Entry

D00221                      Drug

Name

Acetylcysteine (JP18/USP/INN);
Mucomyst (TN)

Product

ACETYLCYSTEINE (Padagis US LLC)

Generic

ACETYLCYSTEINE (Akorn), ACETYLCYSTEINE (American Regent), ACETYLCYSTEINE (AuroMedics Pharma LLC), ACETYLCYSTEINE (Cadila Healthcare Limited), ACETYLCYSTEINE (Cardinal Health), ACETYLCYSTEINE (Fresenius Kabi USA), ACETYLCYSTEINE (Fresenius Kabi USA), ACETYLCYSTEINE (Fresenius Kabi USA), ACETYLCYSTEINE (Fresenius Kabi USA), ACETYLCYSTEINE (Hospira), ACETYLCYSTEINE (Indoco Remedies Limited), ACETYLCYSTEINE (Sagent Pharmaceuticals), ACETYLCYSTEINE (Sagent Pharmaceuticals), ACETYLCYSTEINE (Zydus Pharmaceuticals (USA)), ACETYLCYSTEINE (Exela Pharma Sciences)

Formula

C5H9NO3S

Exact mass

163.0303

Mol weight

163.1949

Structure

Simcomp

Remark

Same as:

C06809

Therapeutic category:

2233 3929

ATC code:

R05CB01 S01XA08 V03AB23

Chemical structure group:

DG01069

Product (DG01069):

D00221<JP/US>

Efficacy

Antidote (acetaminophen), Mucolytic, Expectorant

Disease

Chronic emphysema [DS:H01714]
Cystic fibrosis [DS:H00218]

Comment

Cysteine derivative

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
  R05 COUGH AND COLD PREPARATIONS
   R05C EXPECTORANTS, EXCL. COMBINATIONS WITH COUGH SUPPRESSANTS
    R05CB Mucolytics
     R05CB01 Acetylcysteine
      D00221  Acetylcysteine (JP18/USP/INN) <JP/US>
S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01X OTHER OPHTHALMOLOGICALS
    S01XA Other ophthalmologicals
     S01XA08 Acetylcysteine
      D00221  Acetylcysteine (JP18/USP/INN) <JP/US>
V VARIOUS
  V03 ALL OTHER THERAPEUTIC PRODUCTS
   V03A ALL OTHER THERAPEUTIC PRODUCTS
    V03AB Antidotes
     V03AB23 Acetylcysteine
      D00221  Acetylcysteine (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Respiratory Tract/Pulmonary Agents
  Respiratory Tract Agents, Other
   Acetylcysteine
    D00221  Acetylcysteine (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
2  Agents affecting individual organs
  22  Respiratory organ agents
   223  Expectorants
    2233  Cysteines
     D00221  Acetylcysteine (JP18/USP/INN)
3  Agents affecting metabolism
  39  Other agents affecting metabolism
   392  Antidotes
    3929  Others
     D00221  Acetylcysteine (JP18/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
  D00221  Acetylcysteine

Other DBs

CAS:

616-91-1

PubChem:

7847288

ChEBI:

28939

PDB-CCD:

SC2[PDBj]

LigandBox:

D00221

NIKKAJI:

J3.309J

KCF data

ATOM        10
            1   C1b C    19.2500  -19.4600
            2   S1a S    20.4400  -20.1600
            3   C1c C    18.0600  -20.1600
            4   C6a C    16.8700  -19.4600
            5   N1b N    18.0600  -21.5600
            6   C5a C    16.8476  -22.2600
            7   C1a C    15.6521  -21.5696
            8   O5a O    16.8475  -23.6598
            9   O6a O    15.6519  -20.1501
            10  O6a O    16.8814  -18.0600
BOND        9
            1     1   2 1
            2     1   3 1
            3     3   4 1
            4     3   5 1 #Down
            5     5   6 1
            6     6   7 1
            7     6   8 2
            8     4   9 1
            9     4  10 2