C00116

Entry

C00116                      Compound

Name

Glycerol;
Glycerin;
1,2,3-Trihydroxypropane;
1,2,3-Propanetriol

Formula

C3H8O3

Exact mass

92.0473

Mol weight

92.0938

Structure

Remark

Same as:

D00028

Reaction

R00841 R00847 R00850 R01034 R01036 R01039 R01041 R01043
R01044 R01045 R01047 R01104 R01350 R01351 R01352 R02591
R03331 R03616 R07293 R07298 R07390 R08372 R08658 R10563
R11127 R12243

Pathway

map00040

Pentose and glucuronate interconversions

map00052

Galactose metabolism

map00561

Glycerolipid metabolism

map01100

Metabolic pathways

map02010

ABC transporters

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map04923

Regulation of lipolysis in adipocytes

Module

M00098

Acylglycerol degradation

M00630

D-Galacturonate degradation (fungi), D-galacturonate => glycerol

Enzyme

1.1.1.2         1.1.1.6         1.1.1.21        1.1.1.72
1.1.1.156       1.1.1.372       1.1.99.22       2.4.1.332
2.4.1.359       2.7.1.30        2.7.1.79        2.7.1.142
2.7.8.-         3.1.1.23        3.1.1.34        3.1.1.79
3.1.3.19        3.1.3.21        3.1.4.38        3.1.4.43
3.2.1.22        3.2.1.-         4.2.1.30

Brite

Compounds with biological roles [BR:br08001]
Carbohydrates
  Monosaccharides
   Sugar alcohols
    C00116  Glycerol
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
  A06 DRUGS FOR CONSTIPATION
   A06A DRUGS FOR CONSTIPATION
    A06AG Enemas
     A06AG04 Glycerol
      D00028  Glycerin (JP18/USP) <JP>
    A06AX Other drugs for constipation
     A06AX01 Glycerol
      D00028  Glycerin (JP18/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2  Agents affecting individual organs
  23  Digestive organ agents
   235  Purgatives, clysters
    2357  Glycerins
     D00028  Glycerin (JP18/USP); Concentrated glycerin (JP18); Glycerin, concentrated (JAN); Glycerol (INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for digestive organs
  18 Enema
   D00028  Glycerin (JP18/USP)
Agents for integumentary system
  55 Chilblain and chap remedies
   D00028  Glycerin (JP18/USP)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
  Inorganic and organic chemicals
   Glycerin
    D00028  Glycerin (JP18/USP)
Third-class OTC drugs
  Inorganic and organic chemicals
   Glycerin
    D00028  Glycerin (JP18/USP)
Animal drugs in Japan [BR:br08331]
93  Agents affecting digestive organs
  937  Clysters
   9371  Glycerine and preparations
    C00116  Glycerine
Drug groups [BR:br08330]
Gastrointestinal agent
  DG01770  Laxative
   D00028  Glycerin
Drug classes [BR:br08332]
Gastrointestinal agent
  DG01770  Laxative
   D00028  Glycerin
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
  D00028  Glycerin
  D00028  Concentrated glycerin

Other DBs

CAS:

56-81-5

PubChem:

3416

ChEBI:

17754

KNApSAcK:

C00001163

PDB-CCD:

GOL[PDBj]

3DMET:

B00032

NIKKAJI:

J1.916J

KCF data

ATOM        6
            1   C1c C    20.1415  -20.1600
            2   C1b C    20.1357  -18.7600
            3   C1b C    20.1357  -21.5600
            4   O1a O    18.7415  -20.1542
            5   O1a O    21.5357  -18.7600
            6   O1a O    21.5357  -21.5600
BOND        5
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 1