| Entry |
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|---|---|---|---|---|---|---|---|---|---|
| Name | Calcitonin salmon (JP18/USP/INN); Salmon calcitonin; Calcimar (TN); Fortical (TN); Miacalcin (TN) | ||||||||
| Product | MIACALCIN (Mylan Institutional LLC), MIACALCIN (Mylan Institutional LLC), MIACALCIN (Mylan Institutional LLC) | ||||||||
| Generic | CALCITONIN SALMON (Apotex Corp.), CALCITONIN SALMON (Leucadia Pharmaceuticals), CALCITONIN SALMON (Par Pharmaceutical), CALCITONIN SALMON (Par Pharmaceutical) | ||||||||
| Formula | C145H240N44O48S2 | ||||||||
| Exact mass | 3429.7133 | ||||||||
| Mol weight | 3431.8531 | ||||||||
| Structure |  | ||||||||
| Simcomp | |||||||||
| Class | Musculo-skeletal system agent DG03232 Osteoporosis agent | ||||||||
| Remark |
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| Efficacy | Antiresorptive, Regulator (calcium) | ||||||||
| Disease | Paget's disease of bone [DS:H00437] Postmenopausal osteoporosis [DS:H01593] | ||||||||
| Target | CALCR [HSA:799] [KO:K04576] | ||||||||
| Pathway |
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| Interaction | |||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS H05 CALCIUM HOMEOSTASIS H05B ANTI-PARATHYROID AGENTS H05BA Calcitonin preparations H05BA01 Calcitonin (salmon synthetic) D00249 Calcitonin salmon (JP18/USP/INN) <US> USP drug classification [BR:br08302] Metabolic Bone Disease Agents Calcium Regulating Hormones Calcitonin, Salmon D00249 Calcitonin salmon (JP18/USP/INN) Drug groups [BR:br08330] Musculo-skeletal system agent DG03232 Osteoporosis agent D00249 Calcitonin salmon Drug classes [BR:br08332] Musculo-skeletal system agent DG03232 Osteoporosis agent D00249 Calcitonin salmon Target-based classification of drugs [BR:br08310] G Protein-coupled receptors Secretin receptor family Calcitonin CALCR D00249 Calcitonin salmon (JP18/USP/INN) <US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00249 Calcitonin salmon | ||||||||
| Other DBs |
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| KCF data | ATOM 239 1 N1y N 31.8310 -21.0514 2 C1y C 32.9628 -21.8642 3 C5a C 31.8310 -19.6624 4 C1x C 30.7195 -21.8642 5 C5a C 34.1152 -21.1132 6 C1x C 32.5203 -23.1918 7 C1c C 30.6374 -18.9626 8 O5a O 33.0452 -18.9626 9 C1x C 31.1312 -23.1918 10 N1b N 35.3395 -21.7717 11 O5a O 34.0329 -19.7343 12 C1b C 30.6580 -17.0899 13 N1b N 29.4334 -19.6624 14 C1c C 36.3995 -21.0824 15 C8y C 29.5670 -16.3800 16 C5a C 28.2192 -18.9626 17 C5a C 37.4695 -21.7100 18 C1b C 36.4302 -19.6418 19 C8x C 28.3529 -17.1003 20 C8x C 29.5569 -14.9599 21 C1c C 27.0050 -19.6624 22 O5a O 28.2398 -17.9027 23 N1b N 37.4695 -23.0578 24 O5a O 38.3853 -21.1544 25 C1b C 35.3395 -19.0348 26 C8x C 27.1184 -16.4006 27 C8x C 28.3120 -14.2706 28 N1b N 25.8320 -18.9626 29 C1c C 27.0154 -21.0514 30 C1c C 36.7596 -23.8605 31 C1b C 35.4013 -17.7795 32 C8y C 27.0978 -14.9910 33 C5a C 24.6178 -19.6624 34 C1a C 25.8320 -21.7410 35 O1a O 28.2192 -21.7410 36 C5a C 36.7492 -26.7827 37 C1c C 35.4118 -23.8811 38 N1b N 34.1358 -17.1311 39 O1a O 25.8732 -14.2811 40 C1c C 23.4036 -18.9626 41 O5a O 24.6178 -21.0514 42 N1b N 35.5660 -27.4825 43 O5a O 37.9634 -27.4825 44 C1a C 35.0576 -24.9100 45 O1a O 34.6914 -22.6565 46 C2c C 34.0842 -15.7214 47 N1b N 22.1895 -19.6624 48 C1b C 23.4036 -17.5736 49 C1c C 34.3519 -26.7932 50 N1a N 35.2676 -14.9498 51 N2a N 32.8082 -15.0733 52 C5a C 21.0063 -18.9626 53 C1b C 22.1895 -16.8637 54 C5a C 33.1377 -27.5132 55 C1b C 34.3414 -25.6303 56 C1c C 19.7921 -19.6624 57 O5a O 21.0063 -17.5736 58 C5a C 22.1895 -15.4848 59 N1b N 31.9235 -26.8239 60 O5a O 33.1583 -28.8820 61 C5a C 32.8599 -25.2600 62 N1b N 18.5881 -18.9626 63 C1b C 19.7921 -21.0514 64 N1a N 21.0063 -14.7749 65 O5a O 23.4036 -14.7749 66 C1c C 30.7400 -27.5237 67 N1a N 32.7157 -23.9797 68 O5a O 31.2342 -24.9822 69 C5a C 17.3844 -19.6624 70 C1c C 21.0063 -21.7410 71 C5a C 29.5259 -26.8341 72 C1c C 30.7505 -28.9228 73 C1c C 16.1702 -18.9626 74 O5a O 17.3844 -21.0514 75 C1a C 21.0063 -23.1196 76 C1a C 22.1895 -21.0514 77 N1b N 28.3221 -27.5338 78 O5a O 29.5157 -25.4450 79 C1a C 29.5569 -29.6124 80 O1a O 31.9748 -29.5814 81 N1b N 14.9766 -19.6624 82 C1b C 16.1702 -17.5736 83 C1b C 27.1285 -26.8445 84 C5a C 13.7830 -18.9626 85 C1b C 14.9766 -16.8637 86 C5a C 25.9248 -27.5338 87 C1c C 12.5688 -19.6624 88 O5a O 13.7830 -17.5736 89 C1b C 14.9766 -15.4848 90 N1b N 24.7106 -26.8651 91 O5a O 25.9350 -28.9539 92 C1b C 12.5688 -21.0514 93 N1b N 11.3752 -18.9626 94 C1b C 13.7830 -14.7749 95 C1c C 23.5272 -27.5750 96 C8y C 13.7830 -21.7410 97 C5a C 10.1611 -19.6624 98 N1a N 13.7830 -13.3960 99 C5a C 22.3029 -26.8752 100 C1b C 23.5272 -28.9539 101 C8x C 15.0384 -21.1851 102 N4x N 13.9167 -23.1196 103 C1c C 8.9776 -18.9626 104 O5a O 10.1611 -21.0514 105 N1b N 21.0988 -27.5854 106 O5a O 22.3029 -25.4862 107 O1a O 22.3234 -29.6638 108 N5x N 15.9643 -22.2244 109 C8x C 15.2851 -23.4079 110 N1b N 7.7634 -19.6624 111 C1b C 8.9776 -17.5736 112 C1b C 19.9052 -26.8958 113 C5a C 6.5493 -18.9626 114 C1c C 10.1611 -16.8637 115 C5a C 18.7015 -27.5854 116 C1c C 6.5493 -17.5736 117 O5a O 5.3351 -19.6624 118 C1a C 10.1405 -15.7832 119 C1a C 11.1282 -17.3471 120 N1b N 17.4873 -26.9063 121 O5a O 18.7116 -28.9846 122 N1b N 5.3351 -16.8637 123 C1b C 7.7634 -16.8637 124 C1c C 16.2833 -27.6060 125 C5a C 5.3351 -15.4848 126 C1b C 7.7121 -15.1658 127 C5a C 15.0795 -26.9164 128 C1c C 16.3039 -29.0052 129 C1c C 4.1519 -14.7749 130 O5a O 6.5493 -14.7749 131 C6a C 8.7822 -14.1677 132 N1y N 13.8549 -27.6367 133 O5a O 15.0795 -25.5274 134 C1a C 15.1001 -29.7049 135 O1a O 17.5079 -29.6948 136 N1b N 4.1519 -13.3960 137 C1b C 2.9479 -15.4848 138 O6a O 8.4530 -12.8198 139 O6a O 9.9862 -14.6203 140 C1y C 12.6924 -26.7932 141 C1x C 13.4023 -28.9846 142 C5a C 2.9479 -12.6963 143 C1b C 2.9479 -16.8637 144 C1x C 11.5501 -27.6367 145 C5a C 12.6924 -25.3833 146 C1x C 11.9926 -28.9846 147 C1c C 2.9479 -11.3072 148 O5a O 1.7546 -13.3960 149 C5a C 4.0182 -18.0057 150 N1a N 14.1371 -24.3934 151 O5a O 11.4782 -24.6734 152 N1b N 4.1519 -10.6179 153 C1b C 1.7546 -10.6179 154 N1a N 3.1538 -19.2404 155 O5a O 5.3043 -18.0367 156 C5a C 4.1519 -9.2286 157 O1a O 1.7546 -9.2286 158 C1c C 5.3351 -8.5187 159 O5a O 2.9479 -8.5187 160 N1b N 6.5493 -9.2286 161 C1b C 5.3351 -7.1297 162 C5a C 7.7634 -8.5187 163 C1c C 4.1519 -6.4505 164 C1c C 7.7634 -7.1297 165 O5a O 8.9776 -9.2286 166 C1a C 2.9479 -7.1297 167 C1a C 4.1519 -5.0615 168 N1b N 8.9776 -6.4505 169 C1b C 6.5493 -6.4505 170 C5a C 10.1611 -7.1297 171 C1b C 6.5493 -5.0615 172 C1b C 11.3752 -6.4505 173 O5a O 10.1611 -8.5187 174 C1b C 5.3351 -4.3412 175 N1b N 12.5688 -7.1297 176 C1b C 5.3351 -2.9727 177 C5a C 13.7830 -6.4505 178 N1a N 4.1519 -2.2834 179 C1c C 14.9766 -7.1297 180 O5a O 13.7830 -5.0615 181 N1b N 16.1702 -6.4505 182 C1b C 14.9766 -8.5187 183 C5a C 17.3844 -7.1297 184 C1c C 13.7830 -9.2286 185 C1c C 18.5881 -6.4505 186 O5a O 17.3844 -8.5187 187 C1a C 13.7830 -10.6179 188 C1a C 12.5688 -8.5187 189 N1b N 19.7921 -7.1297 190 C1c C 18.5881 -5.0615 191 C5a C 21.0063 -6.4505 192 C1a C 19.7921 -4.3412 193 C1a C 17.3844 -4.3412 194 C1c C 22.1895 -7.1297 195 O5a O 21.0063 -5.0615 196 N1b N 23.4036 -6.4505 197 C1b C 22.2205 -10.7928 198 C5a C 24.6178 -7.1297 199 S3a S 23.3317 -11.5027 200 C1c C 25.8320 -6.4505 201 O5a O 24.6178 -8.5187 202 S3a S 24.5355 -10.6487 203 N1b N 27.0154 -7.1297 204 C1c C 25.8320 -5.0615 205 C1b C 25.8114 -11.4409 206 C5a C 28.2192 -6.4505 207 C1a C 24.6178 -4.3412 208 O1a O 27.0154 -4.3412 209 C1c C 26.9537 -10.6487 210 C1c C 29.4334 -7.1297 211 O5a O 28.2192 -5.0615 212 C5a C 28.1884 -11.4409 213 N1a N 26.9226 -9.2698 214 N1b N 30.6374 -6.4505 215 C1b C 29.4540 -8.2719 216 N1b N 29.4951 -10.7412 217 O5a O 28.2090 -12.3671 218 C5a C 31.8310 -7.1297 219 O1a O 28.3323 -8.6217 220 C1c C 30.7195 -11.5439 221 C1c C 33.0452 -6.4505 222 O5a O 31.8310 -8.5187 223 C5a C 31.9029 -10.7928 224 C1b C 30.6580 -13.0051 225 N1b N 34.2593 -7.1297 226 C1b C 33.0452 -5.0615 227 N1b N 33.1890 -11.5027 228 O5a O 31.8310 -9.5067 229 O1a O 31.9235 -13.7768 230 C5a C 34.8356 -9.0743 231 C1c C 34.2593 -4.3412 232 C1c C 34.3414 -10.7928 233 O5a O 36.0599 -9.0743 234 C1a C 34.2593 -2.9727 235 C1a C 35.4529 -5.0615 236 C1b C 35.4118 -11.4821 237 C5a C 36.8584 -10.7412 238 N1a N 37.8154 -11.3792 239 O5a O 36.9202 -9.6299 BOND 243 1 1 2 1 2 1 3 1 3 1 4 1 4 2 5 1 5 2 6 1 6 3 7 1 7 3 8 2 8 4 9 1 9 5 10 1 10 5 11 2 11 7 12 1 12 7 13 1 13 10 14 1 14 12 15 1 15 13 16 1 16 14 17 1 17 14 18 1 18 15 19 1 19 15 20 2 20 16 21 1 21 16 22 2 22 17 23 1 23 17 24 2 24 18 25 1 25 19 26 2 26 20 27 1 27 21 28 1 28 21 29 1 29 23 30 1 30 25 31 1 31 26 32 1 32 28 33 1 33 29 34 1 34 29 35 1 35 30 36 1 36 30 37 1 37 31 38 1 38 32 39 1 39 33 40 1 40 33 41 2 41 36 42 1 42 36 43 2 43 37 44 1 44 37 45 1 45 38 46 1 46 40 47 1 47 40 48 1 48 42 49 1 49 46 50 1 50 46 51 2 51 47 52 1 52 48 53 1 53 49 54 1 54 49 55 1 55 52 56 1 56 52 57 2 57 53 58 1 58 54 59 1 59 54 60 2 60 55 61 1 61 56 62 1 62 56 63 1 63 58 64 1 64 58 65 2 65 59 66 1 66 61 67 1 67 61 68 2 68 62 69 1 69 63 70 1 70 66 71 1 71 66 72 1 72 69 73 1 73 69 74 2 74 70 75 1 75 70 76 1 76 71 77 1 77 71 78 2 78 72 79 1 79 72 80 1 80 73 81 1 81 73 82 1 82 77 83 1 83 81 84 1 84 82 85 1 85 83 86 1 86 84 87 1 87 84 88 2 88 85 89 1 89 86 90 1 90 86 91 2 91 87 92 1 92 87 93 1 93 89 94 1 94 90 95 1 95 92 96 1 96 93 97 1 97 94 98 1 98 95 99 1 99 95 100 1 100 96 101 2 101 96 102 1 102 97 103 1 103 97 104 2 104 99 105 1 105 99 106 2 106 100 107 1 107 101 108 1 108 102 109 1 109 103 110 1 110 103 111 1 111 105 112 1 112 110 113 1 113 111 114 1 114 112 115 1 115 113 116 1 116 113 117 2 117 114 118 1 118 114 119 1 119 115 120 1 120 115 121 2 121 116 122 1 122 116 123 1 123 120 124 1 124 122 125 1 125 123 126 1 126 124 127 1 127 124 128 1 128 125 129 1 129 125 130 2 130 126 131 1 131 127 132 1 132 127 133 2 133 128 134 1 134 128 135 1 135 129 136 1 136 129 137 1 137 131 138 1 138 131 139 2 139 132 140 1 140 132 141 1 141 136 142 1 142 137 143 1 143 140 144 1 144 140 145 1 145 141 146 1 146 142 147 1 147 142 148 2 148 143 149 1 149 145 150 1 150 145 151 2 151 147 152 1 152 147 153 1 153 149 154 1 154 149 155 2 155 152 156 1 156 153 157 1 157 156 158 1 158 156 159 2 159 158 160 1 160 158 161 1 161 160 162 1 162 161 163 1 163 162 164 1 164 162 165 2 165 163 166 1 166 163 167 1 167 164 168 1 168 164 169 1 169 168 170 1 170 169 171 1 171 170 172 1 172 170 173 2 173 171 174 1 174 172 175 1 175 174 176 1 176 175 177 1 177 176 178 1 178 177 179 1 179 177 180 2 180 179 181 1 181 179 182 1 182 181 183 1 183 182 184 1 184 183 185 1 185 183 186 2 186 184 187 1 187 184 188 1 188 185 189 1 189 185 190 1 190 189 191 1 191 190 192 1 192 190 193 1 193 191 194 1 194 191 195 2 195 194 196 1 196 194 197 1 197 196 198 1 198 197 199 1 199 198 200 1 200 198 201 2 201 199 202 1 202 200 203 1 203 200 204 1 204 202 205 1 205 203 206 1 206 204 207 1 207 204 208 1 208 205 209 1 209 206 210 1 210 206 211 2 211 209 212 1 212 209 213 1 213 210 214 1 214 210 215 1 215 212 216 1 216 212 217 2 217 214 218 1 218 215 219 1 219 216 220 1 220 218 221 1 221 218 222 2 222 220 223 1 223 220 224 1 224 221 225 1 225 221 226 1 226 223 227 1 227 223 228 2 228 224 229 1 229 225 230 1 230 226 231 1 231 227 232 1 232 230 233 2 233 231 234 1 234 231 235 1 235 232 236 1 236 236 237 1 237 237 238 1 238 237 239 2 239 6 9 1 240 27 32 2 241 108 109 2 242 144 146 1 243 230 232 1 |