Entry

D00160                      Drug

Name

Aminocaproic acid (USP/INN);
Epsilon-Aminocaproic acid (JAN);
Amicar (TN)

Product

AMICAR (Akorn Operating Company LLC)

Generic

AMINOCAPROIC ACID (ANI Pharmaceuticals), AMINOCAPROIC ACID (Akorn Operating Company LLC), AMINOCAPROIC ACID (American Health Packaging), AMINOCAPROIC ACID (American Regent), AMINOCAPROIC ACID (American Regent), AMINOCAPROIC ACID (Amneal Pharmaceuticals NY LLC), AMINOCAPROIC ACID (Amneal Pharmaceuticals NY LLC), AMINOCAPROIC ACID (Amneal Pharmaceuticals NY LLC), AMINOCAPROIC ACID (BPI LABS LLC), AMINOCAPROIC ACID (Biocon Pharma), AMINOCAPROIC ACID (Biocon Pharma), AMINOCAPROIC ACID (Carnegie Pharmaceuticals), AMINOCAPROIC ACID (Civica), AMINOCAPROIC ACID (Edenbridge Pharmaceuticals LLC.), AMINOCAPROIC ACID (General Injectables and Vaccines), AMINOCAPROIC ACID (Henry Schein), AMINOCAPROIC ACID (Hospira), AMINOCAPROIC ACID (Leading Pharma), AMINOCAPROIC ACID (Leading Pharma), AMINOCAPROIC ACID (Leading Pharma), AMINOCAPROIC ACID (MSN LABORATORIES PRIVATE LIMITED), AMINOCAPROIC ACID (Major Pharmaceuticals), AMINOCAPROIC ACID (Novadoz Pharmaceuticals LLC), AMINOCAPROIC ACID (TruPharma LLC), AMINOCAPROIC ACID (VistaPharm), AMINOCAPROIC ACID (Vitruvias Therapeutics), AMINOCAPROIC ACID (airis PHARMA Private Limited)

Formula

C6H13NO2

Exact mass

131.0946

Mol weight

131.1729

Structure

Simcomp

Class

Blood modifier agent
DG02016  Hemostatics
  DG02012  Antifibrinolytic
   DG01540  Plasmin inhibitor

Remark

Same as:

C02378

ATC code:

B02AA01

Product:

D00160<US>

Efficacy

Antifibrinolytic, Anti-inflammatory, Plasmin inhibitor

Target

PLG [HSA:5340] [KO:K01315]

Pathway

hsa04610

Complement and coagulation cascades

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02A ANTIFIBRINOLYTICS
    B02AA Amino acids
     B02AA01 Aminocaproic acid
      D00160  Aminocaproic acid (USP/INN) <US>
USP drug classification [BR:br08302]
Blood Products and Modifiers
  Hemostasis Agents
   6-Aminocaproic Acid
    D00160  Aminocaproic acid (USP/INN)
Classification of Japanese OTC drugs [BR:br08313]
Agents for ophthalmologic use
  62 General eye drops
   D00160  Aminocaproic acid (USP/INN)
  67 Eyewash
   D00160  Aminocaproic acid (USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
Third-class OTC drugs
  Inorganic and organic chemicals
   Epsilon-Aminocaproic acid
    D00160  Aminocaproic acid (USP/INN)
Drug groups [BR:br08330]
Blood modifier agent
  DG02016  Hemostatics
   DG02012  Antifibrinolytic
    DG01540  Plasmin inhibitor
     D00160  Aminocaproic acid
Target-based classification of drugs [BR:br08310]
Enzymes
  Hydrolases (EC3)
   Serine peptidases
    PLG
     D00160  Aminocaproic acid (USP/INN) <US>

Other DBs

CAS:

60-32-2

PubChem:

7847228

ChEBI:

16586

PDB-CCD:

ACA[PDBj]

LigandBox:

D00160

NIKKAJI:

J1.398F

KCF data

ATOM        9
            1   C1b C    21.8300  -17.6973
            2   C1b C    23.0454  -18.3901
            3   C1b C    20.6147  -18.3960
            4   C6a C    24.2549  -17.6855
            5   C1b C    19.4054  -17.7032
            6   O6a O    25.4702  -18.3843
            7   O6a O    24.2549  -16.2824
            8   C1b C    18.1900  -18.4018
            9   N1a N    16.9747  -17.7090
BOND        8
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     4   6 1
            6     4   7 2
            7     5   8 1
            8     8   9 1