Etidronate disodium


Entry
D00314                      Drug                                   
Name
Etidronate disodium (JP18/USP);
Didronel (TN)
Formula
C2H6O7P2. 2Na
Exact mass
249.9384
Mol weight
249.9919
Structure
Simcomp
Class
Musculo-skeletal system agent
 DG03232  Osteoporosis agent
  DG01600  Bisphosphonate
Remark
Therapeutic category: 3999
ATC code: M05BA01
Chemical structure group: DG00780
Product (DG00780): D00314<JP>
Efficacy
Antiresorptive, Osteoporosis agent
  Disease
Paget's disease of bone [DS:H00437]
Comment
Bisphosphonate
Interaction
Structure map
map07047  Osteoporosis drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M05 DRUGS FOR TREATMENT OF BONE DISEASES
   M05B DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
    M05BA Bisphosphonates
     M05BA01 Etidronic acid
      D00314  Etidronate disodium (JP18/USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   399  Miscellaneous
    3999  Others
     D00314  Etidronate disodium (JP18/USP)
Drug groups [BR:br08330]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   DG01600  Bisphosphonate
    DG00780  Etidronic acid
     D00314  Etidronate disodium
Drug classes [BR:br08332]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   D00314  Etidronate disodium
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00314  Etidronate disodium
  D00314  Etidronate disodium tablets
Drug groups [BR:br08330]
 Musculo-skeletal system agent
  DG03232  Osteoporosis agent
   DG01600  Bisphosphonate
    DG00780  Etidronic acid
Other DBs
CAS: 7414-83-7
PubChem: 7847380
ChEBI: 4906
LigandBox: D00314
NIKKAJI: J31.845K
KCF data

ATOM        13
            1   C1d C    31.3375  -15.6357
            2   P1b P    30.0326  -15.6297
            3   P1b P    32.6071  -15.6357
            4   C1a C    31.3374  -17.0721
            5   O1a O    31.3897  -14.1230
            6   O1c O    30.0326  -17.1309
            7   O1c O    28.5670  -15.5774 #-
            8   O1c O    30.0326  -14.1289
            9   O1c O    32.5953  -17.1309
            10  O1c O    34.0315  -15.6010 #-
            11  O1c O    32.6071  -14.1289
            12  Z   Na   35.3500  -15.5400 #+
            13  Z   Na   26.3900  -15.6100 #+
BOND        10
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     2   7 1
            7     2   8 2
            8     3   9 1
            9     3  10 1
            10    3  11 2