DISEASE: Rabies

Entry

H00377                      Disease

Name

Rabies

Description

Rabies is a typical zoonotic disease caused by rabies virus that belong to the genus Lyssavirus, within the family Rhabdoviridae and the order Mononegavirales of -ssRNA viruses. Dogs are the major vectors. Rabies affects the central nervous system and causes fatal encephalomyelitis.

Category

Infectious disease

Brite

Infectious diseases [BR:br08401]
Viral infections
  Infections caused by -ssRNA viruses
   H00377  Rabies
Human diseases in ICD-11 classification [BR:br08403]
01 Certain infectious or parasitic diseases
  Viral infections of the central nervous system
   1C82  Rabies
    H00377  Rabies

Pathogen

Rabies virus (RABV) [GN:T40022]

Drug

Rabies vaccine [DR:D06504]

Comment

Preexposure vaccination with modern cell culture vaccine is recommended for people at high risk of exposure. Postexposure prophylaxis consists of wound cleansing and immunization with modern cell culture vaccine, together with administration of rabies immune globulin. There is no certain cure for rabies except supportive care.

Other DBs

ICD-11:

1C82

ICD-10:

A82

MeSH:

D011818

MedlinePlus:

001334

Reference

PMID:22348291

Authors

Yousaf MZ, Qasim M, Zia S, Khan Mu, Ashfaq UA, Khan S

Title

Rabies molecular virology, diagnosis, prevention and treatment.

Journal

Virol J 9:50 (2012)
DOI:10.1186/1743-422X-9-50

Reference

PMID:18297443

Authors

Takayama N

Title

Rabies: a preventable but incurable disease.

Journal

J Infect Chemother 14:8-14 (2008)
DOI:10.1007/s10156-007-0573-0

Reference

PMID:18165217

Authors

Leung AK, Davies HD, Hon KL

Title

Rabies: epidemiology, pathogenesis, and prophylaxis.

Journal

Adv Ther 24:1340-7 (2007)
DOI:10.1007/BF02877781

» Japanese version

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Ontology (1)   
   KEGG BRITE (1)   
Drug (2)   
   KEGG DRUG (2)   
Genome (2)   
   KEGG GENOME (1)   
   Virus-HostDB (1)   
Literature (3)   
   PubMed (3)   
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