DISEASE: Melioidosis


Entry
H00317                      Disease                                
Name
Melioidosis
Description
Melioidosis is an infection caused by the gram-negative soil-dwelling bacillus Burkholderia pseudomallei. It predominantly affects people in regular contact with soil and water and is endemic in areas of Southeast Asia and Northern Australia. There are many possible disease manifestations including melioidosis septic shock, pneumonia, and hepatic and splenic abscesses.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by beta proteobacteria
   H00317  Melioidosis
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Other bacterial diseases
   1C42  Melioidosis
    H00317  Melioidosis
Related
pathway
hsa04620  Toll-like receptor signaling pathway
Gene
TLR5 (resistance) [HSA:7100] [KO:K10168]
Pathogen
Burkholderia pseudomallei [GN:bps bpm bpl bpd bpr bpse bpz bpq]
Other DBs
ICD-11: 1C42
ICD-10: A24.1 A24.2 A24.3 A24.4
MeSH: D008554
OMIM: 615557
Reference
PMID:21558159
  Authors
Limmathurotsakul D, Peacock SJ
  Title
Melioidosis: a clinical overview.
  Journal
Br Med Bull 99:125-39 (2011)
DOI:10.1093/bmb/ldr007
Reference
PMID:16541135
  Authors
Wiersinga WJ, van der Poll T, White NJ, Day NP, Peacock SJ
  Title
Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei.
  Journal
Nat Rev Microbiol 4:272-82 (2006)
DOI:10.1038/nrmicro1385
Reference
PMID:23447684 (TLR5)
  Authors
West TE, Chantratita N, Chierakul W, Limmathurotsakul D, Wuthiekanun V, Myers ND, Emond MJ, Wurfel MM, Hawn TR, Peacock SJ, Skerrett SJ
  Title
Impaired TLR5 functionality is associated with survival in melioidosis.
  Journal
J Immunol 190:3373-9 (2013)
DOI:10.4049/jimmunol.1202974

» Japanese version

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Disease (1)   
   OMIM (1)   
Genome (8)   
   KEGG GENOME (8)   
Gene (2)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
Literature (3)   
   PubMed (3)   
All databases (15)   

Download RDF