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I. Introduction |
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II. Interdisciplinary Interactions |
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III. The Dynamics of Change |
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IV. The Current Situation |
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A. Clinical Pharmacology |
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B. Clinical Development |
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V. The Need for Change, Rationalization, Efficacy, and Economy |
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A. Prospective Planning |
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B. Discovery |
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C. Nonclinical Development |
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D. Clinical Pharmacology and Clinical Pharmacokinetic Studies |
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E. Clinical Development |
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VI. Summary and Conclusions |
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References |
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