Prevention of rejection in renal homotransplantation [DS:H00083] Rheumatoid arthritis [DS:H00630]
Comment
Azathioprine is metabolized to 6-mercaptopurine (6-MP) [DR:D04931]
Interaction
Structure map
map07046
Immunosuppressive agents
map07050
Antirheumatics - DMARDs and biological agents
Other map
map00983
Drug metabolism - other enzymes
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L04 IMMUNOSUPPRESSANTS
L04A IMMUNOSUPPRESSANTS
L04AX Other immunosuppressants
L04AX01 Azathioprine
D00238 Azathioprine (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Immunological Agents
Immunosuppressants
Antimetabolites, Purine
Azathioprine
D00238 Azathioprine (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
3 Agents affecting metabolism
39 Other agents affecting metabolism
399 Miscellaneous
3999 Others
D00238 Azathioprine (JP18/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01985 Disease modifying anti-rheumatic drug (DMARD)
DG00743 Azathioprine
D00238 Azathioprine
Drug classes [BR:br08332]
Antirheumatic agent
DG01985 Disease modifying anti-rheumatic drug (DMARD)
D00238 Azathioprine
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00238 Azathioprine
D00238 Azathioprine tablets
New drug approvals in Europe [br08329.html]
European public assessment reports (EPAR) authorised medicine
D00238
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00238
Drug groups [BR:br08330]
Anti-inflammatory
DG01985 Disease modifying anti-rheumatic drug (DMARD)
DG00743 Azathioprine
Other DBs
CAS:
446-86-6
PubChem:
7847305
ChEBI:
2948
LigandBox:
D00238
NIKKAJI:
J2.047H
KCF data
ATOM 19
1 C8y C 22.2600 -23.0300
2 C8y C 21.0700 -23.7300
3 S2a S 22.2600 -21.6300
4 N5x N 23.4500 -23.7300
5 C8y C 21.0700 -25.1300
6 N4x N 19.7400 -23.2400
7 C8y C 21.0700 -20.9300
8 C8x C 23.4500 -25.1300
9 N5x N 19.7400 -25.5500
10 N5x N 22.2600 -25.8300
11 C8x C 18.9000 -24.4300
12 C8y C 21.0700 -19.5300
13 O3a O 23.5200 -19.5300 #-
14 N2b N 22.2600 -18.8300 #+
15 N5x N 19.7400 -19.1100
16 C8x C 18.9000 -20.2300
17 N4y N 19.7400 -21.3500
18 O3a O 22.2600 -17.4300
19 C1a C 18.5276 -22.0500
BOND 21
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 2 6 1
6 3 7 1
7 4 8 1
8 5 9 1
9 5 10 1
10 6 11 1
11 8 10 2
12 9 11 2
13 7 12 2
14 13 14 1
15 12 14 1
16 12 15 1
17 15 16 2
18 16 17 1
19 7 17 1
20 14 18 2
21 17 19 1