DISEASE: Dengue


Entry
H00381                      Disease                                
Name
Dengue
  Supergrp
Mosquito-borne viral fever [DS:H00382]
Arthropod-borne viral fever [DS:H00383]
Description
Dengue is an infectious disease caused by Dengue virus (DENV), a flavivirus in the Flaviviridae family of +ssRNA viruses, and transmitted by Aedes mosquitoes. Dengue is the most prevalent arboviral infection worldwide, and at least four different serotypes of DENV are known causing dengue fever and life-threatening dengue hemorrhagic fever. Dengue is a very old disease with a report of dengue-like illness in China as early as the third century.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Viral infections
  Infections caused by +ssRNA viruses
   H00381  Dengue
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Dengue
   1D20  Dengue without warning signs
    H00381  Dengue
   1D21  Dengue with warning signs
    H00381  Dengue
   1D22  Severe dengue
    H00381  Dengue
   1D2Z  Dengue fever, unspecified
    H00381  Dengue
Pathogen
Dengue virus 1 [GN:T40048]
Dengue virus 2 [GN:T40373]
Dengue virus 3 [GN:T40374]
Dengue virus 4 [GN:T40375]
Drug
Dengue tetravalent vaccine, live [DR:D12227]
Other DBs
ICD-11: 1D20 1D21 1D22 1D2Z
ICD-10: A97
MeSH: D003715
MedlinePlus: 001374 001373
Reference
PMID:21781999
  Authors
Whitehorn J, Simmons CP
  Title
The pathogenesis of dengue.
  Journal
Vaccine 29:7221-8 (2011)
DOI:10.1016/j.vaccine.2011.07.022
Reference
PMID:11590668
  Authors
Kurane I, Takasaki T
  Title
Dengue fever and dengue haemorrhagic fever: challenges of controlling an enemy still at large.
  Journal
Rev Med Virol 11:301-11 (2001)
DOI:10.1002/rmv.324
Reference
PMID:19460319
  Authors
Weaver SC, Vasilakis N
  Title
Molecular evolution of dengue viruses: contributions of phylogenetics to understanding the history and epidemiology of the preeminent arboviral disease.
  Journal
Infect Genet Evol 9:523-40 (2009)
DOI:10.1016/j.meegid.2009.02.003

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Ontology (1)   
   KEGG BRITE (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (8)   
   KEGG GENOME (4)   
   Virus-HostDB (4)   
Literature (3)   
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