Aggregatibacter aphrophilus (formerly Haemophilus aphrophilus) is a capnophilic, fermentative, non-motile, gram-negative coccobacillus, that is part of the indigenous microbiota of the human oropharynx. Infections with this bacterium are infrequent. It has mainly been associated with endocarditis, brain abscesses, vertebral osteomyelitis, and bacteremia.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
Bacterial infections
Infections caused by other gamma proteobacteria
H01068 Aggregatibacter aphrophilus infection
Pathogen
Aggregatibacter aphrophilus [GN:aap]
Comment
Resistance to ampicillin, cefuroxime, ceftazidime and cefotaxime has been reported, with clinical failure of treatment with third-generation cephalosporins.
Reference
PMID:6816135
Authors
Albritton WL
Title
Infections due to Haemophilus species other than H. influenzae.
Journal
Annu Rev Microbiol 36:199-216 (1982) DOI:10.1146/annurev.mi.36.100182.001215
Reference
PMID:11318807
Authors
Colson P, La Scola B, Champsaur P
Title
Vertebral infections caused by Haemophilus aphrophilus: case report and review.