| Entry |
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| Name | Aztreonam (JP18/USP/INN); Azactam (TN) | ||||||||||
| Product | AZACTAM (E.R. Squibb & Sons), CAYSTON (Gilead Sciences) | ||||||||||
| Generic | AZTREONAM (Fresenius Kabi USA), AZTREONAM (Fresenius Kabi USA), AZTREONAM (Fresenius Kabi USA), AZTREONAM (Hospira) | ||||||||||
| Formula | C13H17N5O8S2 | ||||||||||
| Exact mass | 435.0519 | ||||||||||
| Mol weight | 435.4328 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Antibacterial DG01710 beta-Lactam antibiotic DG01454 Monobactam DG01804 Oxyimino beta-lactam | ||||||||||
| Remark |
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| Efficacy | Antibacterial, Cell wall biosynthesis inhibitor | ||||||||||
| Disease | Urinary tract infections [DS:H01176] | ||||||||||
| Target | penicillin binding protein | ||||||||||
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01D OTHER BETA-LACTAM ANTIBACTERIALS J01DF Monobactams J01DF01 Aztreonam D00240 Aztreonam (JP18/USP/INN) <JP/US> USP drug classification [BR:br08302] Antibacterials Antibacterials, Other Aztreonam D00240 Aztreonam (JP18/USP/INN) Respiratory Tract/Pulmonary Agents Cystic Fibrosis Agents Inhaled Anti-infectives Aztreonam D00240 Aztreonam (JP18/USP/INN) Therapeutic category of drugs in Japan [BR:br08301] 6 Agents against pathologic organisms and parasites 61 Antibiotics 612 Acting mainly on gram-negative bacteria 6122 Monobactams D00240 Aztreonam (JP18/USP/INN) Drug groups [BR:br08330] Antibacterial DG01710 beta-Lactam antibiotic DG01454 Monobactam DG00589 Aztreonam D00240 Aztreonam DG01804 Oxyimino beta-lactam DG00589 Aztreonam D00240 Aztreonam Antimicrobials [BR:br08307] Antibacterials Cell wall biosynthesis inhibitor, beta-lactam Monobactam D00240 Aztreonam (JP18/USP/INN) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00240 Aztreonam D00240 Aztreonam for injection Drug groups [BR:br08330] Antibacterial DG01710 beta-Lactam antibiotic DG01454 Monobactam DG00589 Aztreonam DG01804 Oxyimino beta-lactam DG00589 Aztreonam Antimicrobials abbreviations [BR:br08327] Antibacterials Cell wall biosynthesis inhibitor, beta-lactam Monobactam DG00589 Aztreonam | ||||||||||
| Other DBs |
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| KCF data | ATOM 28 1 C2c C 15.4000 -22.4000 2 C5a C 16.6124 -23.1000 3 C8y C 14.1876 -23.1000 4 N1b N 17.8079 -22.4096 5 C1y C 18.9953 -23.0951 6 O5a O 16.6125 -24.4998 7 C8x C 13.0547 -22.3092 8 S2x S 11.9564 -23.1439 9 C8y C 12.4109 -24.4464 10 N5x N 13.7900 -24.4167 11 N1a N 11.6135 -25.5950 #+ 12 N2b N 15.4000 -21.0000 13 O2a O 16.6124 -20.3000 14 C5x C 18.9535 -24.4990 15 N1y N 20.3512 -24.4712 16 C1y C 20.3934 -23.0735 17 S4a S 21.3599 -25.4900 18 O5x O 17.9666 -25.4763 19 C1a C 21.3655 -22.1157 20 O1d O 22.3498 -24.5001 21 O1d O 20.3699 -26.4800 22 O1d O 22.4099 -26.4700 #- 23 C1d C 16.6124 -18.9000 24 C1a C 16.6124 -17.5000 25 C1a C 15.2124 -18.9000 26 C6a C 17.9900 -18.9000 27 O6a O 18.6900 -20.1124 28 O6a O 18.6900 -17.6876 BOND 29 1 1 2 1 2 1 3 1 3 2 4 1 4 5 4 1 #Up 5 2 6 2 6 3 7 2 7 7 8 1 8 8 9 1 9 9 10 2 10 3 10 1 11 9 11 1 12 1 12 2 13 12 13 1 14 5 14 1 15 14 15 1 16 15 16 1 17 5 16 1 18 15 17 1 19 14 18 2 20 16 19 1 #Down 21 17 20 2 22 17 21 2 23 17 22 1 24 13 23 1 25 23 24 1 26 23 25 1 27 23 26 1 28 26 27 2 29 26 28 1 |