
The risk or severity of adverse effects can be increased when Baclofen is combined with Perphenazine.
DB00854
The risk or severity of adverse effects can be increased when Baclofen is combined with Levorphanol.
DB00865
The risk or severity of adverse effects can be increased when Baclofen is combined with Benzphetamine.
DB00875
The risk or severity of adverse effects can be increased when Baclofen is combined with Flupentixol.
DB00889
The risk or severity of adverse effects can be increased when Baclofen is combined with Granisetron.
DB00897
The risk or severity of adverse effects can be increased when Baclofen is combined with Triazolam.
DB00899
The risk or severity of adverse effects can be increased when Baclofen is combined with Remifentanil.
DB00904
The risk or severity of adverse effects can be increased when Baclofen is combined with Ondansetron.
DB00906
The risk or severity of adverse effects can be increased when Baclofen is combined with Tiagabine.
DB00909
The risk or severity of adverse effects can be increased when Baclofen is combined with Zonisamide.
DB00933
The risk or severity of adverse effects can be increased when Baclofen is combined with Mesoridazine.
DB00937
The risk or severity of adverse effects can be increased when Baclofen is combined with Diethylpropion.
DB00941
The risk or severity of adverse effects can be increased when Baclofen is combined with Hexafluronium.
DB00949
The risk or severity of adverse effects can be increased when Baclofen is combined with Felbamate.
DB00952
The risk or severity of adverse effects can be increased when Baclofen is combined with Naratriptan.
DB00962
The risk or severity of adverse effects can be increased when Baclofen is combined with Zaleplon.
DB00967
The risk or severity of adverse effects can be increased when Baclofen is combined with Desloratadine.
DB00969
The risk or severity of adverse effects can be increased when Baclofen is combined with Alosetron.
DB00980
The risk or severity of adverse effects can be increased when Baclofen is combined with Ramelteon.
DB00985
The risk or severity of adverse effects can be increased when Baclofen is combined with Dimenhydrinate.
DB00996
The risk or severity of adverse effects can be increased when Baclofen is combined with Gabapentin.
DB00998
The risk or severity of adverse effects can be increased when Baclofen is combined with Frovatriptan.
DB01028
The risk or severity of adverse effects can be increased when Baclofen is combined with Methoxyflurane.
DB01049
The risk or severity of adverse effects can be increased when Baclofen is combined with Ergoloid mesylate.
DB01063
The risk or severity of adverse effects can be increased when Baclofen is combined with Acetophenazine.
DB01065
The risk or severity of adverse effects can be increased when Baclofen is combined with Melatonin.
DB01068
The risk or severity of adverse effects can be increased when Baclofen is combined with Clonazepam.
DB01069
The risk or severity of adverse effects can be increased when Baclofen is combined with Promethazine.
DB01075
The risk or severity of adverse effects can be increased when Baclofen is combined with Diphenhydramine.
DB01080
The risk or severity of adverse effects can be increased when Baclofen is combined with Vigabatrin.
DB01081
The risk or severity of adverse effects can be increased when Baclofen is combined with Diphenoxylate.
DB01100
The risk or severity of adverse effects can be increased when Baclofen is combined with Pimozide.
DB01107
The risk or severity of adverse effects can be increased when Baclofen is combined with Methyprylon.
DB01114
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorpheniramine.
DB01121
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenacemide.
DB01154
The risk or severity of adverse effects can be increased when Baclofen is combined with Thiamylal.
DB01156
The risk or severity of adverse effects can be increased when Baclofen is combined with Bupropion.
DB01159
The risk or severity of adverse effects can be increased when Baclofen is combined with Halothane.
DB01174
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenobarbital.
DB01176
The risk or severity of adverse effects can be increased when Baclofen is combined with Cyclizine.
DB01178
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlormezanone.
DB01186
The risk or severity of adverse effects can be increased when Baclofen is combined with Pergolide.
DB01189
The risk or severity of adverse effects can be increased when Baclofen is combined with Desflurane.
DB01192
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxymorphone.
DB01202
The risk or severity of adverse effects can be increased when Baclofen is combined with Levetiracetam.
DB01209
The risk or severity of adverse effects can be increased when Baclofen is combined with Dezocine.
DB01215
The risk or severity of adverse effects can be increased when Baclofen is combined with Estazolam.
DB01219
The risk or severity of adverse effects can be increased when Baclofen is combined with Dantrolene.
DB01221
The risk or severity of adverse effects can be increased when Baclofen is combined with Ketamine.
DB01224
The risk or severity of adverse effects can be increased when Baclofen is combined with Quetiapine.
DB01227
The risk or severity of adverse effects can be increased when Baclofen is combined with Levacetylmethadol.
DB01236
The risk or severity of adverse effects can be increased when Baclofen is combined with Sevoflurane.
DB01238
The risk or severity of adverse effects can be increased when Baclofen is combined with Aripiprazole.
DB01239
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorprothixene.
DB01246
The risk or severity of adverse effects can be increased when Baclofen is combined with Alimemazine.
DB01253
The risk or severity of adverse effects can be increased when Baclofen is combined with Ergometrine.
DB01267
The risk or severity of adverse effects can be increased when Baclofen is combined with Paliperidone.
DB01320
The risk or severity of adverse effects can be increased when Baclofen is combined with Fosphenytoin.
DB01323
The risk or severity of adverse effects can be increased when Baclofen is combined with St. John's Wort.
DB01351
The risk or severity of adverse effects can be increased when Baclofen is combined with Amobarbital.
DB01352
The risk or severity of adverse effects can be increased when Baclofen is combined with Aprobarbital.
DB01353
The risk or severity of adverse effects can be increased when Baclofen is combined with Butobarbital.
DB01354
The risk or severity of adverse effects can be increased when Baclofen is combined with Heptabarbital.
DB01355
The risk or severity of adverse effects can be increased when Baclofen is combined with Hexobarbital.
DB01392
The risk or severity of adverse effects can be increased when Baclofen is combined with Yohimbine.
DB01433
The risk or severity of adverse effects can be increased when Baclofen is combined with Methadyl acetate.
DB01437
The risk or severity of adverse effects can be increased when Baclofen is combined with Glutethimide.
DB01440
The risk or severity of adverse effects can be increased when Baclofen is combined with gamma-Hydroxybutyric acid.
DB01442
The risk or severity of adverse effects can be increased when Baclofen is combined with MMDA.
DB01445
The risk or severity of adverse effects can be increased when Baclofen is combined with Bufotenine.
DB01450
The risk or severity of adverse effects can be increased when Baclofen is combined with Dihydroetorphine.
DB01452
The risk or severity of adverse effects can be increased when Baclofen is combined with Diamorphine.
DB01454
The risk or severity of adverse effects can be increased when Baclofen is combined with Midomafetamine.
DB01463
The risk or severity of adverse effects can be increased when Baclofen is combined with Fencamfamin.
DB01466
The risk or severity of adverse effects can be increased when Baclofen is combined with Ethylmorphine.
DB01472
The risk or severity of adverse effects can be increased when Baclofen is combined with 4-Methoxyamphetamine.
DB01483
The risk or severity of adverse effects can be increased when Baclofen is combined with Barbital.
DB01484
The risk or severity of adverse effects can be increased when Baclofen is combined with 4-Bromo-2,5-dimethoxyamphetamine.
DB01488
The risk or severity of adverse effects can be increased when Baclofen is combined with Dimethyltryptamine.
DB01489
The risk or severity of adverse effects can be increased when Baclofen is combined with Camazepam.
DB01495
The risk or severity of adverse effects can be increased when Baclofen is combined with Dichloralphenazone.
DB01497
The risk or severity of adverse effects can be increased when Baclofen is combined with Etorphine.
DB01501
The risk or severity of adverse effects can be increased when Baclofen is combined with Difenoxin.
DB01509
The risk or severity of adverse effects can be increased when Baclofen is combined with Tenamfetamine.
DB01511
The risk or severity of adverse effects can be increased when Baclofen is combined with Delorazepam.
DB01529
The risk or severity of adverse effects can be increased when Baclofen is combined with Dextromoramide.
DB01531
The risk or severity of adverse effects can be increased when Baclofen is combined with Desomorphine.
DB01534
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorhexadol.
DB01535
The risk or severity of adverse effects can be increased when Baclofen is combined with Carfentanil.
DB01544
The risk or severity of adverse effects can be increased when Baclofen is combined with Flunitrazepam.
DB01545
The risk or severity of adverse effects can be increased when Baclofen is combined with Ethyl loflazepate.
DB01547
The risk or severity of adverse effects can be increased when Baclofen is combined with Drotebanol.
DB01551
The risk or severity of adverse effects can be increased when Baclofen is combined with Dihydrocodeine.
DB01553
The risk or severity of adverse effects can be increased when Baclofen is combined with Cloxazolam.
DB01555
The risk or severity of adverse effects can be increased when Baclofen is combined with Alphacetylmethadol.
DB01558
The risk or severity of adverse effects can be increased when Baclofen is combined with Bromazepam.
DB01559
The risk or severity of adverse effects can be increased when Baclofen is combined with Clotiazepam.
DB01560
The risk or severity of adverse effects can be increased when Baclofen is combined with Cathinone.
DB01563
The risk or severity of adverse effects can be increased when Baclofen is combined with Chloral hydrate.
DB01565
The risk or severity of adverse effects can be increased when Baclofen is combined with Dihydromorphine.
DB01567
The risk or severity of adverse effects can be increased when Baclofen is combined with Fludiazepam.
DB01587
The risk or severity of adverse effects can be increased when Baclofen is combined with Ketazolam.
DB01588
The risk or severity of adverse effects can be increased when Baclofen is combined with Prazepam.
DB01589
The risk or severity of adverse effects can be increased when Baclofen is combined with Quazepam.
DB01594
The risk or severity of adverse effects can be increased when Baclofen is combined with Cinolazepam.
DB01595
The risk or severity of adverse effects can be increased when Baclofen is combined with Nitrazepam.
DB01608
The risk or severity of adverse effects can be increased when Baclofen is combined with Periciazine.
DB01614
The risk or severity of adverse effects can be increased when Baclofen is combined with Acepromazine.
DB01615
The risk or severity of adverse effects can be increased when Baclofen is combined with Aceprometazine.
DB01616
The risk or severity of adverse effects can be increased when Baclofen is combined with Alverine.
DB01618
The risk or severity of adverse effects can be increased when Baclofen is combined with Molindone.
DB01621
The risk or severity of adverse effects can be increased when Baclofen is combined with Pipotiazine.
DB01622
The risk or severity of adverse effects can be increased when Baclofen is combined with Thioproperazine.
DB01623
The risk or severity of adverse effects can be increased when Baclofen is combined with Thiothixene.
DB01624
The risk or severity of adverse effects can be increased when Baclofen is combined with Zuclopenthixol.
DB01954
The risk or severity of adverse effects can be increased when Baclofen is combined with Rolipram.
DB02207
The risk or severity of adverse effects can be increased when Baclofen is combined with 7-Nitroindazole.
DB02234
The risk or severity of adverse effects can be increased when Baclofen is combined with S-Ethylisothiourea.
DB02852
The risk or severity of adverse effects can be increased when Baclofen is combined with Domoic Acid.
DB02959
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxitriptan.
DB03575
The risk or severity of adverse effects can be increased when Baclofen is combined with Phencyclidine.
DB04165
The risk or severity of adverse effects can be increased when Baclofen is combined with Valpromide.
DB04325
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenethylamine.
DB04599
The risk or severity of adverse effects can be increased when Baclofen is combined with Aniracetam.
DB04819
The risk or severity of adverse effects can be increased when Baclofen is combined with Methapyrilene.
DB04821
The risk or severity of adverse effects can be increased when Baclofen is combined with Nomifensine.
DB04827
The risk or severity of adverse effects can be increased when Baclofen is combined with Urethane.
DB04829
The risk or severity of adverse effects can be increased when Baclofen is combined with Lysergic acid diethylamide.
DB04833
The risk or severity of adverse effects can be increased when Baclofen is combined with Methaqualone.
DB04841
The risk or severity of adverse effects can be increased when Baclofen is combined with Flunarizine.
DB04842
The risk or severity of adverse effects can be increased when Baclofen is combined with Fluspirilene.
DB04872
The risk or severity of adverse effects can be increased when Baclofen is combined with Osanetant.
DB04885
The risk or severity of adverse effects can be increased when Baclofen is combined with Cilansetron.
DB04888
The risk or severity of adverse effects can be increased when Baclofen is combined with Bifeprunox.
DB04903
The risk or severity of adverse effects can be increased when Baclofen is combined with Pagoclone.
DB04908
The risk or severity of adverse effects can be increased when Baclofen is combined with Flibanserin.
DB04917
The risk or severity of adverse effects can be increased when Baclofen is combined with Renzapride.
DB04946
The risk or severity of adverse effects can be increased when Baclofen is combined with Iloperidone.
DB04953
The risk or severity of adverse effects can be increased when Baclofen is combined with Ezogabine.
DB05227
The risk or severity of adverse effects can be increased when Baclofen is combined with APD791.
DB05232
The risk or severity of adverse effects can be increased when Baclofen is combined with Tetrodotoxin.
DB05246
The risk or severity of adverse effects can be increased when Baclofen is combined with Methsuximide.
DB05316
The risk or severity of adverse effects can be increased when Baclofen is combined with Pimavanserin.
DB05541
The risk or severity of adverse effects can be increased when Baclofen is combined with Brivaracetam.
DB05542
The risk or severity of adverse effects can be increased when Baclofen is combined with Naronapride.
DB05562
The risk or severity of adverse effects can be increased when Baclofen is combined with Naluzotan.
DB05607
The risk or severity of adverse effects can be increased when Baclofen is combined with PRX-08066.
DB05687
The risk or severity of adverse effects can be increased when Baclofen is combined with BL-1020.
DB05710
The risk or severity of adverse effects can be increased when Baclofen is combined with Gantacurium.
DB06016
The risk or severity of adverse effects can be increased when Baclofen is combined with Cariprazine.
DB06077
The risk or severity of adverse effects can be increased when Baclofen is combined with Lumateperone.
DB06109
The risk or severity of adverse effects can be increased when Baclofen is combined with YKP-1358.
DB06144
The risk or severity of adverse effects can be increased when Baclofen is combined with Sertindole.
DB06148
The risk or severity of adverse effects can be increased when Baclofen is combined with Mianserin.
DB06216
The risk or severity of adverse effects can be increased when Baclofen is combined with Asenapine.
DB06218
The risk or severity of adverse effects can be increased when Baclofen is combined with Lacosamide.
DB06264
The risk or severity of adverse effects can be increased when Baclofen is combined with Tolperisone.
DB06282
The risk or severity of adverse effects can be increased when Baclofen is combined with Levocetirizine.
DB06283
The risk or severity of adverse effects can be increased when Baclofen is combined with Ziconotide.
DB06288
The risk or severity of adverse effects can be increased when Baclofen is combined with Amisulpride.
DB06446
The risk or severity of adverse effects can be increased when Baclofen is combined with Dotarizine.
DB06458
The risk or severity of adverse effects can be increased when Baclofen is combined with Remacemide.
DB06470
The risk or severity of adverse effects can be increased when Baclofen is combined with Clomethiazole.
DB06512
The risk or severity of adverse effects can be increased when Baclofen is combined with Deramciclane.
DB06527
The risk or severity of adverse effects can be increased when Baclofen is combined with Tramiprosate.
DB06529
The risk or severity of adverse effects can be increased when Baclofen is combined with Ocinaplon.
DB06554
The risk or severity of adverse effects can be increased when Baclofen is combined with Gaboxadol.
DB06579
The risk or severity of adverse effects can be increased when Baclofen is combined with Adipiplon.
DB06582
The risk or severity of adverse effects can be increased when Baclofen is combined with Dextofisopam.
DB06594
The risk or severity of adverse effects can be increased when Baclofen is combined with Agomelatine.
DB06660
The risk or severity of adverse effects can be increased when Baclofen is combined with Saredutant.
DB06678
The risk or severity of adverse effects can be increased when Baclofen is combined with Esmirtazapine.
DB06684
The risk or severity of adverse effects can be increased when Baclofen is combined with Vilazodone.
DB06690
The risk or severity of adverse effects can be increased when Baclofen is combined with Nitrous oxide.
DB06691
The risk or severity of adverse effects can be increased when Baclofen is combined with Mepyramine.
DB06701
The risk or severity of adverse effects can be increased when Baclofen is combined with Dexmethylphenidate.
DB06716
The risk or severity of adverse effects can be increased when Baclofen is combined with Fospropofol.
DB06738
The risk or severity of adverse effects can be increased when Baclofen is combined with Ketobemidone.
DB06753
The risk or severity of adverse effects can be increased when Baclofen is combined with Triclofos.
DB06770
The risk or severity of adverse effects can be increased when Baclofen is combined with Benzyl alcohol.
DB06797
The risk or severity of adverse effects can be increased when Baclofen is combined with Mebutamate.
DB08059
The risk or severity of adverse effects can be increased when Baclofen is combined with Wortmannin.
DB08329
The risk or severity of adverse effects can be increased when Baclofen is combined with Sulthiame.
DB08810
The risk or severity of adverse effects can be increased when Baclofen is combined with Cinitapride.
DB08811
The risk or severity of adverse effects can be increased when Baclofen is combined with Tofisopam.
DB08815
The risk or severity of adverse effects can be increased when Baclofen is combined with Lurasidone.
DB08839
The risk or severity of adverse effects can be increased when Baclofen is combined with Serotonin.
DB08861
The risk or severity of adverse effects can be increased when Baclofen is combined with DPDPE.
DB08872
The risk or severity of adverse effects can be increased when Baclofen is combined with Gabapentin enacarbil.
DB08892
The risk or severity of adverse effects can be increased when Baclofen is combined with Arbaclofen Placarbil.
DB08910
The risk or severity of adverse effects can be increased when Baclofen is combined with Pomalidomide.
DB08922
The risk or severity of adverse effects can be increased when Baclofen is combined with Perospirone.
DB08927
The risk or severity of adverse effects can be increased when Baclofen is combined with Amperozide.
DB08954
The risk or severity of adverse effects can be increased when Baclofen is combined with Ifenprodil.
DB08986
The risk or severity of adverse effects can be increased when Baclofen is combined with Etifoxine.
DB08992
The risk or severity of adverse effects can be increased when Baclofen is combined with Eperisone.
DB09000
The risk or severity of adverse effects can be increased when Baclofen is combined with Cyamemazine.
DB09001
The risk or severity of adverse effects can be increased when Baclofen is combined with Barbexaclone.
DB09011
The risk or severity of adverse effects can be increased when Baclofen is combined with Beclamide.
DB09014
The risk or severity of adverse effects can be increased when Baclofen is combined with Captodiame.
DB09017
The risk or severity of adverse effects can be increased when Baclofen is combined with Brotizolam.
DB09021
The risk or severity of adverse effects can be increased when Baclofen is combined with Benzoctamine.
DB09023
The risk or severity of adverse effects can be increased when Baclofen is combined with Benactyzine.
DB09071
The risk or severity of adverse effects can be increased when Baclofen is combined with Tasimelteon.
DB09118
The risk or severity of adverse effects can be increased when Baclofen is combined with Stiripentol.
DB09119
The risk or severity of adverse effects can be increased when Baclofen is combined with Eslicarbazepine acetate.
DB09128
The risk or severity of adverse effects can be increased when Baclofen is combined with Brexpiprazole.
DB09166
The risk or severity of adverse effects can be increased when Baclofen is combined with Etizolam.
DB09174
The risk or severity of adverse effects can be increased when Baclofen is combined with Lofentanil.
DB09184
The risk or severity of adverse effects can be increased when Baclofen is combined with Edivoxetine.
DB09186
The risk or severity of adverse effects can be increased when Baclofen is combined with Nisoxetine.
DB09187
The risk or severity of adverse effects can be increased when Baclofen is combined with Lortalamine.
DB09190
The risk or severity of adverse effects can be increased when Baclofen is combined with Talopram.
DB09223
The risk or severity of adverse effects can be increased when Baclofen is combined with Blonanserin.
DB09224
The risk or severity of adverse effects can be increased when Baclofen is combined with Melperone.
DB09225
The risk or severity of adverse effects can be increased when Baclofen is combined with Zotepine.
DB09226
The risk or severity of adverse effects can be increased when Baclofen is combined with Brilaroxazine.
DB09247
The risk or severity of adverse effects can be increased when Baclofen is combined with Iproclozide.
DB09286
The risk or severity of adverse effects can be increased when Baclofen is combined with Pipamperone.
DB09290
The risk or severity of adverse effects can be increased when Baclofen is combined with Ramosetron.
DB11130
The risk or severity of adverse effects can be increased when Baclofen is combined with Opium.
DB11371
The risk or severity of adverse effects can be increased when Baclofen is combined with Alfaxalone.
DB11376
The risk or severity of adverse effects can be increased when Baclofen is combined with Azaperone.
DB11400
The risk or severity of adverse effects can be increased when Baclofen is combined with Doramectin.
DB11428
The risk or severity of adverse effects can be increased when Baclofen is combined with Medetomidine.
DB11477
The risk or severity of adverse effects can be increased when Baclofen is combined with Xylazine.
DB11540
The risk or severity of adverse effects can be increased when Baclofen is combined with Propiopromazine.
DB11543
The risk or severity of adverse effects can be increased when Baclofen is combined with Romifidine.
DB11549
The risk or severity of adverse effects can be increased when Baclofen is combined with Tiletamine.
DB11552
The risk or severity of adverse effects can be increased when Baclofen is combined with Tricaine.
DB11555
The risk or severity of adverse effects can be increased when Baclofen is combined with Zolazepam.
DB11556
The risk or severity of adverse effects can be increased when Baclofen is combined with Detomidine.
DB11582
The risk or severity of adverse effects can be increased when Baclofen is combined with Thiocolchicoside.
DB11609
The risk or severity of adverse effects can be increased when Baclofen is combined with Normethadone.
DB11664
The risk or severity of adverse effects can be increased when Baclofen is combined with Psilocybin.
DB11675
The risk or severity of adverse effects can be increased when Baclofen is combined with Mosapride.
DB11686
The risk or severity of adverse effects can be increased when Baclofen is combined with Iferanserin.
DB11755
The risk or severity of adverse effects can be increased when Baclofen is combined with Tetrahydrocannabivarin.
DB11859
The risk or severity of adverse effects can be increased when Baclofen is combined with Brexanolone.
DB11868
The risk or severity of adverse effects can be increased when Baclofen is combined with Etiracetam.
DB11889
The risk or severity of adverse effects can be increased when Baclofen is combined with Lanicemine.
DB11957
The risk or severity of adverse effects can be increased when Baclofen is combined with Idalopirdine.
DB12071
The risk or severity of adverse effects can be increased when Baclofen is combined with Vabicaserin.
DB12105
The risk or severity of adverse effects can be increased when Baclofen is combined with Imagabalin.
DB12110
The risk or severity of adverse effects can be increased when Baclofen is combined with m-Chlorophenylpiperazine.
DB12111
The risk or severity of adverse effects can be increased when Baclofen is combined with MK-212.
DB12131
The risk or severity of adverse effects can be increased when Baclofen is combined with Vinpocetine.
DB12163
The risk or severity of adverse effects can be increased when Baclofen is combined with Sarpogrelate.
DB12177
The risk or severity of adverse effects can be increased when Baclofen is combined with Eplivanserin.
DB12184
The risk or severity of adverse effects can be increased when Baclofen is combined with Gepirone.
DB12229
The risk or severity of adverse effects can be increased when Baclofen is combined with Cerlapirdine.
DB12273
The risk or severity of adverse effects can be increased when Baclofen is combined with Ecopipam.
DB12308
The risk or severity of adverse effects can be increased when Baclofen is combined with Eltanolone.
DB12327
The risk or severity of adverse effects can be increased when Baclofen is combined with Salvinorin A.
DB12338
The risk or severity of adverse effects can be increased when Baclofen is combined with Carisbamate.
DB12361
The risk or severity of adverse effects can be increased when Baclofen is combined with Piclozotan.
DB12395
The risk or severity of adverse effects can be increased when Baclofen is combined with Esreboxetine.
DB12401
The risk or severity of adverse effects can be increased when Baclofen is combined with Bromperidol.
DB12427
The risk or severity of adverse effects can be increased when Baclofen is combined with Orvepitant.
DB12492
The risk or severity of adverse effects can be increased when Baclofen is combined with Piritramide.
DB12518
The risk or severity of adverse effects can be increased when Baclofen is combined with Raclopride.
DB12537
The risk or severity of adverse effects can be increased when Baclofen is combined with Benzodiazepine.
DB12576
The risk or severity of adverse effects can be increased when Baclofen is combined with AZD-3043.
DB12590
The risk or severity of adverse effects can be increased when Baclofen is combined with Indiplon.
DB12710
The risk or severity of adverse effects can be increased when Baclofen is combined with Perazine.
DB12725
The risk or severity of adverse effects can be increased when Baclofen is combined with TD-8954.
DB12833
The risk or severity of adverse effects can be increased when Baclofen is combined with Tandospirone.
DB12867
The risk or severity of adverse effects can be increased when Baclofen is combined with Benperidol.
DB12883
The risk or severity of adverse effects can be increased when Baclofen is combined with Eltoprazine.
DB12951
The risk or severity of adverse effects can be increased when Baclofen is combined with Pivagabine.
DB12958
The risk or severity of adverse effects can be increased when Baclofen is combined with Prothipendyl.
DB13014
The risk or severity of adverse effects can be increased when Baclofen is combined with Hypericin.
DB13025
The risk or severity of adverse effects can be increased when Baclofen is combined with Tiapride.
DB13082
The risk or severity of adverse effects can be increased when Baclofen is combined with Nefiracetam.
DB13099
The risk or severity of adverse effects can be increased when Baclofen is combined with Valnoctamide.
DB13160
The risk or severity of adverse effects can be increased when Baclofen is combined with Alphaprodine.
DB13213
The risk or severity of adverse effects can be increased when Baclofen is combined with Butaperazine.
DB13219
The risk or severity of adverse effects can be increased when Baclofen is combined with Medifoxamine.
DB13221
The risk or severity of adverse effects can be increased when Baclofen is combined with Apronalide.
DB13234
The risk or severity of adverse effects can be increased when Baclofen is combined with Propanidid.
DB13253
The risk or severity of adverse effects can be increased when Baclofen is combined with Proxibarbal.
DB13256
The risk or severity of adverse effects can be increased when Baclofen is combined with Clothiapine.
DB13273
The risk or severity of adverse effects can be increased when Baclofen is combined with Sultopride.
DB13303
The risk or severity of adverse effects can be increased when Baclofen is combined with Febarbamate.
DB13323
The risk or severity of adverse effects can be increased when Baclofen is combined with Trichloroethylene.
DB13324
The risk or severity of adverse effects can be increased when Baclofen is combined with Tetrazepam.
DB13331
The risk or severity of adverse effects can be increased when Baclofen is combined with Pyrithyldione.
DB13335
The risk or severity of adverse effects can be increased when Baclofen is combined with Pinazepam.
DB13352
The risk or severity of adverse effects can be increased when Baclofen is combined with Deanol.
DB13354
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenprobamate.
DB13357
The risk or severity of adverse effects can be increased when Baclofen is combined with Styramate.
DB13362
The risk or severity of adverse effects can be increased when Baclofen is combined with Pheneturide.
DB13370
The risk or severity of adverse effects can be increased when Baclofen is combined with Bromisoval.
DB13377
The risk or severity of adverse effects can be increased when Baclofen is combined with Vinbarbital.
DB13382
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorproethazine.
DB13396
The risk or severity of adverse effects can be increased when Baclofen is combined with Neocitrullamon.
DB13402
The risk or severity of adverse effects can be increased when Baclofen is combined with Acetylglycinamide chloral hydrate.
DB13403
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxypertine.
DB13414
The risk or severity of adverse effects can be increased when Baclofen is combined with Fenyramidol.
DB13420
The risk or severity of adverse effects can be increased when Baclofen is combined with Thiazinam.
DB13437
The risk or severity of adverse effects can be increased when Baclofen is combined with Medazepam.
DB13455
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenibut.
DB13457
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxaflozane.
DB13478
The risk or severity of adverse effects can be increased when Baclofen is combined with Meptazinol.
DB13505
The risk or severity of adverse effects can be increased when Baclofen is combined with Emepronium.
DB13520
The risk or severity of adverse effects can be increased when Baclofen is combined with Metergoline.
DB13522
The risk or severity of adverse effects can be increased when Baclofen is combined with Mebicar.
DB13523
The risk or severity of adverse effects can be increased when Baclofen is combined with Veralipride.
DB13534
The risk or severity of adverse effects can be increased when Baclofen is combined with Gedocarnil.
DB13541
The risk or severity of adverse effects can be increased when Baclofen is combined with Iprazochrome.
DB13550
The risk or severity of adverse effects can be increased when Baclofen is combined with Bifemelane.
DB13552
The risk or severity of adverse effects can be increased when Baclofen is combined with Trifluperidol.
DB13554
The risk or severity of adverse effects can be increased when Baclofen is combined with Moperone.
DB13557
The risk or severity of adverse effects can be increased when Baclofen is combined with Thiopropazate.
DB13572
The risk or severity of adverse effects can be increased when Baclofen is combined with Emylcamate.
DB13577
The risk or severity of adverse effects can be increased when Baclofen is combined with Allobarbital.
DB13588
The risk or severity of adverse effects can be increased when Baclofen is combined with Naftidrofuryl.
DB13598
The risk or severity of adverse effects can be increased when Baclofen is combined with Diethyl ether.
DB13601
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxiracetam.
DB13605
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenoperidine.
DB13606
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenazocine.
DB13623
The risk or severity of adverse effects can be increased when Baclofen is combined with Fabomotizole.
DB13642
The risk or severity of adverse effects can be increased when Baclofen is combined with Pridinol.
DB13643
The risk or severity of adverse effects can be increased when Baclofen is combined with Loprazolam.
DB13662
The risk or severity of adverse effects can be increased when Baclofen is combined with Hexapropymate.
DB13665
The risk or severity of adverse effects can be increased when Baclofen is combined with Fluanisone.
DB13676
The risk or severity of adverse effects can be increased when Baclofen is combined with Mosapramine.
DB13687
The risk or severity of adverse effects can be increased when Baclofen is combined with Niaprazine.
DB13690
The risk or severity of adverse effects can be increased when Baclofen is combined with Vinyl ether.
DB13733
The risk or severity of adverse effects can be increased when Baclofen is combined with Methylpentynol.
DB13737
The risk or severity of adverse effects can be increased when Baclofen is combined with Cyclobarbital.
DB13745
The risk or severity of adverse effects can be increased when Baclofen is combined with Fazadinium bromide.
DB13754
The risk or severity of adverse effects can be increased when Baclofen is combined with Mephenoxalone.
DB13770
The risk or severity of adverse effects can be increased when Baclofen is combined with Vinylbital.
DB13784
The risk or severity of adverse effects can be increased when Baclofen is combined with Dixyrazine.
DB13787
The risk or severity of adverse effects can be increased when Baclofen is combined with Tilidine.
DB13791
The risk or severity of adverse effects can be increased when Baclofen is combined with Penfluridol.
DB13799
The risk or severity of adverse effects can be increased when Baclofen is combined with Ethadione.
DB13805
The risk or severity of adverse effects can be increased when Baclofen is combined with Reposal.
DB13817
The risk or severity of adverse effects can be increased when Baclofen is combined with Carbromal.
DB13837
The risk or severity of adverse effects can be increased when Baclofen is combined with Doxefazepam.
DB13841
The risk or severity of adverse effects can be increased when Baclofen is combined with Clopenthixol.
DB13872
The risk or severity of adverse effects can be increased when Baclofen is combined with Lormetazepam.
DB13940
The risk or severity of adverse effects can be increased when Baclofen is combined with 2,5-Dimethoxy-4-ethylthioamphetamine.
DB13948
The risk or severity of adverse effects can be increased when Baclofen is combined with N-(2-hydroxybenzyl)-2,5-dimethoxy-4-cyanophenylethylamine.
DB13984
The risk or severity of adverse effects can be increased when Baclofen is combined with Cyclopropane.
DB13993
The risk or severity of adverse effects can be increased when Baclofen is combined with MRK-409.
DB14010
The risk or severity of adverse effects can be increased when Baclofen is combined with 5-methoxy-N,N-dimethyltryptamine.
DB14028
The risk or severity of adverse effects can be increased when Baclofen is combined with Nordazepam.
DB14050
The risk or severity of adverse effects can be increased when Baclofen is combined with Cannabidivarin.
DB14185
The risk or severity of adverse effects can be increased when Baclofen is combined with Aripiprazole lauroxil.
DB14575
The risk or severity of adverse effects can be increased when Baclofen is combined with Eslicarbazepine.
DB14651
The risk or severity of adverse effects can be increased when Baclofen is combined with Perphenazine enanthate.
DB14672
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxazepam acetate.
DB14715
The risk or severity of adverse effects can be increased when Baclofen is combined with Cinazepam.
DB14718
The risk or severity of adverse effects can be increased when Baclofen is combined with Pyrazolam.
DB14719
The risk or severity of adverse effects can be increased when Baclofen is combined with Bentazepam.
DB14754
The risk or severity of adverse effects can be increased when Baclofen is combined with Solriamfetol.
DB15203
The risk or severity of adverse effects can be increased when Baclofen is combined with JNJ-26489112.
DB15360
The risk or severity of adverse effects can be increased when Baclofen is combined with Carfentanil, C-11.
DB00377
The risk or severity of adverse effects can be increased when Baclofen is combined with Palonosetron.
DB00669
The risk or severity of adverse effects can be increased when Baclofen is combined with Sumatriptan.
DB00918
The risk or severity of adverse effects can be increased when Baclofen is combined with Almotriptan.
DB00953
The risk or severity of adverse effects can be increased when Baclofen is combined with Rizatriptan.
DB01577
The risk or severity of adverse effects can be increased when Baclofen is combined with Metamfetamine.
DB04871
The risk or severity of adverse effects can be increased when Baclofen is combined with Lorcaserin.
DB09068
The risk or severity of adverse effects can be increased when Baclofen is combined with Vortioxetine.
DB09185
The risk or severity of adverse effects can be increased when Baclofen is combined with Viloxazine.
DB09194
The risk or severity of adverse effects can be increased when Baclofen is combined with Etoperidone.
DB11699
The risk or severity of adverse effects can be increased when Baclofen is combined with Tropisetron.
DB00273
The risk or severity of adverse effects can be increased when Baclofen is combined with Topiramate.
DB11951
The risk or severity of adverse effects can be increased when Baclofen is combined with Lemborexant.
DB00318
The risk or severity of adverse effects can be increased when Baclofen is combined with Codeine.
DB00454
The risk or severity of adverse effects can be increased when Baclofen is combined with Meperidine.
DB00813
The risk or severity of adverse effects can be increased when Baclofen is combined with Fentanyl.
DB12404
The risk or severity of adverse effects can be increased when Baclofen is combined with Remimazolam.
DB00751
The risk or severity of adverse effects can be increased when Baclofen is combined with Epinastine.
DB00230
The therapeutic efficacy of Baclofen can be increased when used in combination with Pregabalin.
DB04948
The therapeutic efficacy of Baclofen can be increased when used in combination with Lofexidine.
DB09195
Lorpiprazole may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00014
Goserelin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00017
Salmon calcitonin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00035
Desmopressin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00041
Aldesleukin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00081
Tositumomab may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00115
Cyanocobalamin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00158
Folic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00165
Pyridoxine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00185
Baclofen may decrease the excretion rate of Cevimeline which could result in a higher serum level.
DB00190
Baclofen may decrease the excretion rate of Carbidopa which could result in a higher serum level.
DB00196
Baclofen may decrease the excretion rate of Fluconazole which could result in a higher serum level.
DB00198
Baclofen may decrease the excretion rate of Oseltamivir which could result in a higher serum level.
DB00200
Baclofen may decrease the excretion rate of Hydroxocobalamin which could result in a higher serum level.
DB00208
Baclofen may decrease the excretion rate of Ticlopidine which could result in a higher serum level.
DB00213
Baclofen may decrease the excretion rate of Pantoprazole which could result in a higher serum level.
DB00225
Baclofen may decrease the excretion rate of Gadodiamide which could result in a higher serum level.
DB00235
Baclofen may decrease the excretion rate of Milrinone which could result in a higher serum level.
DB00243
Baclofen may decrease the excretion rate of Ranolazine which could result in a higher serum level.
DB00254
Baclofen may decrease the excretion rate of Doxycycline which could result in a higher serum level.
DB00262
Baclofen may decrease the excretion rate of Carmustine which could result in a higher serum level.
DB00271
Baclofen may decrease the excretion rate of Diatrizoate which could result in a higher serum level.
DB00279
Baclofen may decrease the excretion rate of Liothyronine which could result in a higher serum level.
DB00286
Baclofen may decrease the excretion rate of Conjugated estrogens which could result in a higher serum level.
DB00290
Baclofen may decrease the excretion rate of Bleomycin which could result in a higher serum level.
DB00294
Baclofen may decrease the excretion rate of Etonogestrel which could result in a higher serum level.
DB00296
Baclofen may decrease the excretion rate of Ropivacaine which could result in a higher serum level.
DB00303
Baclofen may decrease the excretion rate of Ertapenem which could result in a higher serum level.
DB00308
Baclofen may decrease the excretion rate of Ibutilide which could result in a higher serum level.
DB00316
Baclofen may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
DB00319
Baclofen may decrease the excretion rate of Piperacillin which could result in a higher serum level.
DB00322
Baclofen may decrease the excretion rate of Floxuridine which could result in a higher serum level.
DB00330
Baclofen may decrease the excretion rate of Ethambutol which could result in a higher serum level.
DB00339
Baclofen may decrease the excretion rate of Pyrazinamide which could result in a higher serum level.
DB00351
Baclofen may decrease the excretion rate of Megestrol acetate which could result in a higher serum level.
DB00355
Baclofen may decrease the excretion rate of Aztreonam which could result in a higher serum level.
DB00364
Baclofen may decrease the excretion rate of Sucralfate which could result in a higher serum level.
DB00380
Baclofen may decrease the excretion rate of Dexrazoxane which could result in a higher serum level.
DB00398
Baclofen may decrease the excretion rate of Sorafenib which could result in a higher serum level.
DB00415
Baclofen may decrease the excretion rate of Ampicillin which could result in a higher serum level.
DB00422
Baclofen may decrease the excretion rate of Methylphenidate which could result in a higher serum level.
DB00432
Baclofen may decrease the excretion rate of Trifluridine which could result in a higher serum level.
DB00435
Baclofen may decrease the excretion rate of Nitric Oxide which could result in a higher serum level.
DB00437
Baclofen may decrease the excretion rate of Allopurinol which could result in a higher serum level.
DB00441
Baclofen may decrease the excretion rate of Gemcitabine which could result in a higher serum level.
DB00480
Baclofen may decrease the excretion rate of Lenalidomide which could result in a higher serum level.
DB00490
Baclofen may decrease the excretion rate of Buspirone which could result in a higher serum level.
DB00499
Baclofen may decrease the excretion rate of Flutamide which could result in a higher serum level.
DB00535
Baclofen may decrease the excretion rate of Cefdinir which could result in a higher serum level.
DB00548
Baclofen may decrease the excretion rate of Azelaic acid which could result in a higher serum level.
DB00553
Baclofen may decrease the excretion rate of Methoxsalen which could result in a higher serum level.
DB00558
Baclofen may decrease the excretion rate of Zanamivir which could result in a higher serum level.
DB00569
Baclofen may decrease the excretion rate of Fondaparinux which could result in a higher serum level.
DB00583
Baclofen may decrease the excretion rate of Levocarnitine which could result in a higher serum level.
DB00591
Baclofen may decrease the excretion rate of Fluocinolone acetonide which could result in a higher serum level.
DB00597
Baclofen may decrease the excretion rate of Gadoteridol which could result in a higher serum level.
DB00603
Baclofen may decrease the excretion rate of Medroxyprogesterone acetate which could result in a higher serum level.
DB00624
Baclofen may decrease the excretion rate of Testosterone which could result in a higher serum level.
DB00631
Baclofen may decrease the excretion rate of Clofarabine which could result in a higher serum level.
DB00635
Baclofen may decrease the excretion rate of Prednisone which could result in a higher serum level.
DB00651
Baclofen may decrease the excretion rate of Dyphylline which could result in a higher serum level.
DB00661
Baclofen may decrease the excretion rate of Verapamil which could result in a higher serum level.
DB00665
Baclofen may decrease the excretion rate of Nilutamide which could result in a higher serum level.
DB00698
Baclofen may decrease the excretion rate of Nitrofurantoin which could result in a higher serum level.
DB00706
Baclofen may decrease the excretion rate of Tamsulosin which could result in a higher serum level.
DB00713
Baclofen may decrease the excretion rate of Oxacillin which could result in a higher serum level.
DB00716
Baclofen may decrease the excretion rate of Nedocromil which could result in a higher serum level.
DB00730
Baclofen may decrease the excretion rate of Thiabendazole which could result in a higher serum level.
DB00733
Baclofen may decrease the excretion rate of Pralidoxime which could result in a higher serum level.
DB00743
Baclofen may decrease the excretion rate of Gadobenic acid which could result in a higher serum level.
DB00759
Baclofen may decrease the excretion rate of Tetracycline which could result in a higher serum level.
DB00760
Baclofen may decrease the excretion rate of Meropenem which could result in a higher serum level.
DB00761
Baclofen may decrease the excretion rate of Potassium chloride which could result in a higher serum level.
DB00763
Baclofen may decrease the excretion rate of Methimazole which could result in a higher serum level.
DB00775
Baclofen may decrease the excretion rate of Tirofiban which could result in a higher serum level.
DB00783
Baclofen may decrease the excretion rate of Estradiol which could result in a higher serum level.
DB00789
Baclofen may decrease the excretion rate of Gadopentetic acid which could result in a higher serum level.
DB00806
Baclofen may decrease the excretion rate of Pentoxifylline which could result in a higher serum level.
DB00811
Baclofen may decrease the excretion rate of Ribavirin which could result in a higher serum level.
DB00828
Baclofen may decrease the excretion rate of Fosfomycin which could result in a higher serum level.
DB00841
Baclofen may decrease the excretion rate of Dobutamine which could result in a higher serum level.
DB00851
Baclofen may decrease the excretion rate of Dacarbazine which could result in a higher serum level.
DB00853
Baclofen may decrease the excretion rate of Temozolomide which could result in a higher serum level.
DB00871
Baclofen may decrease the excretion rate of Terbutaline which could result in a higher serum level.
DB00894
Baclofen may decrease the excretion rate of Testolactone which could result in a higher serum level.
DB00900
Baclofen may decrease the excretion rate of Didanosine which could result in a higher serum level.
DB00911
Baclofen may decrease the excretion rate of Tinidazole which could result in a higher serum level.
DB00915
Baclofen may decrease the excretion rate of Amantadine which could result in a higher serum level.
DB00928
Baclofen may decrease the excretion rate of Azacitidine which could result in a higher serum level.
DB00961
Baclofen may decrease the excretion rate of Mepivacaine which could result in a higher serum level.
DB00988
Baclofen may decrease the excretion rate of Dopamine which could result in a higher serum level.
DB00993
Baclofen may decrease the excretion rate of Azathioprine which could result in a higher serum level.
DB00995
Baclofen may decrease the excretion rate of Auranofin which could result in a higher serum level.
DB01001
Baclofen may decrease the excretion rate of Salbutamol which could result in a higher serum level.
DB01002
Baclofen may decrease the excretion rate of Levobupivacaine which could result in a higher serum level.
DB01010
Baclofen may decrease the excretion rate of Edrophonium which could result in a higher serum level.
DB01011
Baclofen may decrease the excretion rate of Metyrapone which could result in a higher serum level.
DB01020
Baclofen may decrease the excretion rate of Isosorbide mononitrate which could result in a higher serum level.
DB01022
Baclofen may decrease the excretion rate of Phylloquinone which could result in a higher serum level.
DB01024
Baclofen may decrease the excretion rate of Mycophenolic acid which could result in a higher serum level.
DB01030
Baclofen may decrease the excretion rate of Topotecan which could result in a higher serum level.
DB01032
Baclofen may decrease the excretion rate of Probenecid which could result in a higher serum level.
DB01043
Baclofen may decrease the excretion rate of Memantine which could result in a higher serum level.
DB01046
Baclofen may decrease the excretion rate of Lubiprostone which could result in a higher serum level.
DB01048
Baclofen may decrease the excretion rate of Abacavir which could result in a higher serum level.
DB01060
Baclofen may decrease the excretion rate of Amoxicillin which could result in a higher serum level.
DB01093
Baclofen may decrease the excretion rate of Dimethyl sulfoxide which could result in a higher serum level.
DB01099
Baclofen may decrease the excretion rate of Flucytosine which could result in a higher serum level.
DB01101
Baclofen may decrease the excretion rate of Capecitabine which could result in a higher serum level.
DB01115
Baclofen may decrease the excretion rate of Nifedipine which could result in a higher serum level.
DB01129
Baclofen may decrease the excretion rate of Rabeprazole which could result in a higher serum level.
DB01133
Baclofen may decrease the excretion rate of Tiludronic acid which could result in a higher serum level.
DB01137
Baclofen may decrease the excretion rate of Levofloxacin which could result in a higher serum level.
DB01157
Baclofen may decrease the excretion rate of Trimetrexate which could result in a higher serum level.
DB01166
Baclofen may decrease the excretion rate of Cilostazol which could result in a higher serum level.
DB01169
Baclofen may decrease the excretion rate of Arsenic trioxide which could result in a higher serum level.
DB01181
Baclofen may decrease the excretion rate of Ifosfamide which could result in a higher serum level.
DB01183
Baclofen may decrease the excretion rate of Naloxone which could result in a higher serum level.
DB01205
Baclofen may decrease the excretion rate of Flumazenil which could result in a higher serum level.
DB01213
Baclofen may decrease the excretion rate of Fomepizole which could result in a higher serum level.
DB01222
Baclofen may decrease the excretion rate of Budesonide which could result in a higher serum level.
DB01249
Baclofen may decrease the excretion rate of Iodixanol which could result in a higher serum level.
DB01273
Baclofen may decrease the excretion rate of Varenicline which could result in a higher serum level.
DB01274
Baclofen may decrease the excretion rate of Arformoterol which could result in a higher serum level.
DB01420
Baclofen may decrease the excretion rate of Testosterone propionate which could result in a higher serum level.
DB01427
Baclofen may decrease the excretion rate of Amrinone which could result in a higher serum level.
DB01428
Baclofen may decrease the excretion rate of Oxybenzone which could result in a higher serum level.
DB01431
Baclofen may decrease the excretion rate of Allylestrenol which could result in a higher serum level.
DB01550
Baclofen may decrease the excretion rate of Fenproporex which could result in a higher serum level.
DB01610
Baclofen may decrease the excretion rate of Valganciclovir which could result in a higher serum level.
DB01638
Baclofen may decrease the excretion rate of Sorbitol which could result in a higher serum level.
DB01656
Baclofen may decrease the excretion rate of Roflumilast which could result in a higher serum level.
DB01685
Baclofen may decrease the excretion rate of Topiroxostat which could result in a higher serum level.
DB04574
Baclofen may decrease the excretion rate of Estrone sulfate which could result in a higher serum level.
DB04895
Baclofen may decrease the excretion rate of Pegaptanib which could result in a higher serum level.
DB04920
Baclofen may decrease the excretion rate of Clevidipine which could result in a higher serum level.
DB05018
Baclofen may decrease the excretion rate of Migalastat which could result in a higher serum level.
DB05676
Baclofen may decrease the excretion rate of Apremilast which could result in a higher serum level.
DB06154
Baclofen may decrease the excretion rate of Pentaerythritol tetranitrate which could result in a higher serum level.
DB06186
Baclofen may decrease the excretion rate of Ipilimumab which could result in a higher serum level.
DB06196
Baclofen may decrease the excretion rate of Icatibant which could result in a higher serum level.
DB06209
Baclofen may decrease the excretion rate of Prasugrel which could result in a higher serum level.
DB06211
Baclofen may decrease the excretion rate of Doripenem which could result in a higher serum level.
DB06228
Baclofen may decrease the excretion rate of Rivaroxaban which could result in a higher serum level.
DB06230
Baclofen may decrease the excretion rate of Nalmefene which could result in a higher serum level.
DB06262
Baclofen may decrease the excretion rate of Droxidopa which could result in a higher serum level.
DB06402
Baclofen may decrease the excretion rate of Telavancin which could result in a higher serum level.
DB06480
Baclofen may decrease the excretion rate of Prucalopride which could result in a higher serum level.
DB06623
Baclofen may decrease the excretion rate of Flupirtine which could result in a higher serum level.
DB06637
Baclofen may decrease the excretion rate of Dalfampridine which could result in a higher serum level.
DB06695
Baclofen may decrease the excretion rate of Dabigatran etexilate which could result in a higher serum level.
DB06705
Baclofen may decrease the excretion rate of Gadofosveset trisodium which could result in a higher serum level.
DB06710
Baclofen may decrease the excretion rate of Methyltestosterone which could result in a higher serum level.
DB06767
Baclofen may decrease the excretion rate of Ammonium chloride which could result in a higher serum level.
DB06782
Baclofen may decrease the excretion rate of Dimercaprol which could result in a higher serum level.
DB06796
Baclofen may decrease the excretion rate of Mangafodipir which could result in a higher serum level.
DB06800
Baclofen may decrease the excretion rate of Methylnaltrexone which could result in a higher serum level.
DB06809
Baclofen may decrease the excretion rate of Plerixafor which could result in a higher serum level.
DB06813
Baclofen may decrease the excretion rate of Pralatrexate which could result in a higher serum level.
DB06823
Baclofen may decrease the excretion rate of Tiopronin which could result in a higher serum level.
DB06824
Baclofen may decrease the excretion rate of Triethylenetetramine which could result in a higher serum level.
DB08824
Baclofen may decrease the excretion rate of Ioflupane I-123 which could result in a higher serum level.
DB08826
Baclofen may decrease the excretion rate of Deferiprone which could result in a higher serum level.
DB08840
Baclofen may decrease the excretion rate of N-methylnicotinamide which could result in a higher serum level.
DB08877
Baclofen may decrease the excretion rate of Ruxolitinib which could result in a higher serum level.
DB08893
Baclofen may decrease the excretion rate of Mirabegron which could result in a higher serum level.
DB08894
Baclofen may decrease the excretion rate of Peginesatide which could result in a higher serum level.
DB08899
Baclofen may decrease the excretion rate of Enzalutamide which could result in a higher serum level.
DB08900
Baclofen may decrease the excretion rate of Teduglutide which could result in a higher serum level.
DB08904
Baclofen may decrease the excretion rate of Certolizumab pegol which could result in a higher serum level.
DB08905
Baclofen may decrease the excretion rate of Formestane which could result in a higher serum level.
DB08909
Baclofen may decrease the excretion rate of Glycerol phenylbutyrate which could result in a higher serum level.
DB08911
Baclofen may decrease the excretion rate of Trametinib which could result in a higher serum level.
DB08934
Baclofen may decrease the excretion rate of Sofosbuvir which could result in a higher serum level.
DB09027
Baclofen may decrease the excretion rate of Ledipasvir which could result in a higher serum level.
DB09050
Baclofen may decrease the excretion rate of Ceftolozane which could result in a higher serum level.
DB09066
Baclofen may decrease the excretion rate of Corifollitropin alfa which could result in a higher serum level.
DB09075
Baclofen may decrease the excretion rate of Edoxaban which could result in a higher serum level.
DB09081
Baclofen may decrease the excretion rate of Idebenone which could result in a higher serum level.
DB09082
Baclofen may decrease the excretion rate of Vilanterol which could result in a higher serum level.
DB09091
Baclofen may decrease the excretion rate of Tixocortol which could result in a higher serum level.
DB09103
Baclofen may decrease the excretion rate of Ancestim which could result in a higher serum level.
DB09104
Baclofen may decrease the excretion rate of Magnesium hydroxide which could result in a higher serum level.
DB09106
Baclofen may decrease the excretion rate of Hydroxyethyl Starch which could result in a higher serum level.
DB09111
Baclofen may decrease the excretion rate of Pentastarch which could result in a higher serum level.
DB09121
Baclofen may decrease the excretion rate of Aurothioglucose which could result in a higher serum level.
DB09123
Baclofen may decrease the excretion rate of Dienogest which could result in a higher serum level.
DB09129
Baclofen may decrease the excretion rate of Chromic chloride which could result in a higher serum level.
DB09132
Baclofen may decrease the excretion rate of Gadoteric acid which could result in a higher serum level.
DB09133
Baclofen may decrease the excretion rate of Iothalamic acid which could result in a higher serum level.
DB09134
Baclofen may decrease the excretion rate of Ioversol which could result in a higher serum level.
DB09135
Baclofen may decrease the excretion rate of Ioxilan which could result in a higher serum level.
DB09136
Baclofen may decrease the excretion rate of Isosulfan blue which could result in a higher serum level.
DB09137
Baclofen may decrease the excretion rate of Technetium Tc-99m mebrofenin which could result in a higher serum level.
DB09139
Baclofen may decrease the excretion rate of Technetium Tc-99m oxidronate which could result in a higher serum level.
DB09148
Baclofen may decrease the excretion rate of Florbetaben (18F) which could result in a higher serum level.
DB09149
Baclofen may decrease the excretion rate of Florbetapir (18F) which could result in a higher serum level.
DB09156
Baclofen may decrease the excretion rate of Iopromide which could result in a higher serum level.
DB09163
Baclofen may decrease the excretion rate of Technetium Tc-99m exametazime which could result in a higher serum level.
DB09165
Baclofen may decrease the excretion rate of Technetium Tc-99m pyrophosphate which could result in a higher serum level.
DB09204
Baclofen may decrease the excretion rate of Arotinolol which could result in a higher serum level.
DB09205
Baclofen may decrease the excretion rate of Moxisylyte which could result in a higher serum level.
DB09209
Baclofen may decrease the excretion rate of Pholcodine which could result in a higher serum level.
DB09210
Baclofen may decrease the excretion rate of Piracetam which could result in a higher serum level.
DB09219
Baclofen may decrease the excretion rate of Bisoxatin which could result in a higher serum level.
DB09255
Baclofen may decrease the excretion rate of Dextran which could result in a higher serum level.
DB09256
Baclofen may decrease the excretion rate of Tegafur which could result in a higher serum level.
DB09257
Baclofen may decrease the excretion rate of Gimeracil which could result in a higher serum level.
DB09264
Baclofen may decrease the excretion rate of Idarucizumab which could result in a higher serum level.
DB09268
Baclofen may decrease the excretion rate of Picosulfuric acid which could result in a higher serum level.
DB09276
Baclofen may decrease the excretion rate of Sodium aurothiomalate which could result in a higher serum level.
DB09277
Baclofen may decrease the excretion rate of Choline C 11 which could result in a higher serum level.
DB09281
Baclofen may decrease the excretion rate of Magnesium trisilicate which could result in a higher serum level.
DB09292
Baclofen may decrease the excretion rate of Sacubitril which could result in a higher serum level.
DB09301
Baclofen may decrease the excretion rate of Chondroitin sulfate which could result in a higher serum level.
DB09317
Baclofen may decrease the excretion rate of Synthetic Conjugated Estrogens, A which could result in a higher serum level.
DB09318
Baclofen may decrease the excretion rate of Synthetic Conjugated Estrogens, B which could result in a higher serum level.
DB09320
Baclofen may decrease the excretion rate of Procaine benzylpenicillin which could result in a higher serum level.
DB09324
Baclofen may decrease the excretion rate of Sulbactam which could result in a higher serum level.
DB09325
Baclofen may decrease the excretion rate of Sodium fluoride which could result in a higher serum level.
DB09329
Baclofen may decrease the excretion rate of Antihemophilic Factor (Recombinant), PEGylated which could result in a higher serum level.
DB09344
Baclofen may decrease the excretion rate of Invert sugar which could result in a higher serum level.
DB09357
Baclofen may decrease the excretion rate of Dexpanthenol which could result in a higher serum level.
DB09394
Baclofen may decrease the excretion rate of Phosphoric acid which could result in a higher serum level.
DB09395
Baclofen may decrease the excretion rate of Sodium acetate which could result in a higher serum level.
DB09407
Baclofen may decrease the excretion rate of Magnesium chloride which could result in a higher serum level.
DB09418
Baclofen may decrease the excretion rate of Potassium perchlorate which could result in a higher serum level.
DB09472
Baclofen may decrease the excretion rate of Sodium sulfate which could result in a higher serum level.
DB09481
Baclofen may decrease the excretion rate of Magnesium carbonate which could result in a higher serum level.
DB09488
Baclofen may decrease the excretion rate of Acrivastine which could result in a higher serum level.
DB09496
Baclofen may decrease the excretion rate of Octinoxate which could result in a higher serum level.
DB09502
Baclofen may decrease the excretion rate of Fludeoxyglucose (18F) which could result in a higher serum level.
DB09546
Baclofen may decrease the excretion rate of Iobenguane sulfate I-123 which could result in a higher serum level.
DB09570
Baclofen may decrease the excretion rate of Ixazomib which could result in a higher serum level.
DB11077
Baclofen may decrease the excretion rate of Polyethylene glycol 400 which could result in a higher serum level.
DB11090
Baclofen may decrease the excretion rate of Potassium nitrate which could result in a higher serum level.
DB11098
Baclofen may decrease the excretion rate of Potassium bicarbonate which could result in a higher serum level.
DB11102
Baclofen may decrease the excretion rate of N-acetyltyrosine which could result in a higher serum level.
DB11114
Baclofen may decrease the excretion rate of Eucalyptus oil which could result in a higher serum level.
DB11127
Baclofen may decrease the excretion rate of Selenious acid which could result in a higher serum level.
DB11135
Baclofen may decrease the excretion rate of Selenium which could result in a higher serum level.
DB11136
Baclofen may decrease the excretion rate of Chromium which could result in a higher serum level.
DB11145
Baclofen may decrease the excretion rate of Oxyquinoline which could result in a higher serum level.
DB11164
Baclofen may decrease the excretion rate of Bicisate which could result in a higher serum level.
DB11251
Baclofen may decrease the excretion rate of Tocopherol which could result in a higher serum level.
DB11278
Baclofen may decrease the excretion rate of DL-Methylephedrine which could result in a higher serum level.
DB11328
Baclofen may decrease the excretion rate of Tetradecyl hydrogen sulfate (ester) which could result in a higher serum level.
DB11338
Baclofen may decrease the excretion rate of Clove oil which could result in a higher serum level.
DB11358
Baclofen may decrease the excretion rate of Evening primrose oil which could result in a higher serum level.
DB11364
Baclofen may decrease the excretion rate of Pidotimod which could result in a higher serum level.
DB11560
Baclofen may decrease the excretion rate of Lesinurad which could result in a higher serum level.
DB11577
Baclofen may decrease the excretion rate of Indigotindisulfonic acid which could result in a higher serum level.
DB11587
Baclofen may decrease the excretion rate of Etafedrine which could result in a higher serum level.
DB11598
Baclofen may decrease the excretion rate of Antithrombin III human which could result in a higher serum level.
DB11642
Baclofen may decrease the excretion rate of Pitolisant which could result in a higher serum level.
DB11691
Baclofen may decrease the excretion rate of Naldemedine which could result in a higher serum level.
DB11817
Baclofen may decrease the excretion rate of Baricitinib which could result in a higher serum level.
DB11901
Baclofen may decrease the excretion rate of Apalutamide which could result in a higher serum level.
DB11915
Baclofen may decrease the excretion rate of Valbenazine which could result in a higher serum level.
DB11943
Baclofen may decrease the excretion rate of Delafloxacin which could result in a higher serum level.
DB11989
Baclofen may decrease the excretion rate of Benznidazole which could result in a higher serum level.
DB12007
Baclofen may decrease the excretion rate of Isoflavone which could result in a higher serum level.
DB12107
Baclofen may decrease the excretion rate of Vaborbactam which could result in a higher serum level.
DB12161
Baclofen may decrease the excretion rate of Deutetrabenazine which could result in a higher serum level.
DB12783
Baclofen may decrease the excretion rate of Benserazide which could result in a higher serum level.
DB13139
Baclofen may decrease the excretion rate of Levosalbutamol which could result in a higher serum level.
DB13156
Baclofen may decrease the excretion rate of Inosine pranobex which could result in a higher serum level.
DB13178
Baclofen may decrease the excretion rate of Inositol which could result in a higher serum level.
DB13185
Baclofen may decrease the excretion rate of Oxabolone cipionate which could result in a higher serum level.
DB13191
Baclofen may decrease the excretion rate of Phosphocreatine which could result in a higher serum level.
DB13269
Baclofen may decrease the excretion rate of Dichlorobenzyl alcohol which could result in a higher serum level.
DB13595
Baclofen may decrease the excretion rate of Almasilate which could result in a higher serum level.
DB13884
Baclofen may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
DB13909
Baclofen may decrease the excretion rate of Bismuth subgallate which could result in a higher serum level.
DB13943
Baclofen may decrease the excretion rate of Testosterone cypionate which could result in a higher serum level.
DB13944
Baclofen may decrease the excretion rate of Testosterone enanthate which could result in a higher serum level.
DB13946
Baclofen may decrease the excretion rate of Testosterone undecanoate which could result in a higher serum level.
DB13952
Baclofen may decrease the excretion rate of Estradiol acetate which could result in a higher serum level.
DB13954
Baclofen may decrease the excretion rate of Estradiol cypionate which could result in a higher serum level.
DB13955
Baclofen may decrease the excretion rate of Estradiol dienanthate which could result in a higher serum level.
DB13956
Baclofen may decrease the excretion rate of Estradiol valerate which could result in a higher serum level.
DB13967
Baclofen may decrease the excretion rate of Patent Blue which could result in a higher serum level.
DB14006
Baclofen may decrease the excretion rate of Choline salicylate which could result in a higher serum level.
DB14007
Baclofen may decrease the excretion rate of Pentetic acid which could result in a higher serum level.
DB14498
Baclofen may decrease the excretion rate of Potassium acetate which could result in a higher serum level.
DB14499
Baclofen may decrease the excretion rate of Potassium sulfate which could result in a higher serum level.
DB14526
Baclofen may decrease the excretion rate of Chromic citrate which could result in a higher serum level.
DB14527
Baclofen may decrease the excretion rate of Chromic nitrate which could result in a higher serum level.
DB14528
Baclofen may decrease the excretion rate of Chromium gluconate which could result in a higher serum level.
DB14529
Baclofen may decrease the excretion rate of Chromium nicotinate which could result in a higher serum level.
DB14530
Baclofen may decrease the excretion rate of Chromous sulfate which could result in a higher serum level.
DB06815
Baclofen may decrease the excretion rate of Pyrithione which could result in a higher serum level.
DB11121
Baclofen may decrease the excretion rate of Chloroxylenol which could result in a higher serum level.
DB11085
Baclofen may decrease the excretion rate of Resorcinol which could result in a higher serum level.
DB15593
Baclofen may decrease the excretion rate of Golodirsen which could result in a higher serum level.
DB00879
Baclofen may decrease the excretion rate of Emtricitabine which could result in a higher serum level.
DB13987
Baclofen may decrease the excretion rate of Strontium chloride which could result in a higher serum level.
DB04890
Baclofen may decrease the excretion rate of Bepotastine which could result in a higher serum level.
DB04930
Baclofen may decrease the excretion rate of Permethrin which could result in a higher serum level.
DB09095
Baclofen may decrease the excretion rate of Difluocortolone which could result in a higher serum level.
DB00552
Baclofen may decrease the excretion rate of Pentostatin which could result in a higher serum level.
DB13145
Baclofen may decrease the excretion rate of Nedaplatin which could result in a higher serum level.
DB00390
Baclofen may decrease the excretion rate of Digoxin which could result in a higher serum level.
DB00564
Baclofen may decrease the excretion rate of Carbamazepine which could result in a higher serum level.
DB00642
Baclofen may decrease the excretion rate of Pemetrexed which could result in a higher serum level.
DB00682
Baclofen may decrease the excretion rate of Warfarin which could result in a higher serum level.
DB00908
Baclofen may decrease the excretion rate of Quinidine which could result in a higher serum level.
DB01035
Baclofen may decrease the excretion rate of Procainamide which could result in a higher serum level.
DB09338
Baclofen may increase the excretion rate of Mersalyl which could result in a lower serum level and potentially a reduction in efficacy.
DB00232
Methyclothiazide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB00311
Ethoxzolamide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB00421
Spironolactone may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB00562
Benzthiazide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB00594
Amiloride may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB00703
Methazolamide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB00872
Conivaptan may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB01144
Diclofenamide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB01325
Quinethazone may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB01395
Drospirenone may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB01412
Theobromine may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB02925
Piretanide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB05034
Ularitide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB06212
Tolvaptan may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB06370
Indisulam may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB08961
Azosemide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB09015
Canrenoic acid may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB09125
Potassium citrate may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB09401
Isosorbide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB12221
Canrenone may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB12670
Rolofylline may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB12704
Spiradoline may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB13284
Meticrane may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB13405
Mefruside may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB13430
Mebutizide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB13617
Clorexolone may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB13663
Clofenamide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB13708
Fenquizone may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB13792
Clopamide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB13989
Epitizide may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB14018
Bromotheophylline may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB14500
Potassium may increase the excretion rate of Baclofen which could result in a lower serum level and potentially a reduction in efficacy.
DB01345
Baclofen may increase the excretion rate of Potassium cation which could result in a lower serum level and potentially a reduction in efficacy.
DB00007
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Leuprolide is combined with Baclofen.
DB00052
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Somatotropin is combined with Baclofen.
DB00065
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Infliximab is combined with Baclofen.
DB00080
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Daptomycin is combined with Baclofen.
DB00175
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Pravastatin is combined with Baclofen.
DB00203
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Sildenafil.
DB00224
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Indinavir.
DB00227
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Lovastatin.
DB00242
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Cladribine.
DB00358
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Mefloquine.
DB00382
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Tacrine.
DB00389
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Carbimazole.
DB00439
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Cerivastatin.
DB00440
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Trimethoprim.
DB00443
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Betamethasone.
DB00471
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Montelukast.
DB00495
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Zidovudine.
DB00501
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Cimetidine.
DB00503
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ritonavir.
DB00537
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ciprofloxacin.
DB00541
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Vincristine.
DB00550
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Propylthiouracil.
DB00585
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Nizatidine.
DB00602
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ivermectin.
DB00608
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Chloroquine.
DB00620
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Triamcinolone.
DB00627
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Niacin.
DB00630
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Alendronic acid.
DB00636
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Clofibrate.
DB00641
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Simvastatin.
DB00649
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Stavudine.
DB00666
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Nafarelin.
DB00688
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Mycophenolate mofetil.
DB00704
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Naltrexone.
DB00709
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Lamivudine.
DB00710
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ibandronate.
DB00857
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Terbinafine.
DB00859
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Penicillamine.
DB00863
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ranitidine.
DB00884
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Risedronic acid.
DB00938
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Salmeterol.
DB00951
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Isoniazid.
DB00987
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Cytarabine.
DB01004
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ganciclovir.
DB01006
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Letrozole.
DB01039
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Fenofibrate.
DB01059
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Norfloxacin.
DB01076
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Atorvastatin.
DB01088
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Iloprost.
DB01095
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Fluvastatin.
DB01097
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Leflunomide.
DB01118
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Amiodarone.
DB01165
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ofloxacin.
DB01229
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Paclitaxel.
DB01232
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Saquinavir.
DB01234
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Dexamethasone.
DB01241
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Gemfibrozil.
DB01248
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Docetaxel.
DB01393
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Bezafibrate.
DB01394
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Colchicine.
DB02703
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Fusidic acid.
DB05109
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Trabectedin.
DB06693
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Mevastatin.
DB06817
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Raltegravir.
DB08860
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Pitavastatin.
DB08983
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Etofibrate.
DB09055
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Acipimox.
DB09064
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ciprofibrate.
DB09270
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ubidecarenone.
DB12554
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Mebeverine.
DB13293
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ipecac.
DB13393
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Emetine.
DB13433
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Simfibrate.
DB13460
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Ronifibrate.
DB13780
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Aluminium clofibrate.
DB13849
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Clofibride.
DB13873
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Fenofibric acid.
DB01098
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Rosuvastatin.
DB00982
The risk or severity of myopathy, rhabdomyolysis, and myoglobinuria can be increased when Baclofen is combined with Isotretinoin.
DB05077
The risk or severity of adverse effects can be increased when SLV319 is combined with Baclofen.
DB06155
The risk or severity of adverse effects can be increased when Rimonabant is combined with Baclofen.
DB06624
The risk or severity of adverse effects can be increased when Taranabant is combined with Baclofen.
DB09061
The risk or severity of adverse effects can be increased when Cannabidiol is combined with Baclofen.
DB11903
The risk or severity of adverse effects can be increased when GW842166 is combined with Baclofen.
DB12193
The risk or severity of adverse effects can be increased when Ajulemic acid is combined with Baclofen.
DB12649
The risk or severity of adverse effects can be increased when Ibipinabant is combined with Baclofen.
DB13070
The risk or severity of adverse effects can be increased when Surinabant is combined with Baclofen.
DB13950
The risk or severity of adverse effects can be increased when WIN 55212-2 is combined with Baclofen.
DB14011
The risk or severity of adverse effects can be increased when Nabiximols is combined with Baclofen.
DB14043
The risk or severity of adverse effects can be increased when Palmidrol is combined with Baclofen.
DB14737
The risk or severity of adverse effects can be increased when Cannabinol is combined with Baclofen.
DB00177
The risk or severity of adverse effects can be increased when Baclofen is combined with Valsartan.
DB00178
The risk or severity of adverse effects can be increased when Baclofen is combined with Ramipril.
DB00187
The risk or severity of adverse effects can be increased when Baclofen is combined with Esmolol.
DB00195
The risk or severity of adverse effects can be increased when Baclofen is combined with Betaxolol.
DB00206
The risk or severity of adverse effects can be increased when Baclofen is combined with Reserpine.
DB00212
The risk or severity of adverse effects can be increased when Baclofen is combined with Remikiren.
DB00214
The risk or severity of adverse effects can be increased when Baclofen is combined with Torasemide.
DB00217
The risk or severity of adverse effects can be increased when Baclofen is combined with Bethanidine.
DB00226
The risk or severity of adverse effects can be increased when Baclofen is combined with Guanadrel.
DB00264
The risk or severity of adverse effects can be increased when Baclofen is combined with Metoprolol.
DB00270
The risk or severity of adverse effects can be increased when Baclofen is combined with Isradipine.
DB00275
The risk or severity of adverse effects can be increased when Baclofen is combined with Olmesartan.
DB00310
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorthalidone.
DB00325
The risk or severity of adverse effects can be increased when Baclofen is combined with Nitroprusside.
DB00335
The risk or severity of adverse effects can be increased when Baclofen is combined with Atenolol.
DB00343
The risk or severity of adverse effects can be increased when Baclofen is combined with Diltiazem.
DB00350
The risk or severity of adverse effects can be increased when Baclofen is combined with Minoxidil.
DB00373
The risk or severity of adverse effects can be increased when Baclofen is combined with Timolol.
DB00374
The risk or severity of adverse effects can be increased when Baclofen is combined with Treprostinil.
DB00381
The risk or severity of adverse effects can be increased when Baclofen is combined with Amlodipine.
DB00393
The risk or severity of adverse effects can be increased when Baclofen is combined with Nimodipine.
DB00401
The risk or severity of adverse effects can be increased when Baclofen is combined with Nisoldipine.
DB00436
The risk or severity of adverse effects can be increased when Baclofen is combined with Bendroflumethiazide.
DB00457
The risk or severity of adverse effects can be increased when Baclofen is combined with Prazosin.
DB00492
The risk or severity of adverse effects can be increased when Baclofen is combined with Fosinopril.
DB00519
The risk or severity of adverse effects can be increased when Baclofen is combined with Trandolapril.
DB00524
The risk or severity of adverse effects can be increased when Baclofen is combined with Metolazone.
DB00528
The risk or severity of adverse effects can be increased when Baclofen is combined with Lercanidipine.
DB00542
The risk or severity of adverse effects can be increased when Baclofen is combined with Benazepril.
DB00559
The risk or severity of adverse effects can be increased when Baclofen is combined with Bosentan.
DB00571
The risk or severity of adverse effects can be increased when Baclofen is combined with Propranolol.
DB00584
The risk or severity of adverse effects can be increased when Baclofen is combined with Enalapril.
DB00590
The risk or severity of adverse effects can be increased when Baclofen is combined with Doxazosin.
DB00598
The risk or severity of adverse effects can be increased when Baclofen is combined with Labetalol.
DB00606
The risk or severity of adverse effects can be increased when Baclofen is combined with Cyclothiazide.
DB00612
The risk or severity of adverse effects can be increased when Baclofen is combined with Bisoprolol.
DB00616
The risk or severity of adverse effects can be increased when Baclofen is combined with Candoxatril.
DB00622
The risk or severity of adverse effects can be increased when Baclofen is combined with Nicardipine.
DB00629
The risk or severity of adverse effects can be increased when Baclofen is combined with Guanabenz.
DB00657
The risk or severity of adverse effects can be increased when Baclofen is combined with Mecamylamine.
DB00678
The risk or severity of adverse effects can be increased when Baclofen is combined with Losartan.
DB00691
The risk or severity of adverse effects can be increased when Baclofen is combined with Moexipril.
DB00692
The risk or severity of adverse effects can be increased when Baclofen is combined with Phentolamine.
DB00700
The risk or severity of adverse effects can be increased when Baclofen is combined with Eplerenone.
DB00722
The risk or severity of adverse effects can be increased when Baclofen is combined with Lisinopril.
DB00727
The risk or severity of adverse effects can be increased when Baclofen is combined with Nitroglycerin.
DB00765
The risk or severity of adverse effects can be increased when Baclofen is combined with Metyrosine.
DB00774
The risk or severity of adverse effects can be increased when Baclofen is combined with Hydroflumethiazide.
DB00785
The risk or severity of adverse effects can be increased when Baclofen is combined with Cryptenamine.
DB00790
The risk or severity of adverse effects can be increased when Baclofen is combined with Perindopril.
DB00796
The risk or severity of adverse effects can be increased when Baclofen is combined with Candesartan cilexetil.
DB00797
The risk or severity of adverse effects can be increased when Baclofen is combined with Tolazoline.
DB00800
The risk or severity of adverse effects can be increased when Baclofen is combined with Fenoldopam.
DB00808
The risk or severity of adverse effects can be increased when Baclofen is combined with Indapamide.
DB00820
The risk or severity of adverse effects can be increased when Baclofen is combined with Tadalafil.
DB00866
The risk or severity of adverse effects can be increased when Baclofen is combined with Alprenolol.
DB00876
The risk or severity of adverse effects can be increased when Baclofen is combined with Eprosartan.
DB00880
The risk or severity of adverse effects can be increased when Baclofen is combined with Chlorothiazide.
DB00881
The risk or severity of adverse effects can be increased when Baclofen is combined with Quinapril.
DB00886
The risk or severity of adverse effects can be increased when Baclofen is combined with Omapatrilat.
DB00925
The risk or severity of adverse effects can be increased when Baclofen is combined with Phenoxybenzamine.
DB00960
The risk or severity of adverse effects can be increased when Baclofen is combined with Pindolol.
DB00966
The risk or severity of adverse effects can be increased when Baclofen is combined with Telmisartan.
DB00968
The risk or severity of adverse effects can be increased when Baclofen is combined with Methyldopa.
DB00999
The risk or severity of adverse effects can be increased when Baclofen is combined with Hydrochlorothiazide.
DB01018
The risk or severity of adverse effects can be increased when Baclofen is combined with Guanfacine.
DB01021
The risk or severity of adverse effects can be increased when Baclofen is combined with Trichlormethiazide.
DB01023
The risk or severity of adverse effects can be increased when Baclofen is combined with Felodipine.
DB01029
The risk or severity of adverse effects can be increased when Baclofen is combined with Irbesartan.
DB01054
The risk or severity of adverse effects can be increased when Baclofen is combined with Nitrendipine.
DB01089
The risk or severity of adverse effects can be increased when Baclofen is combined with Deserpidine.
DB01090
The risk or severity of adverse effects can be increased when Baclofen is combined with Pentolinium.
DB01116
The risk or severity of adverse effects can be increased when Baclofen is combined with Trimethaphan.
DB01119
The risk or severity of adverse effects can be increased when Baclofen is combined with Diazoxide.
DB01136
The risk or severity of adverse effects can be increased when Baclofen is combined with Carvedilol.
DB01158
The risk or severity of adverse effects can be increased when Baclofen is combined with Bretylium.
DB01162
The risk or severity of adverse effects can be increased when Baclofen is combined with Terazosin.
DB01170
The risk or severity of adverse effects can be increased when Baclofen is combined with Guanethidine.
DB01180
The risk or severity of adverse effects can be increased when Baclofen is combined with Rescinnamine.
DB01193
The risk or severity of adverse effects can be increased when Baclofen is combined with Acebutolol.
DB01197
The risk or severity of adverse effects can be increased when Baclofen is combined with Captopril.
DB01203
The risk or severity of adverse effects can be increased when Baclofen is combined with Nadolol.
DB01240
The risk or severity of adverse effects can be increased when Baclofen is combined with Epoprostenol.
DB01244
The risk or severity of adverse effects can be increased when Baclofen is combined with Bepridil.
DB01275
The risk or severity of adverse effects can be increased when Baclofen is combined with Hydralazine.
DB01295
The risk or severity of adverse effects can be increased when Baclofen is combined with Bevantolol.
DB01297
The risk or severity of adverse effects can be increased when Baclofen is combined with Practolol.
DB01324
The risk or severity of adverse effects can be increased when Baclofen is combined with Polythiazide.
DB01340
The risk or severity of adverse effects can be increased when Baclofen is combined with Cilazapril.
DB01347
The risk or severity of adverse effects can be increased when Baclofen is combined with Saprisartan.
DB01348
The risk or severity of adverse effects can be increased when Baclofen is combined with Spirapril.
DB01359
The risk or severity of adverse effects can be increased when Baclofen is combined with Penbutolol.
DB01388
The risk or severity of adverse effects can be increased when Baclofen is combined with Mibefradil.
DB01580
The risk or severity of adverse effects can be increased when Baclofen is combined with Oxprenolol.
DB01626
The risk or severity of adverse effects can be increased when Baclofen is combined with Pargyline.
DB03322
The risk or severity of adverse effects can be increased when Baclofen is combined with Dexpropranolol.
DB04831
The risk or severity of adverse effects can be increased when Baclofen is combined with Tienilic acid.
DB04840
The risk or severity of adverse effects can be increased when Baclofen is combined with Debrisoquine.
DB04846
The risk or severity of adverse effects can be increased when Baclofen is combined with Celiprolol.
DB04861
The risk or severity of adverse effects can be increased when Baclofen is combined with Nebivolol.
DB06268
The risk or severity of adverse effects can be increased when Baclofen is combined with Sitaxentan.
DB06403
The risk or severity of adverse effects can be increased when Baclofen is combined with Ambrisentan.
DB06445
The risk or severity of adverse effects can be increased when Baclofen is combined with Diethylnorspermine.
DB06712
The risk or severity of adverse effects can be increased when Baclofen is combined with Nilvadipine.
DB06762
The risk or severity of adverse effects can be increased when Baclofen is combined with Pinacidil.
DB07767
The risk or severity of adverse effects can be increased when Baclofen is combined with Ferulic acid.
DB08808
The risk or severity of adverse effects can be increased when Baclofen is combined with Bupranolol.
DB08836
The risk or severity of adverse effects can be increased when Baclofen is combined with Temocapril.
DB08931
The risk or severity of adverse effects can be increased when Baclofen is combined with Riociguat.
DB08932
The risk or severity of adverse effects can be increased when Baclofen is combined with Macitentan.
DB08950
The risk or severity of adverse effects can be increased when Baclofen is combined with Indoramin.
DB08952
The risk or severity of adverse effects can be increased when Baclofen is combined with Indenolol.
DB08960
The risk or severity of adverse effects can be increased when Baclofen is combined with Hexamethonium.
DB09026
The risk or severity of adverse effects can be increased when Baclofen is combined with Aliskiren.
DB09206
The risk or severity of adverse effects can be increased when Baclofen is combined with Trimazosin.
DB09220
The risk or severity of adverse effects can be increased when Baclofen is combined with Nicorandil.
DB09235
The risk or severity of adverse effects can be increased when Baclofen is combined with Efonidipine.
DB09238
The risk or severity of adverse effects can be increased when Baclofen is combined with Manidipine.
DB09239
The risk or severity of adverse effects can be increased when Baclofen is combined with Niguldipine.
DB09242
The risk or severity of adverse effects can be increased when Baclofen is combined with Moxonidine.
DB09363
The risk or severity of adverse effects can be increased when Baclofen is combined with Rauwolfia serpentina root.
DB09477
The risk or severity of adverse effects can be increased when Baclofen is combined with Enalaprilat.
DB11362
The risk or severity of adverse effects can be increased when Baclofen is combined with Selexipag.
DB11720
The risk or severity of adverse effects can be increased when Baclofen is combined with Angiotensin 1-7.
DB11738
The risk or severity of adverse effects can be increased when Baclofen is combined with Rilmenidine.
DB11770
The risk or severity of adverse effects can be increased when Baclofen is combined with Talinolol.
DB11783
The risk or severity of adverse effects can be increased when Baclofen is combined with Imidapril.
DB12054
The risk or severity of adverse effects can be increased when Baclofen is combined with BQ-123.
DB12092
The risk or severity of adverse effects can be increased when Baclofen is combined with Naftopidil.
DB12093
The risk or severity of adverse effects can be increased when Baclofen is combined with Tetrahydropalmatine.
DB12212
The risk or severity of adverse effects can be increased when Baclofen is combined with Landiolol.
DB12465
The risk or severity of adverse effects can be increased when Baclofen is combined with Ketanserin.
DB12661
The risk or severity of adverse effects can be increased when Baclofen is combined with Urapidil.
DB12766
The risk or severity of adverse effects can be increased when Baclofen is combined with Cicletanine.
DB12945
The risk or severity of adverse effects can be increased when Baclofen is combined with Dihydralazine.
DB13166
The risk or severity of adverse effects can be increased when Baclofen is combined with Zofenopril.
DB13211
The risk or severity of adverse effects can be increased when Baclofen is combined with Guanoxan.
DB13312
The risk or severity of adverse effects can be increased when Baclofen is combined with Delapril.
DB13374
The risk or severity of adverse effects can be increased when Baclofen is combined with Vincamine.
DB13400
The risk or severity of adverse effects can be increased when Baclofen is combined with Linsidomine.
DB13410
The risk or severity of adverse effects can be increased when Baclofen is combined with Guanoxabenz.
DB13429
The risk or severity of adverse effects can be increased when Baclofen is combined with Tolonidine.
DB13435
The risk or severity of adverse effects can be increased when Baclofen is combined with Endralazine.
DB13443
The risk or severity of adverse effects can be increased when Baclofen is combined with Esatenolol.
DB13452
The risk or severity of adverse effects can be increased when Baclofen is combined with Cadralazine.
DB13508
The risk or severity of adverse effects can be increased when Baclofen is combined with Cloranolol.
DB13532
The risk or severity of adverse effects can be increased when Baclofen is combined with Cyclopenthiazide.
DB13575
The risk or severity of adverse effects can be increased when Baclofen is combined with Bietaserpine.
DB13604
The risk or severity of adverse effects can be increased when Baclofen is combined with Guanazodine.
DB13631
The risk or severity of adverse effects can be increased when Baclofen is combined with Methoserpidine.
DB13757
The risk or severity of adverse effects can be increased when Baclofen is combined with Epanolol.
DB13779
The risk or severity of adverse effects can be increased when Baclofen is combined with Guanoclor.
DB13801
The risk or severity of adverse effects can be increased when Baclofen is combined with Muzolimine.
DB13803
The risk or severity of adverse effects can be increased when Baclofen is combined with Xipamide.
DB13919
The risk or severity of adverse effects can be increased when Baclofen is combined with Candesartan.
DB14068
The risk or severity of adverse effects can be increased when Baclofen is combined with Dexniguldipine.
DB14094
The risk or severity of adverse effects can be increased when Baclofen is combined with Tocopherylquinone.
DB14125
The risk or severity of adverse effects can be increased when Baclofen is combined with Benazeprilat.
DB14207
The risk or severity of adverse effects can be increased when Baclofen is combined with Fosinoprilat.
DB14208
The risk or severity of adverse effects can be increased when Baclofen is combined with Ramiprilat.
DB14213
The risk or severity of adverse effects can be increased when Baclofen is combined with Perindoprilat.
DB14217
The risk or severity of adverse effects can be increased when Baclofen is combined with Quinaprilat.
DB00695
The risk or severity of adverse effects can be increased when Furosemide is combined with Baclofen.
DB09237
The risk or severity of adverse effects can be increased when Baclofen is combined with Levamlodipine.
DB00321
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Amitriptyline.
DB00344
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Protriptyline.
DB00458
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Imipramine.
DB00540
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Nortriptyline.
DB00543
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Amoxapine.
DB00726
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Trimipramine.
DB01142
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Doxepin.
DB01151
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Desipramine.
DB01242
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Clomipramine.
DB04836
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Amineptine.
DB08996
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Dimetacrine.
DB09016
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Butriptyline.
DB09167
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Dosulepin.
DB09289
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Tianeptine.
DB09307
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Oxaprotiline.
DB12930
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Opipramol.
DB13114
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Amitriptylinoxide.
DB13225
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Dibenzepin.
DB13246
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Quinupramine.
DB13384
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Melitracen.
DB13411
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Lofepramine.
DB13496
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Iprindole.
DB13782
The risk or severity of CNS depression and hypotonia can be increased when Baclofen is combined with Imipramine oxide.
DB14507
The risk or severity of hyperkinetic symptoms can be increased when Baclofen is combined with Lithium citrate.
DB14509
The risk or severity of hyperkinetic symptoms can be increased when Baclofen is combined with Lithium carbonate.
DB14506
The risk or severity of hyperkinetic symptoms can be increased when Baclofen is combined with Lithium hydroxide.
DB00182
The risk or severity of hypotension can be increased when Baclofen is combined with Amphetamine.
DB00601
The risk or severity of hypotension can be increased when Baclofen is combined with Linezolid.
DB00614
The risk or severity of hypotension can be increased when Baclofen is combined with Furazolidone.
DB00721
The risk or severity of hypotension can be increased when Baclofen is combined with Procaine.
DB00752
The risk or severity of hypotension can be increased when Baclofen is combined with Tranylcypromine.
DB00780
The risk or severity of hypotension can be increased when Baclofen is combined with Phenelzine.
DB00805
The risk or severity of hypotension can be increased when Baclofen is combined with Minaprine.
DB01037
The risk or severity of hypotension can be increased when Baclofen is combined with Selegiline.
DB01168
The risk or severity of hypotension can be increased when Baclofen is combined with Procarbazine.
DB01171
The risk or severity of hypotension can be increased when Baclofen is combined with Moclobemide.
DB01247
The risk or severity of hypotension can be increased when Baclofen is combined with Isocarboxazid.
DB01367
The risk or severity of hypotension can be increased when Baclofen is combined with Rasagiline.
DB04017
The risk or severity of hypotension can be increased when Baclofen is combined with Clorgiline.
DB04818
The risk or severity of hypotension can be increased when Baclofen is combined with Iproniazid.
DB04820
The risk or severity of hypotension can be increased when Baclofen is combined with Nialamide.
DB06654
The risk or severity of hypotension can be increased when Baclofen is combined with Safinamide.
DB08550
The risk or severity of hypotension can be increased when Baclofen is combined with 7,8-Dichloro-1,2,3,4-tetrahydroisoquinoline.
DB09241
The risk or severity of hypotension can be increased when Baclofen is combined with Methylene blue.
DB09243
The risk or severity of hypotension can be increased when Baclofen is combined with Hydracarbazine.
DB09244
The risk or severity of hypotension can be increased when Baclofen is combined with Pirlindole.
DB09245
The risk or severity of hypotension can be increased when Baclofen is combined with Toloxatone.
DB09246
The risk or severity of hypotension can be increased when Baclofen is combined with Benmoxin.
DB09248
The risk or severity of hypotension can be increased when Baclofen is combined with Mebanazine.
DB09249
The risk or severity of hypotension can be increased when Baclofen is combined with Octamoxin.
DB09250
The risk or severity of hypotension can be increased when Baclofen is combined with Pheniprazine.
DB09251
The risk or severity of hypotension can be increased when Baclofen is combined with Phenoxypropazine.
DB09252
The risk or severity of hypotension can be increased when Baclofen is combined with Pivhydrazine.
DB09253
The risk or severity of hypotension can be increased when Baclofen is combined with Safrazine.
DB09254
The risk or severity of hypotension can be increased when Baclofen is combined with Caroxazone.
DB13875
The risk or severity of hypotension can be increased when Baclofen is combined with Harmaline.
DB13876
The risk or severity of hypotension can be increased when Baclofen is combined with Brofaromine.
DB11823
The risk or severity of adverse effects can be increased when Baclofen is combined with Esketamine.
DB00395
The risk or severity of adverse effects can be increased when Carisoprodol is combined with Baclofen.
DB01459
The risk or severity of respiratory depression can be increased when Bezitramide is combined with Baclofen.
DB09272
The risk or severity of respiratory depression can be increased when Eluxadoline is combined with Baclofen.
DB13454
The risk or severity of respiratory depression can be increased when Nicomorphine is combined with Baclofen.
DB15465
The risk or severity of respiratory depression can be increased when Benzhydrocodone is combined with Baclofen.
DB01235
The therapeutic efficacy of Levodopa can be decreased when used in combination with Baclofen.
DB00030
The therapeutic efficacy of Insulin human can be decreased when used in combination with Baclofen.
DB00046
The therapeutic efficacy of Insulin lispro can be decreased when used in combination with Baclofen.
DB00047
The therapeutic efficacy of Insulin glargine can be decreased when used in combination with Baclofen.
DB00071
The therapeutic efficacy of Insulin pork can be decreased when used in combination with Baclofen.
DB00197
The therapeutic efficacy of Troglitazone can be decreased when used in combination with Baclofen.
DB00222
The therapeutic efficacy of Glimepiride can be decreased when used in combination with Baclofen.
DB00263
The therapeutic efficacy of Sulfisoxazole can be decreased when used in combination with Baclofen.
DB00280
The therapeutic efficacy of Disopyramide can be decreased when used in combination with Baclofen.
DB00284
The therapeutic efficacy of Acarbose can be decreased when used in combination with Baclofen.
DB00331
The therapeutic efficacy of Metformin can be decreased when used in combination with Baclofen.
DB00359
The therapeutic efficacy of Sulfadiazine can be decreased when used in combination with Baclofen.
DB00412
The therapeutic efficacy of Rosiglitazone can be decreased when used in combination with Baclofen.
DB00414
The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Baclofen.
DB00468
The therapeutic efficacy of Quinine can be decreased when used in combination with Baclofen.
DB00491
The therapeutic efficacy of Miglitol can be decreased when used in combination with Baclofen.
DB00672
The therapeutic efficacy of Chlorpropamide can be decreased when used in combination with Baclofen.
DB00731
The therapeutic efficacy of Nateglinide can be decreased when used in combination with Baclofen.
DB00738
The therapeutic efficacy of Pentamidine can be decreased when used in combination with Baclofen.
DB00834
The therapeutic efficacy of Mifepristone can be decreased when used in combination with Baclofen.
DB00839
The therapeutic efficacy of Tolazamide can be decreased when used in combination with Baclofen.
DB00912
The therapeutic efficacy of Repaglinide can be decreased when used in combination with Baclofen.
DB00914
The therapeutic efficacy of Phenformin can be decreased when used in combination with Baclofen.
DB01015
The therapeutic efficacy of Sulfamethoxazole can be decreased when used in combination with Baclofen.
DB01016
The therapeutic efficacy of Glyburide can be decreased when used in combination with Baclofen.
DB01067
The therapeutic efficacy of Glipizide can be decreased when used in combination with Baclofen.
DB01120
The therapeutic efficacy of Gliclazide can be decreased when used in combination with Baclofen.
DB01124
The therapeutic efficacy of Tolbutamide can be decreased when used in combination with Baclofen.
DB01132
The therapeutic efficacy of Pioglitazone can be decreased when used in combination with Baclofen.
DB01200
The therapeutic efficacy of Bromocriptine can be decreased when used in combination with Baclofen.
DB01251
The therapeutic efficacy of Gliquidone can be decreased when used in combination with Baclofen.
DB01252
The therapeutic efficacy of Mitiglinide can be decreased when used in combination with Baclofen.
DB01261
The therapeutic efficacy of Sitagliptin can be decreased when used in combination with Baclofen.
DB01268
The therapeutic efficacy of Sunitinib can be decreased when used in combination with Baclofen.
DB01276
The therapeutic efficacy of Exenatide can be decreased when used in combination with Baclofen.
DB01277
The therapeutic efficacy of Mecasermin can be decreased when used in combination with Baclofen.
DB01278
The therapeutic efficacy of Pramlintide can be decreased when used in combination with Baclofen.
DB01289
The therapeutic efficacy of Glisoxepide can be decreased when used in combination with Baclofen.
DB01306
The therapeutic efficacy of Insulin aspart can be decreased when used in combination with Baclofen.
DB01307
The therapeutic efficacy of Insulin detemir can be decreased when used in combination with Baclofen.
DB01309
The therapeutic efficacy of Insulin glulisine can be decreased when used in combination with Baclofen.
DB01382
The therapeutic efficacy of Glymidine can be decreased when used in combination with Baclofen.
DB01700
The therapeutic efficacy of AICA ribonucleotide can be decreased when used in combination with Baclofen.
DB04830
The therapeutic efficacy of Buformin can be decreased when used in combination with Baclofen.
DB04876
The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Baclofen.
DB04878
The therapeutic efficacy of Voglibose can be decreased when used in combination with Baclofen.
DB05115
The therapeutic efficacy of NN344 can be decreased when used in combination with Baclofen.
DB05819
The therapeutic efficacy of NBI-6024 can be decreased when used in combination with Baclofen.
DB06011
The therapeutic efficacy of AMG-222 can be decreased when used in combination with Baclofen.
DB06127
The therapeutic efficacy of Bisegliptin can be decreased when used in combination with Baclofen.
DB06203
The therapeutic efficacy of Alogliptin can be decreased when used in combination with Baclofen.
DB06292
The therapeutic efficacy of Dapagliflozin can be decreased when used in combination with Baclofen.
DB06335
The therapeutic efficacy of Saxagliptin can be decreased when used in combination with Baclofen.
DB06655
The therapeutic efficacy of Liraglutide can be decreased when used in combination with Baclofen.
DB08382
The therapeutic efficacy of Gosogliptin can be decreased when used in combination with Baclofen.
DB08882
The therapeutic efficacy of Linagliptin can be decreased when used in combination with Baclofen.
DB08907
The therapeutic efficacy of Canagliflozin can be decreased when used in combination with Baclofen.
DB08962
The therapeutic efficacy of Glibornuride can be decreased when used in combination with Baclofen.
DB09022
The therapeutic efficacy of Benfluorex can be decreased when used in combination with Baclofen.
DB09038
The therapeutic efficacy of Empagliflozin can be decreased when used in combination with Baclofen.
DB09043
The therapeutic efficacy of Albiglutide can be decreased when used in combination with Baclofen.
DB09045
The therapeutic efficacy of Dulaglutide can be decreased when used in combination with Baclofen.
DB09198
The therapeutic efficacy of Lobeglitazone can be decreased when used in combination with Baclofen.
DB09199
The therapeutic efficacy of Netoglitazone can be decreased when used in combination with Baclofen.
DB09200
The therapeutic efficacy of Rivoglitazone can be decreased when used in combination with Baclofen.
DB09201
The therapeutic efficacy of Ciglitazone can be decreased when used in combination with Baclofen.
DB09265
The therapeutic efficacy of Lixisenatide can be decreased when used in combination with Baclofen.
DB09456
The therapeutic efficacy of Insulin beef can be decreased when used in combination with Baclofen.
DB09564
The therapeutic efficacy of Insulin degludec can be decreased when used in combination with Baclofen.
DB11567
The therapeutic efficacy of Insulin peglispro can be decreased when used in combination with Baclofen.
DB11568
The therapeutic efficacy of Insulin tregopil can be decreased when used in combination with Baclofen.
DB11698
The therapeutic efficacy of Ipragliflozin can be decreased when used in combination with Baclofen.
DB11723
The therapeutic efficacy of Dutogliptin can be decreased when used in combination with Baclofen.
DB11780
The therapeutic efficacy of Allicin can be decreased when used in combination with Baclofen.
DB11824
The therapeutic efficacy of Tofogliflozin can be decreased when used in combination with Baclofen.
DB11827
The therapeutic efficacy of Ertugliflozin can be decreased when used in combination with Baclofen.
DB11898
The therapeutic efficacy of 2,4-thiazolidinedione can be decreased when used in combination with Baclofen.
DB11950
The therapeutic efficacy of Teneligliptin can be decreased when used in combination with Baclofen.
DB11992
The therapeutic efficacy of Omarigliptin can be decreased when used in combination with Baclofen.
DB12268
The therapeutic efficacy of Carmegliptin can be decreased when used in combination with Baclofen.
DB12412
The therapeutic efficacy of Gemigliptin can be decreased when used in combination with Baclofen.
DB12417
The therapeutic efficacy of Anagliptin can be decreased when used in combination with Baclofen.
DB12625
The therapeutic efficacy of Evogliptin can be decreased when used in combination with Baclofen.
DB12713
The therapeutic efficacy of Sotagliflozin can be decreased when used in combination with Baclofen.
DB12781
The therapeutic efficacy of Balaglitazone can be decreased when used in combination with Baclofen.
DB12935
The therapeutic efficacy of Remogliflozin etabonate can be decreased when used in combination with Baclofen.
DB13406
The therapeutic efficacy of Carbutamide can be decreased when used in combination with Baclofen.
DB13446
The therapeutic efficacy of Guar gum can be decreased when used in combination with Baclofen.
DB13675
The therapeutic efficacy of Metahexamide can be decreased when used in combination with Baclofen.
DB13928
The therapeutic efficacy of Semaglutide can be decreased when used in combination with Baclofen.
DB14027
The therapeutic efficacy of Taspoglutide can be decreased when used in combination with Baclofen.
DB14035
The therapeutic efficacy of Englitazone can be decreased when used in combination with Baclofen.
DB15171
The therapeutic efficacy of Tirzepatide can be decreased when used in combination with Baclofen.
DB15217
The therapeutic efficacy of Gastric inhibitory polypeptide can be decreased when used in combination with Baclofen.
DB00202
The therapeutic efficacy of Succinylcholine can be increased when used in combination with Baclofen.
DB00416
The therapeutic efficacy of Metocurine iodide can be increased when used in combination with Baclofen.
DB00483
The therapeutic efficacy of Gallamine triethiodide can be increased when used in combination with Baclofen.
DB00565
The therapeutic efficacy of Cisatracurium can be increased when used in combination with Baclofen.
DB00728
The therapeutic efficacy of Rocuronium can be increased when used in combination with Baclofen.
DB00732
The therapeutic efficacy of Atracurium besylate can be increased when used in combination with Baclofen.
DB01135
The therapeutic efficacy of Doxacurium can be increased when used in combination with Baclofen.
DB01199
The therapeutic efficacy of Tubocurarine can be increased when used in combination with Baclofen.
DB01226
The therapeutic efficacy of Mivacurium can be increased when used in combination with Baclofen.
DB01245
The therapeutic efficacy of Decamethonium can be increased when used in combination with Baclofen.
DB01336
The therapeutic efficacy of Metocurine can be increased when used in combination with Baclofen.
DB01337
The therapeutic efficacy of Pancuronium can be increased when used in combination with Baclofen.
DB01338
The therapeutic efficacy of Pipecuronium can be increased when used in combination with Baclofen.
DB01339
The therapeutic efficacy of Vecuronium can be increased when used in combination with Baclofen.
DB04834
The therapeutic efficacy of Rapacuronium can be increased when used in combination with Baclofen.
DB11156
The therapeutic efficacy of Pyrantel can be increased when used in combination with Baclofen.
DB12989
The therapeutic efficacy of Neosaxitoxin can be increased when used in combination with Baclofen.
DB13295
The therapeutic efficacy of Atracurium can be increased when used in combination with Baclofen.
DB13584
The therapeutic efficacy of Gallamine can be increased when used in combination with Baclofen.
DB13648
The therapeutic efficacy of Alcuronium can be increased when used in combination with Baclofen.
DB00091
Cyclosporine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00159
Icosapent may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00229
Cefotiam may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00244
Mesalazine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00267
Cefmenoxime may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00274
Cefmetazole may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00282
Pamidronic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00300
Tenofovir disoproxil may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00314
Capreomycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00328
Indomethacin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00369
Cidofovir may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00384
Triamterene may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00430
Cefpiramide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00438
Ceftazidime may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00447
Loracarbef may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00452
Framycetin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00456
Cefalotin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00461
Nabumetone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00465
Ketorolac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00469
Tenoxicam may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00479
Amikacin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00482
Celecoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00493
Cefotaxime may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00500
Tolmetin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00512
Vancomycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00515
Cisplatin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00529
Foscarnet may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00533
Rofecoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00554
Piroxicam may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00563
Methotrexate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00567
Cephalexin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00573
Fenoprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00577
Valaciclovir may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00580
Valdecoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00586
Diclofenac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00605
Sulindac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00626
Bacitracin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00681
Amphotericin B may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00684
Tobramycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00689
Cephaloglycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00712
Flurbiprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00718
Adefovir dipivoxil may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00742
Mannitol may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00749
Etodolac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00784
Mefenamic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00787
Acyclovir may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00788
Naproxen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00795
Sulfasalazine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00798
Gentamicin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00812
Phenylbutazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00814
Meloxicam may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00821
Carprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00833
Cefaclor may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00861
Diflunisal may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00864
Tacrolimus may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00887
Bumetanide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00903
Etacrynic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00923
Ceforanide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00936
Salicylic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00939
Meclofenamic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00945
Acetylsalicylic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00955
Netilmicin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00958
Carboplatin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00991
Oxaprozin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00994
Neomycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01009
Ketoprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01014
Balsalazide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01050
Ibuprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01066
Cefditoren may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01072
Atazanavir may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01082
Streptomycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01111
Colistimethate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01112
Cefuroxime may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01139
Cefapirin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01140
Cefadroxil may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01150
Cefprozil may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01172
Kanamycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01212
Ceftriaxone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01250
Olsalazine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01283
Lumiracoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01326
Cefamandole may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01327
Cefazolin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01328
Cefonicid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01329
Cefoperazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01330
Cefotetan may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01331
Cefoxitin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01332
Ceftizoxime may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01333
Cefradine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01397
Magnesium salicylate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01399
Salsalate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01401
Choline magnesium trisalicylate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01413
Cefepime may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01414
Cefacetrile may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01415
Ceftibuten may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01416
Cefpodoxime may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01419
Antrafenine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01421
Paromomycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01424
Aminophenazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01435
Antipyrine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01600
Tiaprofenic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01601
Lopinavir may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01628
Etoricoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB02247
Hydrolyzed Cephalothin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB03450
Cephalothin Group may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB03585
Oxyphenbutazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB03615
Ribostamycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04263
Geneticin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04570
Latamoxef may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04626
Apramycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04729
Gentamicin C1a may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04743
Nimesulide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04808
Neamine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04812
Benoxaprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04817
Metamizole may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04828
Zomepirac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB04918
Ceftobiprole may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB05095
Cimicoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB06590
Ceftaroline fosamil may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB06696
Arbekacin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB06725
Lornoxicam may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB06736
Aceclofenac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB06737
Zaltoprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB07402
Azapropazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08437
Puromycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08439
Parecoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08797
Salicylamide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08940
Kebuzone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08942
Isoxicam may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08951
Indoprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08955
Ibuproxam may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08976
Floctafenine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08981
Fenbufen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08984
Etofenamate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB08991
Epirizole may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09008
Cefaloridine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09062
Cefminox may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09084
Benzydamine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09213
Dexibuprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09214
Dexketoprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09215
Droxicam may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09216
Tolfenamic acid may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09217
Firocoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09218
Clonixin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09285
Morniflumate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09288
Propacetamol may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09295
Talniflumate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09299
Tenofovir alafenamide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB11367
Cefroxadine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB11455
Robenacoxib may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB11466
Tepoxalin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB11512
Dihydrostreptomycin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB11518
Flunixin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB11520
Hygromycin B may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB11935
Flomoxef may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB12151
Brincidofovir may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB12445
Nitroaspirin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB12545
Indobufen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB12604
Sisomicin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB12615
Plazomicin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13001
Tinoridine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13167
Alclofenac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13217
Fentiazac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13232
Suxibuzone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13266
Cefatrizine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13286
Bumadizone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13314
Alminoprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13371
Difenpiramide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13407
Nifenazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13432
Lonazolac may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13461
Cefcapene may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13470
Cefodizime may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13481
Tenidap may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13499
Cefsulodin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13504
Cefetamet may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13524
Propyphenazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13527
Proglumetacin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13538
Guacetisal may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13540
Isepamicin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13544
Ethenzamide may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13612
Carbaspirin calcium may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13629
Mofebutazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13638
Cefbuperazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13649
Proquazone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13657
Benorilate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13667
Cefozopran may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13682
Cefpirome may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13722
Pirprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13778
Cefazedone may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13783
Acemetacin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13821
Ceftezole may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13860
Imidazole salicylate may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB13868
Adefovir may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB14059
SC-236 may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB14060
NS-398 may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB14126
Tenofovir may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB14713
Inotersen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01438
Phenazopyridine may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB15066
Givosiran may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB09212
Loxoprofen may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB00803
Colistin may decrease the excretion rate of Baclofen which could result in a higher serum level.
DB01356
Baclofen may decrease the excretion rate of Lithium cation which could result in a higher serum level.
DB00402
The risk or severity of CNS depression can be increased when Baclofen is combined with Eszopiclone.
DB00575
The risk or severity of sedation can be increased when Clonidine is combined with Baclofen.
DB00924
The risk or severity of CNS depression can be increased when Baclofen is combined with Cyclobenzaprine.
DB01233
The risk or severity of sedation can be increased when Baclofen is combined with Metoclopramide.
DB11732
The risk or severity of adverse effects can be increased when Baclofen is combined with Lasmiditan.
DB00193
The risk or severity of CNS depression can be increased when Baclofen is combined with Tramadol.
DB00246
The risk or severity of adverse effects can be increased when Baclofen is combined with Ziprasidone.
DB00502
The risk or severity of CNS depression can be increased when Baclofen is combined with Haloperidol.
DB00472
Baclofen may increase the central nervous system depressant (CNS depressant) activities of Fluoxetine.
DB14881
The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Baclofen is combined with Oliceridine.
序列
实验性质
Water Solubility
slightly soluble
FDA label
Melting Point
207
MSDS
Boiling Point
Decomposes
MSDS
logP
1.3
http://www.hmdb.ca/metabolites/HMDB0014327
caco2 Permeability
0.9
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186984/
pKa
9.62 + 0.1 (amino group) and 3.87 + 0.1 (carboxyl group)
http://www.labriva.com/monographies/02242151eng.pdf
外部标识符
resource:Drugs Product Database (DPD)
identifier:2104
resource:ChEBI
identifier:2972
resource:PubChem Compound
identifier:2284
resource:PubChem Substance
identifier:46508181
resource:KEGG Drug
identifier:D00241
resource:ChemSpider
identifier:2197
resource:BindingDB
identifier:24182
resource:PharmGKB
identifier:PA448533
resource:Therapeutic Targets Database
identifier:DAP000257
resource:IUPHAR
identifier:1084
resource:Guide to Pharmacology
identifier:1084
resource:Wikipedia
identifier:Baclofen
resource:ChEMBL
identifier:CHEMBL701
resource:RxCUI
identifier:1292
外部链接
RxList
http://www.rxlist.com/cgi/generic/baclofen.htm
Drugs.com
http://www.drugs.com/baclofen.html
路径
目标
id:BE0000217
name:Gamma-aminobutyric acid type B receptor subunit 1
organism:Humans
action:agonist
Bowery NG: GABAB receptor pharmacology. Annu Rev Pharmacol Toxicol. 1993;33:109-47.
Garcia-Gil L, de Miguel R, Romero J, Perez A, Ramos JA, Fernandez-Ruiz JJ: Perinatal delta9-tetrahydrocannabinol exposure augmented the magnitude of motor inhibition caused by GABA(B), but not GABA(A), receptor agonists in adult rats. Neurotoxicol Teratol. 1999 May-Jun;21(3):277-83.
Lehmann A: GABAB receptors as drug targets to treat gastroesophageal reflux disease. Pharmacol Ther. 2009 Jun;122(3):239-45. doi: 10.1016/j.pharmthera.2009.02.008. Epub 2009 Mar 19.
Motalli R, Louvel J, Tancredi V, Kurcewicz I, Wan-Chow-Wah D, Pumain R, Avoli M: GABA(B) receptor activation promotes seizure activity in the juvenile rat hippocampus. J Neurophysiol. 1999 Aug;82(2):638-47.
Mott DD, Li Q, Okazaki MM, Turner DA, Lewis DV: GABAB-Receptor-mediated currents in interneurons of the dentate-hilus border. J Neurophysiol. 1999 Sep;82(3):1438-50.
Ogasawara T, Itoh Y, Tamura M, Mushiroi T, Ukai Y, Kise M, Kimura K: Involvement of cholinergic and GABAergic systems in the reversal of memory disruption by NS-105, a cognition enhancer. Pharmacol Biochem Behav. 1999 Sep;64(1):41-52.
Pittman QJ: The action is at the terminal. J Physiol. 1999 Nov 1;520 Pt 3:629.
Stringer JL, Lorenzo N: The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation. Epilepsy Res. 1999 Feb;33(2-3):169-76.
Fu Z, Yang H, Xiao Y, Zhao G, Huang H: The gamma-aminobutyric acid type B (GABAB) receptor agonist baclofen inhibits morphine sensitization by decreasing the dopamine level in rat nucleus accumbens. Behav Brain Funct. 2012 Jul 10;8:20. doi: 10.1186/1744-9081-8-20.
Chen K, Li HZ, Ye N, Zhang J, Wang JJ: Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro. Brain Res Bull. 2005 Oct 30;67(4):310-8. doi: 10.1016/j.brainresbull.2005.07.004.
known-action:unknown
name:Gamma-aminobutyric acid type B receptor subunit 1
general-function:G-protein coupled gaba receptor activity
specific-function:Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Calcium is required for high affinity binding to GABA. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception. Activated by (-)-baclofen, cgp27492 and blocked by phaclofen.Isoform 1E may regulate the formation of functional GABBR1/GABBR2 heterodimers by competing for GABBR2 binding. This could explain the observation that certain small molecule ligands exhibit differential affinity for central versus peripheral sites.
gene-name:GABBR1
locus:6p21.31
cellular-location:Cell membrane
transmembrane-regions:592-612 632-652 668-688 711-731 769-789 805-825 834-854
signal-regions:1-14
theoretical-pi:8.3
molecular-weight:108319.4
chromosome-location:6
organism:Humans
external-identifiers:HUGO Gene Nomenclature Committee (HGNC)HGNC:4070GenAtlasGABBR1GenBank Gene DatabaseAJ225028GenBank Protein Database3892594IUPHAR240Guide to Pharmacology240UniProtKBQ9UBS5UniProt AccessionGABR1_HUMAN
synonyms:GABA-B receptor 1GPRC3A
amino-acid-sequence:>lcl|BSEQ0000433|Gamma-aminobutyric acid type B receptor subunit 1 MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY K
gene-sequence:>lcl|BSEQ0010206|Gamma-aminobutyric acid type B receptor subunit 1 (GABBR1) ATGTTGCTGCTGCTGCTACTGGCGCCACTCTTCCTCCGCCCCCCGGGCGCGGGCGGGGCG CAGACCCCCAACGCCACCTCAGAAGGTTGCCAGATCATACACCCGCCCTGGGAAGGGGGC ATCAGGTACCGGGGCCTGACTCGGGACCAGGTGAAGGCTATCAACTTCCTGCCAGTGGAC TATGAGATTGAGTATGTGTGCCGGGGGGAGCGCGAGGTGGTGGGGCCCAAGGTCCGCAAG TGCCTGGCCAACGGCTCCTGGACAGATATGGACACACCCAGCCGCTGTGTCCGAATCTGC TCCAAGTCTTATTTGACCCTGGAAAATGGGAAGGTTTTCCTGACGGGTGGGGACCTCCCA GCTCTGGACGGAGCCCGGGTGGATTTCCGGTGTGACCCCGACTTCCATCTGGTGGGCAGC TCCCGGAGCATCTGTAGTCAGGGCCAGTGGAGCACCCCCAAGCCCCACTGCCAGGTGAAT CGAACGCCACACTCAGAACGGCGCGCAGTGTACATCGGGGCACTGTTTCCCATGAGCGGG GGCTGGCCAGGGGGCCAGGCCTGCCAGCCCGCGGTGGAGATGGCGCTGGAGGACGTGAAT AGCCGCAGGGACATCCTGCCGGACTATGAGCTCAAGCTCATCCACCACGACAGCAAGTGT GATCCAGGCCAAGCCACCAAGTACCTATATGAGCTGCTCTACAACGACCCTATCAAGATC ATCCTTATGCCTGGCTGCAGCTCTGTCTCCACGCTGGTGGCTGAGGCTGCTAGGATGTGG AACCTCATTGTGCTTTCCTATGGCTCCAGCTCACCAGCCCTGTCAAACCGGCAGCGTTTC CCCACTTTCTTCCGAACGCACCCATCAGCCACACTCCACAACCCTACCCGCGTGAAACTC TTTGAAAAGTGGGGCTGGAAGAAGATTGCTACCATCCAGCAGACCACTGAGGTCTTCACT TCGACTCTGGACGACCTGGAGGAACGAGTGAAGGAGGCTGGAATTGAGATTACTTTCCGC CAGAGTTTCTTCTCAGATCCAGCTGTGCCCGTCAAAAACCTGAAGCGCCAGGATGCCCGA ATCATCGTGGGACTTTTCTATGAGACTGAAGCCCGGAAAGTTTTTTGTGAGGTGTACAAG GAGCGTCTCTTTGGGAAGAAGTACGTCTGGTTCCTCATTGGGTGGTATGCTGACAATTGG TTCAAGATCTACGACCCTTCTATCAACTGCACAGTGGATGAGATGACTGAGGCGGTGGAG GGCCACATCACAACTGAGATTGTCATGCTGAATCCTGCCAATACCCGCAGCATTTCCAAC ATGACATCCCAGGAATTTGTGGAGAAACTAACCAAGCGACTGAAAAGACACCCTGAGGAG ACAGGAGGCTTCCAGGAGGCACCGCTGGCCTATGATGCCATCTGGGCCTTGGCACTGGCC CTGAACAAGACATCTGGAGGAGGCGGCCGTTCTGGTGTGCGCCTGGAGGACTTCAACTAC AACAACCAGACCATTACCGACCAAATCTACCGGGCAATGAACTCTTCGTCCTTTGAGGGT GTCTCTGGCCATGTGGTGTTTGATGCCAGCGGCTCTCGGATGGCATGGACGCTTATCGAG CAGCTTCAGGGTGGCAGCTACAAGAAGATTGGCTACTATGACAGCACCAAGGATGATCTT TCCTGGTCCAAAACAGATAAATGGATTGGAGGGTCCCCCCCAGCTGACCAGACCCTGGTC ATCAAGACATTCCGCTTCCTGTCACAGAAACTCTTTATCTCCGTCTCAGTTCTCTCCAGC CTGGGCATTGTCCTAGCTGTTGTCTGTCTGTCCTTTAACATCTACAACTCACATGTCCGT TATATCCAGAACTCACAGCCCAACCTGAACAACCTGACTGCTGTGGGCTGCTCACTGGCT TTAGCTGCTGTCTTCCCCCTGGGGCTCGATGGTTACCACATTGGGAGGAACCAGTTTCCT TTCGTCTGCCAGGCCCGCCTCTGGCTCCTGGGCCTGGGCTTTAGTCTGGGCTACGGTTCC ATGTTCACCAAGATTTGGTGGGTCCACACGGTCTTCACAAAGAAGGAAGAAAAGAAGGAG TGGAGGAAGACTCTGGAACCCTGGAAGCTGTATGCCACAGTGGGCCTGCTGGTGGGCATG GATGTCCTCACTCTCGCCATCTGGCAGATCGTGGACCCTCTGCACCGGACCATTGAGACA TTTGCCAAGGAGGAACCTAAGGAAGATATTGACGTCTCTATTCTGCCCCAGCTGGAGCAT TGCAGCTCCAGGAAGATGAATACATGGCTTGGCATTTTCTATGGTTACAAGGGGCTGCTG CTGCTGCTGGGAATCTTCCTTGCTTATGAGACCAAGAGTGTGTCCACTGAGAAGATCAAT GATCACCGGGCTGTGGGCATGGCTATCTACAATGTGGCAGTCCTGTGCCTCATCACTGCT CCTGTCACCATGATTCTGTCCAGCCAGCAGGATGCAGCCTTTGCCTTTGCCTCTCTTGCC ATAGTTTTCTCCTCCTATATCACTCTTGTTGTGCTCTTTGTGCCCAAGATGCGCAGGCTG ATCACCCGAGGGGAATGGCAGTCGGAGGCGCAGGACACCATGAAGACAGGGTCATCGACC AACAACAACGAGGAGGAGAAGTCCCGGCTGTTGGAGAAGGAGAACCGTGAACTGGAAAAG ATCATTGCTGAGAAAGAGGAGCGTGTCTCTGAACTGCGCCATCAACTCCAGTCTCGGCAG CAGCTCCGCTCCCGGCGCCACCCACCGACACCCCCAGAACCCTCTGGGGGCCTGCCCAGG GGACCCCCTGAGCCCCCCGACCGGCTTAGCTGTGATGGGAGTCGAGTGCATTTGCTTTAT AAGTGA
pfams:PF000037tm_3PF01094ANF_receptorPF00084Sushi
go-classifiers:componentcell junctioncomponentcytoplasmcomponentdendritecomponentextracellular regioncomponentG-protein coupled receptor heterodimeric complexcomponentintegral component of plasma membranecomponentplasma membranecomponentpostsynaptic membranecomponentpresynaptic membranefunctionG-protein coupled GABA receptor activityprocessadenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayprocessgamma-aminobutyric acid signaling pathwayprocessnegative regulation of adenylate cyclase activityprocesssynaptic transmission
id:BE0002340
name:Gamma-aminobutyric acid type B receptor subunit 2
organism:Humans
action:agonist
Braun M, Wendt A, Buschard K, Salehi A, Sewing S, Gromada J, Rorsman P: GABAB receptor activation inhibits exocytosis in rat pancreatic beta-cells by G-protein-dependent activation of calcineurin. J Physiol. 2004 Sep 1;559(Pt 2):397-409. Epub 2004 Jul 2.
Bowery NG: GABAB receptor pharmacology. Annu Rev Pharmacol Toxicol. 1993;33:109-47.
Filippov AK, Couve A, Pangalos MN, Walsh FS, Brown DA, Moss SJ: Heteromeric assembly of GABA(B)R1 and GABA(B)R2 receptor subunits inhibits Ca(2+) current in sympathetic neurons. J Neurosci. 2000 Apr 15;20(8):2867-74.
Lehmann A: GABAB receptors as drug targets to treat gastroesophageal reflux disease. Pharmacol Ther. 2009 Jun;122(3):239-45. doi: 10.1016/j.pharmthera.2009.02.008. Epub 2009 Mar 19.
Martin SC, Russek SJ, Farb DH: Molecular identification of the human GABABR2: cell surface expression and coupling to adenylyl cyclase in the absence of GABABR1. Mol Cell Neurosci. 1999 Mar;13(3):180-91.
Pittman QJ: The action is at the terminal. J Physiol. 1999 Nov 1;520 Pt 3:629.
Fu Z, Yang H, Xiao Y, Zhao G, Huang H: The gamma-aminobutyric acid type B (GABAB) receptor agonist baclofen inhibits morphine sensitization by decreasing the dopamine level in rat nucleus accumbens. Behav Brain Funct. 2012 Jul 10;8:20. doi: 10.1186/1744-9081-8-20.
Chen K, Li HZ, Ye N, Zhang J, Wang JJ: Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro. Brain Res Bull. 2005 Oct 30;67(4):310-8. doi: 10.1016/j.brainresbull.2005.07.004.
known-action:yes
name:Gamma-aminobutyric acid type B receptor subunit 2
general-function:G-protein coupled gaba receptor activity
specific-function:Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception.
gene-name:GABBR2
locus:9q22.1-q22.3
cellular-location:Cell membrane
transmembrane-regions:484-504 523-543 552-572 598-618 655-675 692-712 721-741
signal-regions:1-41
theoretical-pi:8.83
molecular-weight:105820.52
chromosome-location:9
organism:Humans
external-identifiers:HUGO Gene Nomenclature Committee (HGNC)HGNC:4507GenAtlasGABBR2GenBank Gene DatabaseAJ012188GenBank Protein Database3776098IUPHAR241UniProtKBO75899UniProt AccessionGABR2_HUMAN
synonyms:G-protein coupled receptor 51GABA-B receptor 2GPR51GPRC3BHG20
amino-acid-sequence:>lcl|BSEQ0004595|Gamma-aminobutyric acid type B receptor subunit 2 MASPRSSGQPGPPPPPPPPPARLLLLLLLPLLLPLAPGAWGWARGAPRPPPSSPPLSIMG LMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDA IKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDN AVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSV KKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSS RCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYD GIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFRNG ERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLP LYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLD GSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVI VGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIV YAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQ FCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSV NQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILNL GNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILH HAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL
gene-sequence:>lcl|BSEQ0016760|Gamma-aminobutyric acid type B receptor subunit 2 (GABBR2) ATGGCTTCCCCGCGGAGCTCCGGGCAGCCCGGGCCGCCGCCGCCGCCGCCACCGCCGCCC GCGCGCCTGCTACTGCTACTGCTGCTGCCGCTGCTGCTGCCTCTGGCGCCCGGGGCCTGG GGCTGGGCGCGGGGCGCCCCCCGGCCGCCGCCCAGCAGCCCGCCGCTCTCCATCATGGGC CTCATGCCGCTCACCAAGGAGGTGGCCAAGGGCAGCATCGGGCGCGGTGTGCTCCCCGCC GTGGAACTGGCCATCGAGCAGATCCGCAACGAGTCACTCCTGCGCCCCTACTTCCTCGAC CTGCGGCTCTATGACACGGAGTGCGACAACGCAAAAGGGTTGAAAGCCTTCTACGATGCA ATAAAATACGGGCCTAACCACTTGATGGTGTTTGGAGGCGTCTGTCCATCCGTCACATCC ATCATTGCAGAGTCCCTCCAAGGCTGGAATCTGGTGCAGCTTTCTTTTGCTGCAACCACG CCTGTTCTAGCCGATAAGAAAAAATACCCTTATTTCTTTCGGACCGTCCCATCAGACAAT GCGGTGAATCCAGCCATTCTGAAGTTGCTCAAGCACTACCAGTGGAAGCGCGTGGGCACG CTGACGCAAGACGTTCAGAGGTTCTCTGAGGTGCGGAATGACCTGACTGGAGTTCTGTAT GGCGAGGACATTGAGATTTCAGACACCGAGAGCTTCTCCAACGATCCCTGTACCAGTGTC AAAAAGCTGAAGGGGAATGATGTGCGGATCATCCTTGGCCAGTTTGACCAGAATATGGCA GCAAAAGTGTTCTGTTGTGCATACGAGGAGAACATGTATGGTAGTAAATATCAGTGGATC ATTCCGGGCTGGTACGAGCCTTCTTGGTGGGAGCAGGTGCACACGGAAGCCAACTCATCC CGCTGCCTCCGGAAGAATCTGCTTGCTGCCATGGAGGGCTACATTGGCGTGGATTTCGAG CCCCTGAGCTCCAAGCAGATCAAGACCATCTCAGGAAAGACTCCACAGCAGTATGAGAGA GAGTACAACAACAAGCGGTCAGGCGTGGGGCCCAGCAAGTTCCACGGGTACGCCTACGAT GGCATCTGGGTCATCGCCAAGACACTGCAGAGGGCCATGGAGACACTGCATGCCAGCAGC CGGCACCAGCGGATCCAGGACTTCAACTACACGGACCACACGCTGGGCAGGATCATCCTC AATGCCATGAACGAGACCAACTTCTTCGGGGTCACGGGTCAAGTTGTATTCCGGAATGGG GAGAGAATGGGGACCATTAAATTTACTCAATTTCAAGACAGCAGGGAGGTGAAGGTGGGA GAGTACAACGCTGTGGCCGACACACTGGAGATCATCAATGACACCATCAGGTTCCAAGGA TCCGAACCACCAAAAGACAAGACCATCATCCTGGAGCAGCTGCGGAAGATCTCCCTACCT CTCTACAGCATCCTCTCTGCCCTCACCATCCTCGGGATGATCATGGCCAGTGCTTTTCTC TTCTTCAACATCAAGAACCGGAATCAGAAGCTCATAAAGATGTCGAGTCCATACATGAAC AACCTTATCATCCTTGGAGGGATGCTCTCCTATGCTTCCATATTTCTCTTTGGCCTTGAT GGATCCTTTGTCTCTGAAAAGACCTTTGAAACACTTTGCACCGTCAGGACCTGGATTCTC ACCGTGGGCTACACGACCGCTTTTGGGGCCATGTTTGCAAAGACCTGGAGAGTCCACGCC ATCTTCAAAAATGTGAAAATGAAGAAGAAGATCATCAAGGACCAGAAACTGCTTGTGATC GTGGGGGGCATGCTGCTGATCGACCTGTGTATCCTGATCTGCTGGCAGGCTGTGGACCCC CTGCGAAGGACAGTGGAGAAGTACAGCATGGAGCCGGACCCAGCAGGACGGGATATCTCC ATCCGCCCTCTCCTGGAGCACTGTGAGAACACCCATATGACCATCTGGCTTGGCATCGTC TATGCCTACAAGGGACTTCTCATGTTGTTCGGTTGTTTCTTAGCTTGGGAGACCCGCAAC GTCAGCATCCCCGCACTCAACGACAGCAAGTACATCGGGATGAGTGTCTACAACGTGGGG ATCATGTGCATCATCGGGGCCGCTGTCTCCTTCCTGACCCGGGACCAGCCCAATGTGCAG TTCTGCATCGTGGCTCTGGTCATCATCTTCTGCAGCACCATCACCCTCTGCCTGGTATTC GTGCCGAAGCTCATCACCCTGAGAACAAACCCAGATGCAGCAACGCAGAACAGGCGATTC CAGTTCACTCAGAATCAGAAGAAAGAAGATTCTAAAACGTCCACCTCGGTCACCAGTGTG AACCAAGCCAGCACATCCCGCCTGGAGGGCCTACAGTCAGAAAACCATCGCCTGCGAATG AAGATCACAGAGCTGGATAAAGACTTGGAAGAGGTCACCATGCAGCTGCAGGACACACCA GAAAAGACCACCTACATTAAACAGAACCACTACCAAGAGCTCAATGACATCCTCAACCTG GGAAACTTCACTGAGAGCACAGATGGAGGAAAGGCCATTTTAAAAAATCACCTCGATCAA AATCCCCAGCTACAGTGGAACACAACAGAGCCCTCTCGAACATGCAAAGATCCTATAGAA GATATAAACTCTCCAGAACACATCCAGCGTCGGCTGTCCCTCCAGCTCCCCATCCTCCAC CACGCCTACCTCCCATCCATCGGAGGCGTGGACGCCAGCTGTGTCAGCCCCTGCGTCAGC CCCACCGCCAGCCCCCGCCACAGACATGTGCCACCCTCCTTCCGAGTCATGGTCTCGGGC CTGTAA
pfams:PF000037tm_3PF01094ANF_receptor
go-classifiers:componentcell junctioncomponentcytoplasmcomponentG-protein coupled receptor heterodimeric complexcomponentintegral component of plasma membranecomponentneuron projectioncomponentplasma membranecomponentpostsynaptic membranefunctionG-protein coupled GABA receptor activityprocessG-protein coupled receptor signaling pathwayprocessgamma-aminobutyric acid signaling pathwayprocessnegative regulation of adenylate cyclase activityprocesssynaptic transmission
载体
运输工具
药物反应
reactions:1
left-element--drugbank-id:DB00181
left-element--name:Baclofen
right-element--drugbank-id:DBMET02215
right-element--name:3-(p-chlorophenyl)-4-hydroxybutyric acid
效应
不良反应