Glanders is an infectious disease of equines that can be transmitted to humans. It is usually an occupational disease, affecting individuals in contact with infected animals such as veterinarians, grooms, and farmers. The causative agent of glanders is Burkholderia mallei, a gram-negative aerobic bacterium. In equines and humans, B. mallei infection can present as either nasal-pulmonary infections (glanders) or cutaneous infections (farcy).
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
Bacterial infections
Infections caused by beta proteobacteria
H00316 Glanders
Human diseases in ICD-11 classification [BR:br08403]
01 Certain infectious or parasitic diseases
Certain zoonotic bacterial diseases
1B92 Glanders
H00316 Glanders
Pathogen
Burkholderia mallei [GN:bma bmn]
Other DBs
ICD-11:
1B92
ICD-10:
A24.0
MeSH:
D005896
Reference
PMID:19585782
Authors
Larsen JC, Johnson NH
Title
Pathogenesis of Burkholderia pseudomallei and Burkholderia mallei.
Journal
Mil Med 174:647-51 (2009)
Reference
PMID:18221181
Authors
Gilad J
Title
Burkholderia mallei and Burkholderia pseudomallei: the causative micro-organisms of glanders and melioidosis.
Journal
Recent Pat Antiinfect Drug Discov 2:233-41 (2007) DOI:10.2174/157489107782497335
Reference
PMID:20528691
Authors
Galyov EE, Brett PJ, DeShazer D
Title
Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis.
Journal
Annu Rev Microbiol 64:495-517 (2010) DOI:10.1146/annurev.micro.112408.134030
Reference
PMID:22398248
Authors
Waag DM, England MJ, DeShazer D
Title
Humoral immune responses in a human case of glanders.