DISEASE: Meningococcal infection

Entry

H00314                      Disease

Name

Meningococcal infection

Description

Neisseria meningitidis is a gram-negative bacterial pathogen that specifically infects humans. It is a frequent asymptomatic colonizer of the human upper respiratory tract, and most adults are resistant to infection through acquired immunity. In susceptible individuals, it causes meningococcal meningitis and severe septicemia.

Category

Infectious disease

Brite

Infectious diseases [BR:br08401]
Bacterial infections
  Infections caused by beta proteobacteria
   H00314  Meningococcal infection
Human diseases in ICD-11 classification [BR:br08403]
01 Certain infectious or parasitic diseases
  Other bacterial diseases
   1C1C  Meningococcal disease
    H00314  Meningococcal infection

Pathogen

Neisseria meningitidis serogroup A [GN:nma nmw nmx]
Neisseria meningitidis serogroup B [GN:nme nmh nmd nmm nms nmq nmz]
Neisseria meningitidis serogroup C [GN:nmc nmn nmt]

Drug

Penicillin G potassium [DR:D01053]
Sulfadiazine [DR:D00587]

Comment

Antibiotic resistance in N. meningitidis ash been reported.

Other DBs

ICD-11:

1C1C

ICD-10:

A39

MeSH:

D008589

Reference

PMID:19287450

Authors

Virji M

Title

Pathogenic neisseriae: surface modulation, pathogenesis and infection control.

Journal

Nat Rev Microbiol 7:274-86 (2009)
DOI:10.1038/nrmicro2097

Reference

PMID:12150701

Authors

Foster C, Nadel S

Title

New therapies and vaccines for bacterial meningitis.

Journal

Expert Opin Investig Drugs 11:1051-60 (2002)
DOI:10.1517/13543784.11.8.1051

Reference

PMID:22085175

Authors

Safadi MA, McIntosh ED

Title

Epidemiology and prevention of meningococcal disease: a critical appraisal of vaccine policies.

Journal

Expert Rev Vaccines 10:1717-30 (2011)
DOI:10.1586/erv.11.159

Reference

PMID:21832882

Authors

Yogev R, Tan T

Title

Meningococcal disease: the advances and challenges of meningococcal disease prevention.

Journal

Hum Vaccin 7:828-37 (2011)
DOI:10.4161/hv.7.8.16270

» Japanese version

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Ontology (1)   
   KEGG BRITE (1)   
Drug (4)   
   KEGG DRUG (4)   
Genome (13)   
   KEGG GENOME (13)   
Literature (4)   
   PubMed (4)   
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