ID

DB08958||

名称

Hexetidine

描述

A bactericidal and fungicidal antiseptic. It is used as a 0.1% mouthwash for local infections and oral hygiene.

cas号

141-94-6

唯一标识码

852A84Y8LS

状态

solid

组

approved,investigational,

指示

药效学

作用机制

毒性

代谢

吸收

半衰期

分类

description:This compound belongs to the class of organic compounds known as diazinanes. These are organic compounds containing diazinane, a six-membered saturated heterocycle containing four carbon atoms and two nitrogen atoms.
direct-parent:Diazinanes
kingdom:Organic compounds
superclass:Organoheterocyclic compounds
class:Diazinanes
subclass:
alternative-parent:Aminals
alternative-parent:Azacyclic compounds
alternative-parent:Hydrocarbon derivatives
alternative-parent:Monoalkylamines
alternative-parent:Organopnictogen compounds
substituent:1,3-diazinane
substituent:Aliphatic heteromonocyclic compound
substituent:Aminal
substituent:Amine
substituent:Azacycle
substituent:Hydrocarbon derivative
substituent:Organic nitrogen compound
substituent:Organonitrogen compound
substituent:Organopnictogen compound
substituent:Primary aliphatic amine
substituent:Primary amine

消除途径

种类

Alimentary Tract and Metabolism

Anti-Infective Agents
D000890
Anti-Infective Agents, Local
D000891
Antifungal Agents
D000935
Antiinfectives and Antiseptics for Local Oral Treatment

Genito Urinary System and Sex Hormones

Gynecological Antiinfectives and Antiseptics

Pyrimidines
D011743
Stomatological Preparations

盐类

蛋白质结合

清除

同义词

language:english; code:dcit; name;Esetidina
language:spanish; code:inn; name;Hexetidina
language:english; code:inn; name;Hexetidine
language:french; code:dcf; name;Hexétidine
language:latin; code:inn; name;Hexetidinum

国际品牌

Actigrip GolaJohnson & JohnsonBactidolJohnson & JohnsonBeloseptBelupoCollu-HextrilJohnson & JohnsonHexoralJohnson & JohnsonHextrilBristol-Myers SquibbIsozid-HGebroOraldeneMcNeilOraldineJohnson & JohnsonSteri/SolJohnson & JohnsonStomatidinBosnalijekStopanginIvaxVagi-HexDrossapharm

配送量

产品

name:Steri/sol Liquid
labeller:Johnson & Johnson
ndc-id:
ndc-product-code:
dpd-id:01946900
ema-product-code:
ema-ma-number:
started-marketing-on:1992-12-31
ended-marketing-on:2013-07-31
dosage-form:Liquid
strength:
route:Buccal
fda-application-number:
generic:false
over-the-counter:true
approved:true
country:Canada
source:DPD

混合物

name:Steri/sol Liquid
ingredients:Hexetidine

包装者

生产者

价格

受影响的生物体

剂量

form:Mouthwash
route:Oral
strength:100 MG/100ML
form:Mouthwash
route:Oral
strength:15 MG/ML
form:Spray
route:Oral
strength:0.2 G/100ML
form:Mouthwash
route:Oral
strength:0.1 %w/v
form:Solution
route:Buccal; Oral
strength:0.1 g
form:Rinse
route:Oral
strength:100 ml
form:Rinse
route:Oral
strength:200 ml
form:Rinse
route:Oral
strength:0.1 %
form:Solution
route:Topical
strength:314 mg
form:Solution
route:Topical
strength:281 mg
form:Solution
route:Buccal; Oropharyngeal
strength:0.1 g
form:Liquid
route:Buccal
strength:
form:Suppository
route:Vaginal
strength:10 mg

atc代码

Other antiinfectives and antiseptics
ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
GENITO URINARY SYSTEM AND SEX HORMONES
Antiinfectives and antiseptics for local oral treatment
STOMATOLOGICAL PREPARATIONS
STOMATOLOGICAL PREPARATIONS
ALIMENTARY TRACT AND METABOLISM

fda标签

化学品安全技术说明书

//s3-us-west-2.amazonaws.com/drugbank/msds/DB08958.pdf?1401311505

专利

食物相互作用

药物相互作用

DB00266
The therapeutic efficacy of Dicoumarol can be increased when used in combination with Hexetidine.
DB00498
The therapeutic efficacy of Phenindione can be increased when used in combination with Hexetidine.
DB00682
The therapeutic efficacy of Warfarin can be increased when used in combination with Hexetidine.
DB00946
The therapeutic efficacy of Phenprocoumon can be increased when used in combination with Hexetidine.
DB01418
The therapeutic efficacy of Acenocoumarol can be increased when used in combination with Hexetidine.
DB03410
The therapeutic efficacy of 4-hydroxycoumarin can be increased when used in combination with Hexetidine.
DB04665
The therapeutic efficacy of Coumarin can be increased when used in combination with Hexetidine.
DB08496
The therapeutic efficacy of (R)-warfarin can be increased when used in combination with Hexetidine.
DB08794
The therapeutic efficacy of Ethyl biscoumacetate can be increased when used in combination with Hexetidine.
DB13136
The therapeutic efficacy of Fluindione can be increased when used in combination with Hexetidine.
DB13275
The therapeutic efficacy of Clorindione can be increased when used in combination with Hexetidine.
DB13347
The therapeutic efficacy of Diphenadione can be increased when used in combination with Hexetidine.
DB13451
The therapeutic efficacy of Tioclomarol can be increased when used in combination with Hexetidine.
DB14055
The therapeutic efficacy of (S)-Warfarin can be increased when used in combination with Hexetidine.

序列

实验性质

外部标识符

resource：Drugs Product Database (DPD)
identifier：7094
resource：ChEBI
identifier：94339
resource：PubChem Compound
identifier：3607
resource：PubChem Substance
identifier：310264923
resource：KEGG Drug
identifier：D07068
resource：ChemSpider
identifier：3481
resource：Wikipedia
identifier：Hexetidine
resource：ChEMBL
identifier：CHEMBL144673
resource：RxCUI
identifier：5301

外部链接

Drugs.com
http://www.drugs.com/international/Hexetidine.html

路径

目标

酶

载体

运输工具

药物反应

效应

不良反应