Amoxicillin


Entry
D00229                      Drug                                   
Name
Amoxicillin (USP);
Amoxicillin hydrate (JP18);
Amoxicilline (INN);
Amoxicillin trihydrate;
Amoxil (TN);
Dispermox (TN);
Pasetocin (TN)
Product
AMOXICILLIN (Proficient Rx LP)
  Generic
AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (A-S Medication Solutions), AMOXICILLIN (Asclemed USA), AMOXICILLIN (Asclemed USA), AMOXICILLIN (Asclemed USA), AMOXICILLIN (Asclemed USA), AMOXICILLIN (Aurobindo Pharma Limited), AMOXICILLIN (Aurobindo Pharma Limited), AMOXICILLIN (Aurobindo Pharma Limited), AMOXICILLIN (Aurobindo Pharma Limited), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Bryant Ranch Prepack), AMOXICILLIN (Cambridge Therapeutics Technologies), AMOXICILLIN (Chartwell Governmental & Specialty RX), AMOXIL (DIRECT RX), AMOXIL (DIRECT RX), AMOXICILLIN (DIRECT RX), AMOXICILLIN (DIRECT RX), AMOXICILLIN (DIRECT RX), AMOXICILLIN (DIRECTRX), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (Denton Pharma), AMOXICILLIN (DirectRx), AMOXIL (Direct_Rx), AMOXICILLIN (Hikma Pharmaceuticals USA), AMOXICILLIN (Hikma Pharmaceuticals USA), AMOXICILLIN (Neopharma), AMOXICILLIN (NorthStar Rx LLC), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (NuCare Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PD-Rx Pharmaceuticals), AMOXICILLIN (PharmPak), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Preferred Pharmaceuticals), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (Proficient Rx LP), AMOXICILLIN (QPharma), AMOXICILLIN (QPharma), AMOXICILLIN (QPharma), AMOXICILLIN (QPharma), AMOXICILLIN (QPharma), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (REMEDYREPACK), AMOXICILLIN (RPK Pharmaceuticals), AMOXICILLIN (RPK Pharmaceuticals), AMOXICILLIN (RPK Pharmaceuticals), AMOXICILLIN (RPK Pharmaceuticals), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (RedPharm Drug), AMOXICILLIN (Rising Health), AMOXICILLIN (Rising Health), AMOXICILLIN (Rising Health), AMOXICILLIN (Sandoz), AMOXICILLIN (Teva Pharmaceuticals USA), AMOXICILLIN (Teva Pharmaceuticals USA), AMOXICILLIN (Teva Pharmaceuticals USA), AMOXICILLIN (Unit Dose Services), AMOXICILLIN (West-Ward Pharmaceuticals Corp)
Formula
C16H19N3O5S. 3H2O
Exact mass
419.1362
Mol weight
419.45
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01713  Penicillin skeleton group
   DG01480  Penicillin
 DG01780  Extended spectrum penicillin
Remark
Therapeutic category: 6131
ATC code: J01CA04
Chemical structure group: DG00520
Product (DG00520): D00229<JP/US>
Product (mixture): D06485<JP/US> D08774<US> D10246<US> D10519<JP> D10520<JP> D10774<JP> D10775<JP/US> D11858<US>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
  Disease
Gonorrhea [DS:H00315]
Helicobacter pylori infection [DS:H00320]
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Structure map
map07011  Penicillins
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01C BETA-LACTAM ANTIBACTERIALS, PENICILLINS
    J01CA Penicillins with extended spectrum
     J01CA04 Amoxicillin
      D00229  Amoxicillin (USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Penicillins
   Amoxicillin
    D00229  Amoxicillin (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6131  Penicillins
     D00229  Amoxicillin (USP); Amoxicillin hydrate (JP18); Amoxicilline (INN)
Animal drugs in Japan [BR:br08331]
 97  Agents against pathogenic micro-organisms and parasites (except biological products and disinfectants)
  976  Antibiotic preparations
   9762  Antibiotic preparations for peroral and feed additive use
    D00229  Amoxicillin hydrate
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01713  Penicillin skeleton group
    DG01480  Penicillin
     DG00520  Amoxicillin
      D00229  Amoxicillin
  DG01780  Extended spectrum penicillin
   DG00520  Amoxicillin
    D00229  Amoxicillin
Drug classes [BR:br08332]
 Antibacterial
  DG01480  Penicillin
   D00229  Amoxicillin
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    D00229  Amoxicillin (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00229  Amoxicillin hydrate
  D00229  Amoxicillin capsules
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01713  Penicillin skeleton group
    DG01480  Penicillin
     DG00520  Amoxicillin
  DG01780  Extended spectrum penicillin
   DG00520  Amoxicillin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Extended spectrum penicillin
    DG00520  Amoxicillin
Other DBs
CAS: 61336-70-7
PubChem: 7847296
ChEBI: 51254
LigandBox: D00229
NIKKAJI: J1.892.001H
KCF data

ATOM        28
            1   C1y C    24.5313  -17.0264
            2   C5x C    24.5313  -18.4300
            3   N1y N    25.9349  -18.4300
            4   C1y C    25.9349  -17.0264
            5   C1y C    27.2683  -18.8510
            6   C1z C    28.1103  -17.7281
            7   S2x S    27.2683  -16.6053
            8   C1a C    29.0929  -18.7107
            9   C1a C    29.0929  -16.7456
            10  C6a C    27.7595  -20.1844
            11  O6a O    29.1630  -20.1844
            12  O6a O    26.9173  -21.3072
            13  N1b N    23.3383  -16.3246
            14  C5a C    22.1452  -17.0264
            15  O5x O    23.3383  -19.1317
            16  O5a O    22.1452  -18.4300
            17  C1c C    20.9268  -16.3295
            18  C8y C    19.7355  -17.0241
            19  N1a N    20.9268  -14.9295
            20  C8x C    18.5230  -16.3241
            21  C8x C    17.3106  -17.0241
            22  C8y C    17.3106  -18.4241
            23  C8x C    18.5230  -19.1241
            24  C8x C    19.7355  -18.4241
            25  O1a O    16.0891  -19.1295
            26  O0  O    34.0923  -18.2711
            27  O0  O    34.0923  -18.2711
            28  O0  O    34.0923  -18.2711
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     3   5 1
            6     5   6 1
            7     6   7 1
            8     4   7 1
            9     6   8 1
            10    6   9 1
            11    5  10 1 #Down
            12   10  11 1
            13   10  12 2
            14    1  13 1 #Up
            15   13  14 1
            16    2  15 2
            17   14  16 2
            18   14  17 1
            19   17  18 1
            20   17  19 1 #Up
            21   18  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   23  24 2
            26   18  24 1
            27   22  25 1
BRACKET     1    32.1300  -19.1800   32.1300  -17.3600
            1    34.5800  -17.3600   34.5800  -19.1800
            1  3
 ORIGINAL  1   27
 REPEAT    1   28  29