ID

DB08987||

名称

Etidocaine

描述

Etidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage of increased bleeding during oral surgery.

cas号

36637-18-0

唯一标识码

I6CQM0F31V

状态

solid

组

approved,

指示

药效学

作用机制

毒性

代谢

吸收

半衰期

分类

description:This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids.
direct-parent:Alpha amino acid amides
kingdom:Organic compounds
superclass:Organic acids and derivatives
class:Carboxylic acids and derivatives
subclass:Amino acids, peptides, and analogues
alternative-parent:Anilides
alternative-parent:Carbonyl compounds
alternative-parent:Fatty amides
alternative-parent:Hydrocarbon derivatives
alternative-parent:N-arylamides
alternative-parent:Organic oxides
alternative-parent:Organopnictogen compounds
alternative-parent:Secondary carboxylic acid amides
alternative-parent:Trialkylamines
alternative-parent:m-Xylenes
substituent:Alpha-amino acid amide
substituent:Amine
substituent:Anilide
substituent:Aromatic homomonocyclic compound
substituent:Benzenoid
substituent:Carbonyl group
substituent:Carboxamide group
substituent:Fatty acyl
substituent:Fatty amide
substituent:Hydrocarbon derivative
substituent:M-xylene
substituent:Monocyclic benzene moiety
substituent:N-arylamide
substituent:Organic nitrogen compound
substituent:Organic oxide
substituent:Organic oxygen compound
substituent:Organonitrogen compound
substituent:Organooxygen compound
substituent:Organopnictogen compound
substituent:Secondary carboxylic acid amide
substituent:Tertiary aliphatic amine
substituent:Tertiary amine
substituent:Xylene

消除途径

种类

Acetanilides
D000083
Amides
D000577
Amines
D000588
Anesthetics
D000777
Anesthetics, Local
D000779
Anilides
D000813
Aniline Compounds
D000814
Central Nervous System Agents
D002491
Central Nervous System Depressants
D002492
Local Anesthetics (Amide)

Nervous System
D009420
Peripheral Nervous System Agents
D018373
Sensory System Agents
D018689

盐类

DBSALT001431Etidocaine hydrochlorideG6N3B3U8E636637-19-1LMWQQUMMGGIGJQ-UHFFFAOYSA-N312.88312.1968413

蛋白质结合

清除

同义词

language:spanish; code:inn; name;Etidocaina
language:english; code:inn/ban/usan; name;Etidocaine
language:latin; code:inn; name;Etidocainum

国际品牌

DuranestAstraZeneca

配送量

产品

混合物

包装者

生产者

价格

受影响的生物体

剂量

atc代码

Amides
ANESTHETICS, LOCAL
ANESTHETICS
NERVOUS SYSTEM
Amides
ANESTHETICS, LOCAL
ANESTHETICS
NERVOUS SYSTEM

fda标签

化学品安全技术说明书

专利

食物相互作用

药物相互作用

DB00070
Hyaluronidase (ovine) can cause an increase in the absorption of Etidocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
DB06205
Hyaluronidase (human recombinant) can cause an increase in the absorption of Etidocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
DB14740
Hyaluronidase can cause an increase in the absorption of Etidocaine resulting in an increased serum concentration and potentially a worsening of adverse effects.
DB09266
Etidocaine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.

序列

实验性质

Melting Point
203-203.5
U.S. Patent 3,812,147.

外部标识符

resource：ChEBI
identifier：4904
resource：PubChem Compound
identifier：37497
resource：PubChem Substance
identifier：310264948
resource：KEGG Compound
identifier：C07530
resource：KEGG Drug
identifier：D04095
resource：ChemSpider
identifier：34400
resource：BindingDB
identifier：50225497
resource：Wikipedia
identifier：Etidocaine
resource：ChEMBL
identifier：CHEMBL492
resource：RxCUI
identifier：4171

外部链接

路径

目标

酶

载体

运输工具

药物反应

效应

不良反应