Eosinophilic gastrointestinal disorder (EGID) is a disorder characterised by eosinophilic infiltration of the gastrointestinal tract. The most common form of EGID is Eosinophilic Esophagitis (EoE). Other forms of EGID include eosinophilic gastritis, eosinophilic enteritis, eosinophilic colitis and eosinophilic gastroenteritis (EGE). While these disorders are less frequent than EoE, their pathogenesis and treatment are probably similar. Clinically, patients with EGID often present with dysphagia, vomiting or abdominal pain. While the etiology remains unclear, there is a well documented association of atopy with EGID. Clinical studies in children and adults have demonstrated an association with food allergy.
Category
Immune system disease; Digestive system disease
Brite
Human diseases [BR:br08402]
Immune system diseases
Allergies and autoimmune diseases
H01782 Eosinophilic gastrointestinal disorder
Digestive system diseases
Gastrointestinal diseases
H01782 Eosinophilic gastrointestinal disorder
Comment
See also H01361 Eosinophilic esophagitis.
Other DBs
ICD-10:
K20 K52.8
MeSH:
D057765 C535952
OMIM:
610247 613412
Reference
PMID:24813518
Authors
Prussin C
Title
Eosinophilic gastroenteritis and related eosinophilic disorders.
Journal
Gastroenterol Clin North Am 43:317-27 (2014) DOI:10.1016/j.gtc.2014.02.013
Reference
PMID:22792476
Authors
Jawairia M, Shahzad G, Mustacchia P
Title
Eosinophilic gastrointestinal diseases: review and update.