Entry |
|
Name |
Famciclovir (JAN/USP/INN); Famvir (TN) |
Abbr |
FCV |
Product |
|
Generic |
FAMCICLOVIR (ATLANTIC BIOLOGICALS CORP.), FAMCICLOVIR (Apotex Corp.), FAMCICLOVIR (Aurobindo Pharma Limited), FAMCICLOVIR (AvKARE), FAMCICLOVIR (Bryant Ranch Prepack), FAMCICLOVIR (Camber Pharmaceuticals), FAMCICLOVIR (Golden State Medical Supply), FAMCICLOVIR (Macleods Pharmaceuticals Limited), FAMCICLOVIR (PD-Rx Pharmaceuticals), FAMCICLOVIR (Proficient Rx LP), FAMCICLOVIR (Proficient Rx LP), FAMCICLOVIR (Proficient Rx LP), FAMCICLOVIR (Rising Pharmaceuticals), FAMCICLOVIR (Teva Pharmaceuticals USA) |
Formula |
C14H19N5O4
|
Exact mass |
321.1437
|
Mol weight |
321.3318
|
Structure |
|
Class |
Antiviral
DG02840 Anti-herpesvirus agent
|
Remark |
Therapeutic category: | 6250 |
ATC code: | J05AB09 S01AD07 |
|
Efficacy |
Antiviral, DNA polymerase inhibitor |
Disease |
Herpes labialis, Genital herpes [DS:H00365] Herpes zoster [DS:H00366] |
Comment |
Active form of prodrug: Penciclovir [DR:D05407]
|
Target |
Herpesvirus DNA polymerase [KO:K18964] |
Pathway |
ko03240 | Viral replication |
|
Interaction |
|
Structure map |
map07044 | Antiviral agents |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB09 Famciclovir
D00317 Famciclovir (JAN/USP/INN) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AD Antivirals
S01AD07 Famciclovir
D00317 Famciclovir (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Antivirals
Antiherpetic Agents
Famciclovir
D00317 Famciclovir (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
625 Antivirals
6250 Antivirals
D00317 Famciclovir (JAN/USP/INN)
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
D00317 Famciclovir
Drug classes [BR:br08332]
Antiviral
DG02840 Anti-herpesvirus agent
D00317 Famciclovir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00317 Famciclovir (JAN/USP/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00317 Famciclovir (JAN/USP/INN)
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D00317
Prodrugs [br08324.html]
D00317
|
Other DBs |
|
KCF data |
ATOM 23
1 C8y C 21.2800 -21.7700
2 C8y C 21.2800 -20.3700
3 N4y N 19.8800 -22.1900
4 N5x N 22.4700 -22.5400
5 N5x N 19.9500 -19.9500
6 C8x C 22.4700 -19.7400
7 C8x C 19.1100 -21.0700
8 C8y C 23.7300 -21.8400
9 N5x N 23.7300 -20.4400
10 N1a N 24.8500 -22.6100
11 C1b C 19.8800 -23.5900
12 C1b C 18.6900 -24.2900
13 C1c C 17.5000 -23.5900
14 C1b C 16.3100 -24.2900
15 C1b C 17.5000 -22.1900
16 O7a O 16.3100 -21.4900
17 O7a O 15.1200 -23.5900
18 C7a C 13.8600 -24.2900
19 C1a C 12.7400 -23.5900
20 O6a O 13.8600 -25.6900
21 C7a C 16.3214 -20.0900
22 O6a O 17.5308 -19.4048
23 C1a C 15.1062 -19.3752
BOND 24
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 2
8 6 9 2
9 8 10 1
10 5 7 2
11 8 9 1
12 3 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 13 15 1
17 15 16 1
18 14 17 1
19 17 18 1
20 18 19 1
21 18 20 2
22 16 21 1
23 21 22 2
24 21 23 1
|