DISEASE: Thyroid eye disease

Entry

H02402                      Disease

Name

Thyroid eye disease;
Graves ophthalmopathy

Description

Thyroid eye disease (TED), also called Graves ophthalmopathy, is an autoimmune disorder of the retrobulbar tissue. It is the most frequent extrathyroidal manifestation of Graves disease [DS:H00082]. Although TED is often associated with hyperthyroidism, it may occur in primary hypothyroidism, and sometimes in euthyroid individuals.

Category

Immune system disease

Brite

Human diseases [BR:br08402]
Immune system diseases
  Allergies and autoimmune diseases
   H02402  Thyroid eye disease
Human diseases in ICD-11 classification [BR:br08403]
05 Endocrine, nutritional or metabolic diseases
  Endocrine diseases
   Disorders of the thyroid gland or thyroid hormones system
    5A02  Thyrotoxicosis
     H02402  Thyroid eye disease

Drug

Teprotumumab [DR:D09680]

Other DBs

ICD-11:

5A02.0

ICD-10:

E05.0

MeSH:

D049970

OMIM:

275000

Reference

PMID:27701774

Authors

Weiler DL

Title

Thyroid eye disease: a review.

Journal

Clin Exp Optom 100:20-25 (2017)
DOI:10.1111/cxo.12472

Reference

PMID:25606151

Authors

Mallika P, Tan A, Aziz S, Alwi SS, Chong M, Vanitha R, Intan G

Title

Thyroid associated ophthalmopathy - a review.

Journal

Malays Fam Physician 4:8-14 (2009)

Reference

PMID:11502779

Authors

Marcocci C, Bartalena L, Tanda ML, Manetti L, Dell'Unto E, Rocchi R, Barbesino G, Mazzi B, Bartolomei MP, Lepri P, Cartei F, Nardi M, Pinchera A

Title

Comparison of the effectiveness and tolerability of intravenous or oral glucocorticoids associated with orbital radiotherapy in the management of severe Graves' ophthalmopathy: results of a prospective, single-blind, randomized study.

Journal

J Clin Endocrinol Metab 86:3562-7 (2001)
DOI:10.1210/jcem.86.8.7737

» Japanese version

All links

Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Literature (3)   
   PubMed (3)   
All databases (5)   

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