DISEASE: Anthrax


Entry
H00328                      Disease                                
Name
Anthrax
Description
Anthrax is a zoonotic infectious disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium belonging to the Bacillus cereus group of pathogenic Bacillus, which also includes a food poisoning bacterium Bacillus cereus [DS:H00329] and an insect pathogen Bacillus thuringiensis [DS:H01399]. Human infections can occur from infected animals or animal products through three main routes: skin (cutaneous), lung (inhalation) and mouth (gastrointestinal). The disease is rare, but the potential threat of anthrax spores in bioterrorism is widely recognized.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by Gram-positive bacteria
   H00328  Anthrax
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Certain zoonotic bacterial diseases
   1B97  Anthrax
    H00328  Anthrax
Pathogen
Bacillus anthracis [GN:ban bar bat bai bax bans]
Bacillus cereus [GN:bal]
  Module
M00859  Bacillus anthracis pathogenicity signature, anthrax toxin
M00860  Bacillus anthracis pathogenicity signature, polyglutamic acid capsule biosynthesis
Drug
Tetracycline hydrochloride [DR:D02122]
Doxycycline [DR:D00307]
Doxycycline hyclate [DR:D02129]
Doxycycline calcium [DR:D03903]
Minocycline hydrochloride [DR:D00850]
Demeclocycline hydrochloride [DR:D00290]
Penicillin G potassium [DR:D01053]
Penicillin G procaine [DR:D02461]
Penicillin G sodium [DR:D05408]
Ciprofloxacin [DR:D00186]
Ciprofloxacin hydrochloride [DR:D02216]
Levofloxacin [DR:D00588]
Raxibacumab [DR:D05706]
Obiltoxaximab [DR:D10776]
Other DBs
ICD-11: 1B97
ICD-10: A22
MeSH: D000881
MedlinePlus: 001325
Reference
PMID:21852539
  Authors
Sweeney DA, Hicks CW, Cui X, Li Y, Eichacker PQ
  Title
Anthrax infection.
  Journal
Am J Respir Crit Care Med 184:1333-41 (2011)
DOI:10.1164/rccm.201102-0209CI
Reference
PMID:21777993
  Authors
Aquino LL, Wu JJ
  Title
Cutaneous manifestations of category A bioweapons.
  Journal
J Am Acad Dermatol 65:1213.e1-1213.e15 (2011)
DOI:10.1016/j.jaad.2010.08.040

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG MODULE (2)   
Drug (18)   
   KEGG DRUG (18)   
Genome (7)   
   KEGG GENOME (7)   
Literature (2)   
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