DISEASE: Uropathogenic Escherichia coli (UPEC) infection


Entry
H00279                      Disease                                
Name
Uropathogenic Escherichia coli (UPEC) infection
Description
Uropathogenic Escherichia coli (UPEC) infection is a prevalent infectious disease with potentially severe complications. UPEC, the most common etiological agent of community-acquired urinary tract infections (UTIs), accounts for >80% of UTI infections worldwide. Once inside the urinary tract, UPEC preferentially colonizes the bladder and causes cystitis, but can also ascend through the ureters into the kidneys, causing pyelonephritis.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by enterobacteria
   H00279  Uropathogenic Escherichia coli (UPEC) infection
Human diseases in ICD-11 classification [BR:br08403]
 16 Diseases of the genitourinary system
  Diseases of the urinary system
   Certain specified diseases of urinary system
    GC08  Urinary tract infection, site not specified
     H00279  Uropathogenic Escherichia coli (UPEC) infection
Pathogen
Escherichia coli (UPEC) [GN:ecp ena ecos eum ect eci ecc ecoj]
pore-forming toxin [KO:K11003 K11004 K11005]
Other DBs
ICD-11: GC08.0
ICD-10: N39
MeSH: D004927
Reference
PMID:9551528
  Authors
Matsumoto T
  Title
[Virulence factors and host responses in urinary tract infections].
  Journal
J UOEH 20:45-60 (1998)
DOI:10.7888/juoeh.20.45
Reference
PMID:16100859
  Authors
Mehnert-Kay SA
  Title
Diagnosis and management of uncomplicated urinary tract infections.
  Journal
Am Fam Physician 72:451-6 (2005)
Reference
PMID:16406777
  Authors
Svanborg C, Bergsten G, Fischer H, Godaly G, Gustafsson M, Karpman D, Lundstedt AC, Ragnarsdottir B, Svensson M, Wullt B
  Title
Uropathogenic Escherichia coli as a model of host-parasite interaction.
  Journal
Curr Opin Microbiol 9:33-9 (2006)
DOI:10.1016/j.mib.2005.12.012
Reference
PMID:17458672
  Authors
Yamamoto S
  Title
Molecular epidemiology of uropathogenic Escherichia coli.
  Journal
J Infect Chemother 13:68-73 (2007)
DOI:10.1007/s10156-007-0506-y
Reference
PMID:18482721
  Authors
Wiles TJ, Kulesus RR, Mulvey MA
  Title
Origins and virulence mechanisms of uropathogenic Escherichia coli.
  Journal
Exp Mol Pathol 85:11-9 (2008)
DOI:10.1016/j.yexmp.2008.03.007
Reference
PMID:18616559
  Authors
Dhakal BK, Kulesus RR, Mulvey MA
  Title
Mechanisms and consequences of bladder cell invasion by uropathogenic Escherichia coli.
  Journal
Eur J Clin Invest 38 Suppl 2:2-11 (2008)
DOI:10.1111/j.1365-2362.2008.01986.x

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