| Entry |
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| Name | Naproxen (JP18/USP/INN); Naprosyn (TN) | ||||||||||||
| Product | NAPROXEN (Acella Pharmaceuticals), NAPROXEN (Allegis Holdings), NAPROSYN (Athena Bioscience), EC-NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Woodward Pharma Services LLC), NAPROXEN SODIUM (Canton Laboratories) | ||||||||||||
| Generic | NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (A-S Medication Solutions), NAPROXEN (Advanced Rx Pharmacy of Tennessee), NAPROXEN (Advanced Rx Pharmacy of Tennessee), NAPROXEN (Advanced Rx Pharmacy of Tennessee), NAPROXEN (Advanced Rx Pharmacy of Tennessee), NAPROXEN (Advanced Rx Pharmacy of Tennessee), NAPROXEN (Advanced Rx Pharmacy of Tennessee), NAPROXEN (American Health Packaging), NAPROXEN (Amneal Pharmaceuticals LLC), NAPROXEN (Amneal Pharmaceuticals NY LLC), NAPROXEN (Amneal Pharmaceuticals of New York LLC), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Aphena Pharma Solutions - Tennessee), NAPROXEN (Asclemed USA), NAPROXEN (Asclemed USA), NAPROXEN (Aurobindo Pharma Limited), NAPROXEN (AvKARE), NAPROXEN (AvKARE), NAPROXEN (AvPAK), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Bryant Ranch Prepack), NAPROXEN (Cadila Healthcare Limited), NAPROXEN (Camber Pharmaceuticals), NAPROXEN (Cipla USA), NAPROXEN (Cipla USA), NAPROXEN (Clinical Solutions Wholesale), NAPROXEN (Contract Pharmacy Services-PA), NAPROXEN (DIRECT RX), NAPROXEN (DIRECT RX), NAPROXEN (DIRECT RX), NAPROXEN (Denton Pharma), NAPROXEN (Denton Pharma), NAPROXEN (Direct RX), NAPROXEN (DirectRX), NAPROXEN (Direct_Rx), NAPROXEN (Direct_Rx), NAPROXEN (Direct_Rx), NAPROXEN (Direct_Rx), NAPROXEN (Direct_Rx), NAPROXEN (Exelan Pharmaceuticals), NAPROXEN (Hikma Pharmaceuticals USA), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (Lake Erie Medical DBA Quality Care Products LLC), NAPROXEN (MARKSANS PHARMA LIMITED), NAPROXEN (McKesson Corporation dba SKY Packaging), NAPROXEN (Medsource Pharmaceuticals), NAPROXEN (NCS HealthCare of KY), NAPROXEN (Northwind Pharmaceuticals), NAPROXEN (Northwind Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (NuCare Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (PD-Rx Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Preferred Pharmaceuticals), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (Proficient Rx LP), NAPROXEN (QPharma), NAPROXEN (QPharma), NAPROXEN (Quality Care Products), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (REMEDYREPACK), NAPROXEN (RPK Pharmaceuticals), NAPROXEN (RPK Pharmaceuticals), NAPROXEN (RPK Pharmaceuticals), NAPROXEN (RPK Pharmaceuticals), NAPROXEN (Radha Pharmaceuticals), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (RedPharm Drug), NAPROXEN (ST. MARY'S MEDICAL PARK PHARMACY), NAPROXEN (ST. MARY'S MEDICAL PARK PHARMACY), NAPROXEN (ScieGen Pharmaceuticals), NAPROXEN (St. Mary's Medical Park Pharmacy), NAPROXEN (St. Mary's Medical Park Pharmacy), NAPROXEN (St. Mary's Medical Park Pharmacy), NAPROXEN (TIME CAP LABORATORIES), NAPROXEN (Teva Pharmaceuticals USA), NAPROXEN (Unit Dose Services), NAPROXEN (Virtus Pharmaceuticals), NAPROXEN (Zydus Pharmaceuticals (USA)), NAPROXEN (medsource pharmaceuticals), NAPROXEN (medsource pharmaceuticals), NAPROXEN (medsource pharmaceuticals), NAPROXEN ORAL SUSPENSION (Novitium Pharma LLC), NAPROXEN SODIUM (Bryant Ranch Prepack), NAPROXEN SODIUM (Glenmark Pharmaceuticals) | ||||||||||||
| Formula | C14H14O3 | ||||||||||||
| Exact mass | 230.0943 | ||||||||||||
| Mol weight | 230.2592 | ||||||||||||
| Structure |  | ||||||||||||
| Simcomp | |||||||||||||
| Class | Anti-inflammatory DG01504 Nonsteroidal anti-inflammatory drug (NSAID) DG01908 Anti-inflammatory drug, propionic acid derivatives | ||||||||||||
| Remark |
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| Efficacy | Analgesic, Anti-inflammatory, Antipyretic, COX inhibitor | ||||||||||||
| Disease | Rheumatoid arthritis [DS:H00630] Ankylosing spondylitis [DS:H01674] Polyarticular juvenile idiopathic arthritis [DS:H01672] Acute gout [DS:H01532] | ||||||||||||
| Comment | Propionic acid derivative | ||||||||||||
| Target | PTGS1 (COX1) [HSA:5742] [KO:K00509] PTGS2 (COX2) [HSA:5743] [KO:K11987] | ||||||||||||
| Pathway |
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| Interaction | |||||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] G GENITO URINARY SYSTEM AND SEX HORMONES G02 OTHER GYNECOLOGICALS G02C OTHER GYNECOLOGICALS G02CC Antiinflammatory products for vaginal administration G02CC02 Naproxen D00118 Naproxen (JP18/USP/INN) <JP/US> M MUSCULO-SKELETAL SYSTEM M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS M01AE Propionic acid derivatives M01AE02 Naproxen D00118 Naproxen (JP18/USP/INN) <JP/US> M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN M02AA Antiinflammatory preparations, non-steroids for topical use M02AA12 Naproxen D00118 Naproxen (JP18/USP/INN) <JP/US> USP drug classification [BR:br08302] Analgesics Nonsteroidal Anti-inflammatory Drugs Naproxen D00118 Naproxen (JP18/USP/INN) Therapeutic category of drugs in Japan [BR:br08301] 1 Agents affecting nervous system and sensory organs 11 Agents affecting central nervous system 114 Antipyretics and analgesics, anti-inflammatory agents 1149 Others D00118 Naproxen (JP18/USP/INN) Risk category of Japanese OTC drugs [BR:br08312] Drugs requiring guidance New approved switch OTC drugs Naproxen D00118 Naproxen (JP18/USP/INN) Drug groups [BR:br08330] Anti-inflammatory DG01504 Nonsteroidal anti-inflammatory drug (NSAID) DG01908 Anti-inflammatory drug, propionic acid derivatives DG00455 Naproxen D00118 Naproxen Drug classes [BR:br08332] Anti-inflammatory DG01504 Nonsteroidal anti-inflammatory drug (NSAID) D00118 Naproxen Target-based classification of drugs [BR:br08310] Enzymes Oxidoreductases (EC1) Prostaglandin synthase PTGS1 (COX1) D00118 Naproxen (JP18/USP/INN) <JP/US> PTGS2 (COX2) D00118 Naproxen (JP18/USP/INN) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00118 Naproxen Drug groups [BR:br08330] Anti-inflammatory DG01504 Nonsteroidal anti-inflammatory drug (NSAID) DG01908 Anti-inflammatory drug, propionic acid derivatives DG00455 Naproxen | ||||||||||||
| Other DBs |
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| KCF data | ATOM 17 1 C8y C 24.6254 -20.0866 2 C8y C 24.6254 -21.4127 3 C8x C 25.8119 -19.3887 4 C8x C 23.5087 -19.3887 5 C8x C 23.5087 -22.1106 6 C8x C 25.8119 -22.1106 7 C8y C 26.9983 -20.0866 8 C8x C 22.3222 -20.0866 9 C8y C 22.3222 -21.4127 10 C8x C 26.9983 -21.3429 11 C1c C 28.1848 -19.3887 12 O2a O 21.1358 -22.1106 13 C6a C 29.3015 -20.0866 14 C1a C 28.1848 -18.0626 15 C1a C 19.4607 -21.0637 16 O6a O 30.6974 -19.1793 17 O6a O 29.3015 -21.4127 BOND 18 1 1 2 2 2 1 3 1 3 1 4 1 4 2 5 1 5 2 6 1 6 3 7 2 7 4 8 2 8 5 9 2 9 6 10 2 10 7 11 1 11 9 12 1 12 11 13 1 13 11 14 1 #Down 14 12 15 1 15 13 16 1 16 13 17 2 17 7 10 1 18 8 9 1 |