ID

DB08967||

名称

Dimetotiazine

描述

Dimetotiazine has considerable antiemetic & serotonin antagonistic action used mainly in allergic skin conditions.

cas号

7456-24-8

唯一标识码

1FTA475ZDB

状态

solid

组

approved,

指示

药效学

作用机制

毒性

代谢

吸收

半衰期

分类

description:This compound belongs to the class of organic compounds known as phenothiazines. These are polycyclic aromatic compounds containing a phenothiazine moiety, which is a linear tricyclic system that consists of a two benzene rings joined by a para-thiazine ring.
direct-parent:Phenothiazines
kingdom:Organic compounds
superclass:Organoheterocyclic compounds
class:Benzothiazines
subclass:Phenothiazines
alternative-parent:1,4-thiazines
alternative-parent:Alkyldiarylamines
alternative-parent:Aminosulfonyl compounds
alternative-parent:Azacyclic compounds
alternative-parent:Benzenoids
alternative-parent:Diarylthioethers
alternative-parent:Hydrocarbon derivatives
alternative-parent:Organic oxides
alternative-parent:Organopnictogen compounds
alternative-parent:Organosulfonamides
alternative-parent:Trialkylamines
substituent:Alkyldiarylamine
substituent:Amine
substituent:Aminosulfonyl compound
substituent:Aromatic heteropolycyclic compound
substituent:Aryl thioether
substituent:Azacycle
substituent:Benzenoid
substituent:Diarylthioether
substituent:Hydrocarbon derivative
substituent:Organic nitrogen compound
substituent:Organic oxide
substituent:Organic oxygen compound
substituent:Organic sulfonic acid or derivatives
substituent:Organonitrogen compound
substituent:Organopnictogen compound
substituent:Organosulfonic acid amide
substituent:Organosulfonic acid or derivatives
substituent:Organosulfur compound
substituent:Para-thiazine
substituent:Phenothiazine
substituent:Sulfonyl
substituent:Tertiary aliphatic amine
substituent:Tertiary aliphatic/aromatic amine
substituent:Tertiary amine
substituent:Thioether

消除途径

种类

Analgesics
D000700
Antimigraine Preparations

Heterocyclic Compounds, Fused-Ring
D000072471
Histamine Agents
D018494
Histamine Antagonists
D006633
Histamine H1 Antagonists
D006634
Nervous System
D009420
Neurotransmitter Agents
D018377
Sulfur Compounds
D013457

盐类

DBSALT002448Fonazine mesylateB28V86NGNK13115-40-7JGKVKXPDDVRUKC-UHFFFAOYSA-N487.656487.126933123

蛋白质结合

清除

同义词

国际品牌

配送量

产品

混合物

包装者

生产者

价格

受影响的生物体

剂量

atc代码

Other antimigraine preparations
ANTIMIGRAINE PREPARATIONS
ANALGESICS
NERVOUS SYSTEM

fda标签

化学品安全技术说明书

专利

食物相互作用

药物相互作用

DB00895
Dimetotiazine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
DB06698
The therapeutic efficacy of Betahistine can be decreased when used in combination with Dimetotiazine.
DB00070
The therapeutic efficacy of Hyaluronidase (ovine) can be decreased when used in combination with Dimetotiazine.
DB06205
The therapeutic efficacy of Hyaluronidase (human recombinant) can be decreased when used in combination with Dimetotiazine.
DB14740
The therapeutic efficacy of Hyaluronidase can be decreased when used in combination with Dimetotiazine.
DB00182
Amphetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB00191
Phentermine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB00852
Pseudoephedrine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB00865
Benzphetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB00937
Diethylpropion may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01255
Lisdexamfetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01365
Mephentermine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01442
MMDA may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01454
Midomafetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01467
2,5-Dimethoxy-4-ethylamphetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01484
4-Bromo-2,5-dimethoxyamphetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01509
Tenamfetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01556
Chlorphentermine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01566
Methylenedioxyethamphetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01576
Dextroamphetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB01577
Metamfetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB09480
Iofetamine I-123 may decrease the sedative and stimulatory activities of Dimetotiazine.
DB12080
Ritobegron may decrease the sedative and stimulatory activities of Dimetotiazine.
DB13108
Mephedrone may decrease the sedative and stimulatory activities of Dimetotiazine.
DB13624
Methoxyphenamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB13703
Gepefrine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB13940
2,5-Dimethoxy-4-ethylthioamphetamine may decrease the sedative and stimulatory activities of Dimetotiazine.
DB11642
The therapeutic efficacy of Pitolisant can be decreased when used in combination with Dimetotiazine.

序列

实验性质

外部标识符

resource：ChEBI
identifier：135616
resource：PubChem Compound
identifier：3089
resource：PubChem Substance
identifier：310264930
resource：ChemSpider
identifier：2979
resource：Wikipedia
identifier：Dimetotiazine
resource：ChEMBL
identifier：CHEMBL346977
resource：RxCUI
identifier：50138

外部链接

路径

目标

酶

载体

运输工具

药物反应

效应

不良反应