Bacillus thuringiensis is a close taxonomic relative of Bacillus cereus and an insect pathogen that is widely used as a biopesticide. Additionally, this bacterium is known to induce myonecrosis in immunosuppressed mice after cutaneous infection. Human infection is unusual, and apart from gastrointestinal tract infections or those following laboratory contamination, there are only two clinical reports of B. thuringiensis infection. Both the cases were isolated from severe human tissue necrosis by burn wounds or severe war wounds.
Characterization of Bacillus thuringiensis isolated from infections in burn wounds.
Journal
FEMS Immunol Med Microbiol 18:47-53 (1997) DOI:10.1111/j.1574-695X.1997.tb01026.x
Reference
PMID:10340711
Authors
Hernandez E, Ramisse F, Cruel T, le Vagueresse R, Cavallo JD
Title
Bacillus thuringiensis serotype H34 isolated from human and insecticidal strains serotypes 3a3b and H14 can lead to death of immunocompetent mice after pulmonary infection.
Journal
FEMS Immunol Med Microbiol 24:43-7 (1999) DOI:10.1111/j.1574-695X.1999.tb01263.x
Reference
PMID:9650985
Authors
Hernandez E, Ramisse F, Ducoureau JP, Cruel T, Cavallo JD
Title
Bacillus thuringiensis subsp. konkukian (serotype H34) superinfection: case report and experimental evidence of pathogenicity in immunosuppressed mice.