Folic acid


Entry
D00070                      Drug                                   
Name
Folic acid (JP18/USP/INN);
Folicet (TN)
Product
  Generic
FOLIC ACID (A-S Medication Solutions), FOLIC ACID (A-S Medication Solutions), FOLIC ACID (A-S Medication Solutions), FOLIC ACID (A-S Medication Solutions), FOLIC ACID (A-S Medication Solutions), FOLIC ACID (AiPing Pharmaceutical), FOLIC ACID (AiPing Pharmaceutical), FOLIC ACID (American Health Packaging), FOLIC ACID (American Health Packaging), FOLIC ACID (Amneal Pharmaceuticals LLC), FOLIC ACID (Amneal Pharmaceuticals of New York LLC), FOLIC ACID (Aphena Pharma Solutions - Tennessee), FOLIC ACID (Aphena Pharma Solutions - Tennessee), FOLIC ACID (Aphena Pharma Solutions - Tennessee), FOLIC ACID (Aphena Pharma Solutions - Tennessee), FOLIC ACID (Athem LLC), FOLIC ACID (AvPAK), FOLIC ACID (Bryant Ranch Prepack), FOLIC ACID (Bryant Ranch Prepack), FOLIC ACID (Bryant Ranch Prepack), FOLIC ACID (Bryant Ranch Prepack), FOLIC ACID (Cadila Pharmaceuticals Limited), FOLIC ACID (Cardinal Health), FOLIC ACID (Chartwell RX), FOLIC ACID (Clinical Solutions Wholesale), FOLIC ACID (DIRECT RX), FOLIC ACID (Denton Pharma), FOLIC ACID (Denton Pharma), FOLIC ACID (Denton Pharma), FOLIC ACID (ECI PHARMACEUTICALS LLC), FOLIC ACID (Fresenius Kabi USA), FOLIC ACID (Leading Pharma), FOLIC ACID (Major Pharmaceuticals), FOLIC ACID (Marlex Pharmaceuticals), FOLIC ACID (McKesson Corporation dba SKY Packaging), FOLIC ACID (Method Pharmaceuticals), FOLIC ACID (NCS HealthCare of KY), FOLIC ACID (NCS HealthCare of KY), FOLIC ACID (NuCare Pharmaceuticals), FOLIC ACID (NuCare Pharmaceuticals), FOLIC ACID (NuCare Pharmaceuticals), FOLIC ACID (NuCare Pharmaceuticals), FOLIC ACID (NuCare Pharmaceuticals), FOLIC ACID (PD-Rx Pharmaceuticals), FOLIC ACID (PD-Rx Pharmaceuticals), FOLIC ACID (Preferred Pharmaceuticals), FOLIC ACID (Preferred Pharmaceuticals), FOLIC ACID (Proficient Rx LP), FOLIC ACID (REMEDYREPACK), FOLIC ACID (REMEDYREPACK), FOLIC ACID (REMEDYREPACK), FOLIC ACID (REMEDYREPACK), FOLIC ACID (SUNRISE PHARMACEUTICAL), FOLIC ACID (XGen Pharmaceuticals DJB)
Formula
C19H19N7O6
Exact mass
441.1397
Mol weight
441.3975
Structure
Simcomp
Remark
Same as: C00504
Therapeutic category: 3135
ATC code: B03BB01 V04CX02
Chemical structure group: DG00176
Product (DG00176): D00070<JP/US>
Product (mixture): D08830<JP>
Efficacy
Anti-anemic, Hematopoietic, Supplement (folic acid)
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B03 ANTIANEMIC PREPARATIONS
   B03B VITAMIN B12 AND FOLIC ACID
    B03BB Folic acid and derivatives
     B03BB01 Folic acid
      D00070  Folic acid (JP18/USP/INN) <JP/US>
 V VARIOUS
  V04 DIAGNOSTIC AGENTS
   V04C OTHER DIAGNOSTIC AGENTS
    V04CX Other diagnostic agents
     V04CX02  Folic acid
      D00070  Folic acid (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Electrolytes/Minerals/Metals/Vitamins
  Vitamins
   Folic Acid
    D00070  Folic acid (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  31  Vitamins
   313  Vitamin B preparations
    3135  Folic acids
     D00070  Folic acid (JP18/USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for circulatory system and blood
  24 Anemia drugs
   D00070  Folic acid (JP18/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Folic acid
    D00070  Folic acid (JP18/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00070  Folic acid
  D00070  Folic acid tablets
  D00070  Folic acid injection
Other DBs
CAS: 59-30-3
PubChem: 7847138
ChEBI: 27470
PDB-CCD: FOL[PDBj]
LigandBox: D00070
NIKKAJI: J1.392G
KCF data

ATOM        32
            1   C8y C    15.5904  -18.4449
            2   C8y C    15.5904  -17.0418
            3   N5x N    16.8180  -19.1464
            4   N5x N    14.3803  -19.1522
            5   N5x N    16.8123  -16.3228
            6   C8y C    14.3803  -16.3461
            7   C8x C    18.0458  -18.4507
            8   C8y C    13.1702  -18.4449
            9   C8y C    18.0341  -17.0301
            10  N4x N    13.1702  -17.0418
            11  O5x O    14.3745  -14.9549
            12  N1a N    11.9659  -19.1347
            13  C1b C    19.2325  -16.3286
            14  N1b N    20.4427  -17.0242
            15  C8y C    21.6528  -16.3228
            16  C8x C    22.8570  -17.0184
            17  C8x C    21.6411  -14.9198
            18  C8x C    24.0672  -16.3111
            19  C8x C    22.8453  -14.2182
            20  C8y C    24.0614  -14.9138
            21  C5a C    25.2715  -14.2123
            22  N1b N    26.4817  -14.9081
            23  O5a O    25.2656  -12.8152
            24  C1c C    27.6916  -14.2065
            25  C1b C    28.9077  -14.9021
            26  C6a C    27.6916  -12.8092
            27  C1b C    30.1179  -14.2006
            28  O6a O    28.8960  -12.1077
            29  O6a O    26.4757  -12.1136
            30  C6a C    31.3280  -14.8964
            31  O6a O    32.5381  -14.1948
            32  O6a O    31.3338  -16.2935
BOND        34
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     4   8 2
            8     5   9 2
            9     6  10 1
            10    6  11 2
            11    8  12 1
            12    9  13 1
            13   13  14 1
            14   14  15 1
            15   15  16 2
            16   15  17 1
            17   16  18 1
            18   17  19 2
            19   18  20 2
            20   20  21 1
            21   21  22 1
            22   21  23 2
            23   22  24 1
            24   24  25 1
            25   24  26 1 #Down
            26   25  27 1
            27   26  28 1
            28   26  29 2
            29   27  30 1
            30   30  31 1
            31   30  32 2
            32    7   9 1
            33    8  10 1
            34   19  20 1