Entry |
|
Name |
Idoxuridine (JP18/USP/INN); Dendrid (TN); Herplex (TN) |
Abbr |
IDU |
Formula |
C9H11IN2O5
|
Exact mass |
353.9713
|
Mol weight |
354.0985
|
Structure |
|
Simcomp |
|
Class |
Antiviral
DG02840 Anti-herpesvirus agent
|
Remark |
ATC code: | D06BB01 J05AB02 S01AD01 |
|
Efficacy |
Antiviral, DNA polymerase inhibitor |
Target |
Herpesvirus DNA polymerase [KO:K18964] |
Pathway |
ko03240 | Viral replication |
|
Structure map |
map07044 | Antiviral agents |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
D06BB Antivirals
D06BB01 Idoxuridine
D00342 Idoxuridine (JP18/USP/INN)
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB02 Idoxuridine
D00342 Idoxuridine (JP18/USP/INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AD Antivirals
S01AD01 Idoxuridine
D00342 Idoxuridine (JP18/USP/INN)
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
D00342 Idoxuridine
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00342 Idoxuridine (JP18/USP/INN)
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00342 Idoxuridine (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00342 Idoxuridine
D00342 Idoxuridine ophthalmic solution
|
Other DBs |
|
KCF data |
ATOM 17
1 C1y C 20.7200 -17.2900
2 O2x O 19.6000 -16.4500
3 C1x C 20.3000 -18.6200
4 C1y C 18.4800 -17.2900
5 C1y C 18.9000 -18.6200
6 C1b C 17.2900 -16.4500
7 O1a O 18.1300 -19.7400
8 O1a O 15.9600 -17.0800
9 C8x C 21.9100 -15.1900
10 N4y N 21.9100 -16.5900
11 C8y C 23.1000 -17.2900
12 N4x N 24.3600 -16.5900
13 C8y C 24.3600 -15.1900
14 C8y C 23.1000 -14.4900
15 X I 23.1000 -13.0900
16 O5x O 25.5500 -14.4900
17 O5x O 23.1000 -18.6900
BOND 18
1 1 2 1
2 1 3 1
3 2 4 1
4 3 5 1
5 4 6 1 #Up
6 5 7 1 #Down
7 6 8 1
8 4 5 1
9 9 10 1
10 10 11 1
11 11 12 1
12 12 13 1
13 13 14 1
14 9 14 2
15 14 15 1
16 13 16 2
17 11 17 2
18 1 10 1 #Up
|