Human monkeypox is a rare viral zoonotic disease caused by Monkeypox virus of the genus Orthopoxvirus. It occurs mostly in the rain forests of central and western Africa. Human monkeypox has a clinical presentation similar to that of smallpox, including characteristic rash. Lymphadenopathy is not a common feature of smallpox and is therefore a key distinguishing feature of monkeypox. By contrast with smallpox, human monkeypox has low transmissibility between human beings.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
Viral infections
Infections caused by dsDNA viruses
H00373 Monkeypox
Human diseases in ICD-11 classification [BR:br08403]
01 Certain infectious or parasitic diseases
Viral infections characterised by skin or mucous membrane lesions
Infections due to poxvirus
1E71 Monkeypox
H00373 Monkeypox
Pathogen
Monkeypox virus [GN:T40083]
Comment
Many animals are infected with monkeypox virus under natural conditions, including squirrels, non-human primates, and rats. However, the primary reservoir for human infection remains unknown.
Other DBs
ICD-11:
1E71
ICD-10:
B04
MeSH:
D045908
Reference
PMID:6304185
Authors
Jezek Z, Gromyko AI, Szczeniowski MV
Title
Human monkeypox.
Journal
J Hyg Epidemiol Microbiol Immunol 27:13-28 (1983)
Reference
PMID:16288402
Authors
Nalca A, Rimoin AW, Bavari S, Whitehouse CA
Title
Reemergence of monkeypox: prevalence, diagnostics, and countermeasures.