| Entry |
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| Name | Metronidazole (JP18/USP/INN); Flagyl (TN); Noritate (TN); Nuvessa (TN); Vandazole (TN) | ||||||||||||
| Product | METRONIDAZOLE (B. Braun Medical), NORITATE (Bausch Health US), METRONIDAZOLE (Baxter Healthcare Corporation), METRONIDAZOLE (Baxter Healthcare Corporation), NUVESSA (Exeltis USA), METROCREAM (Galderma Laboratories), METROGEL (Galderma Laboratories), METROLOTION (Galderma Laboratories), METRONIDAZOLE (General Injectables and Vaccines), METRONIDAZOLE (Henry Schein), METRONIDAZOLE (Hospira), FLAGYL (Pfizer Laboratories Div Pfizer), VANDAZOLE (RPK Pharmaceuticals), VANDAZOLE (Upsher-Smith Laboratories) | ||||||||||||
| Generic | METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE VAGINAL (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (A-S Medication Solutions), METRONIDAZOLE (AMICI PHARMACEUTICALS LLC), METRONIDAZOLE (AMICI PHARMACEUTICALS LLC), METRONIDAZOLE (Alembic Labs LLC), METRONIDAZOLE (Alembic Pharmaceuticals), METRONIDAZOLE (Alembic Pharmaceuticals), METRONIDAZOLE (Alembic Pharmaceuticals Limited), METRONIDAZOLE (Alembic Pharmaceuticals Limited), METRONIDAZOLE (Alembic Pharmaceuticals Limited), METRONIDAZOLE (Alembic Pharmaceuticals), METRONIDAZOLE (Aleor Dermaceuticals Limited), METRONIDAZOLE (American Health Packaging), METRONIDAZOLE (Amneal Pharmaceuticals of New York LLC), METRONIDAZOLE (Aurobindo Pharma Limited), METRONIDAZOLE (AvPAK), METRONIDAZOLE (Baxter Healthcare Corporation), METRONIDAZOLE (BluePoint Laboratories), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE VAGINAL (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Bryant Ranch Prepack), METRONIDAZOLE (Cadila Pharmaceuticals Limited), METRONIDAZOLE500 MG (Cambridge Therapeutics Technologies), METRONIDAZOLE250 MG (Cambridge Therapeutics Technologies), METRONIDAZOLE (Cardinal Health), METRONIDAZOLE (Cardinal Health), METRONIDAZOLE (Clinical Solutions Wholesale), METRONIDAZOLE (Cosette Pharmaceuticals), METRONIDAZOLE (Cosette Pharmaceuticals), METRONIDAZOLE (Cosette Pharmaceuticals), METRONIDAZOLE (Cronus Pharma LLC), METRONIDAZOLE (DIRECT RX), METRONIDAZOLE (DIRECT RX), METRONIDAZOLE (Denton Pharma), METRONIDAZOLE (Denton Pharma), METRONIDAZOLE (Denton Pharma), METRONIDAZOLE (Denton Pharma), METRONIDAZOLE (Denton Pharma), METRONIDAZOLE (Denton Pharma), METRONIDAZOLE (Direct Rx), METRONIDAZOLE (Direct_Rx), METRONIDAZOLE (Direct_Rx), METRONIDAZOLE (Fougera Pharmaceuticals), METRONIDAZOLE (Fougera Pharmaceuticals), METRONIDAZOLE (Fougera Pharmaceuticals), METRONIDAZOLE (GLENMARK PHARMACEUTICALS), METRONIDAZOLE (Gland Pharma Limited), METRONIDAZOLE (Golden State Medical Supply), METRONIDAZOLE (Golden State Medical Supply), METRONIDAZOLE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), METRONIDAZOLE (Hospira), METRONIDAZOLE (Lake Erie Medical DBA Quality Care Products LLC), METRONIDAZOLE (Major Pharmaceuticals), METRONIDAZOLE (Major Pharmaceuticals), ROSADAN (Medimetriks Pharmaceuticals), ROSADAN (Medimetriks Pharmaceuticals), METRONIDAZOLE (Northstar Rx LLC), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (NuCare Pharmaceuticals), METRONIDAZOLE (Oceanside Pharmaceuticals), METRONIDAZOLE (PD-Rx Pharmaceuticals), METRONIDAZOLE (PD-Rx Pharmaceuticals), METRONIDAZOLE (PD-Rx Pharmaceuticals), METRONIDAZOLE (PD-Rx Pharmaceuticals), METRONIDAZOLE (PD-Rx Pharmaceuticals), METRONIDAZOLE (PD-Rx Pharmaceuticals), METRONIDAZOLE VAGINAL (Padagis Israel Pharmaceuticals), METRONIDAZOLE (PharmPak), METRONIDAZOLE (PharmPak), METRONIDAZOLE TOPICAL GEL (Prasco Laboratories), METRONIDAZOLE (Prasco Laboratories), METRONIDAZOLE (Prasco Laboratories), METRONIDAZOLE (Prasco Laboratories), METRONIDAZOLE (Preferred Pharmaceuticals), METRONIDAZOLE (Preferred Pharmaceuticals), METRONIDAZOLE (Preferred Pharmaceuticals), METRONIDAZOLE (Preferred Pharmaceuticals), METRONIDAZOLE (Preferred Pharmaceutiicals), METRONIDAZOLE (Proficient Rx LP), METRONIDAZOLE (Proficient Rx LP), METRONIDAZOLE (Proficient Rx LP), METRONIDAZOLE (Quality Care Products), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE VAGINAL (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (REMEDYREPACK), METRONIDAZOLE (RPK Pharmaceuticals), METRONIDAZOLE (RPK Pharmaceuticals), METRONIDAZOLE (RPK Pharmaceuticals), METRONIDAZOLE (RPK Pharmaceuticals), METRONIDAZOLE (RedPharm Drug), METRONIDAZOLE (RedPharm Drug), METRONIDAZOLE (RedPharm Drug), METRONIDAZOLE (RedPharm Drug), METRONIDAZOLE (RedPharm Drug), METRONIDAZOLE (Rising Pharma Holdings), METRONIDAZOLE (Rising Pharmaceuticals), METRONIDAZOLE (ST. MARY'S MEDICAL PARK PHARMACY), METRONIDAZOLE (Sagent Pharmaceuticals), METRONIDAZOLE (Sandoz), METRONIDAZOLE (Sandoz), METRONIDAZOLE (Solaris Pharma Corporation), METRONIDAZOLE (St. Mary's Medical Park Pharmacy), METRONIDAZOLE (St. Mary's Medical Park Pharmacy), METRONIDAZOLE (Strides Pharma Science Limited), METRONIDAZOLE (Sun Pharmaceutical Industries), METRONIDAZOLE (Taro Pharmaceuticals U.S.A.), METRONIDAZOLE (Taro Pharmaceuticals U.S.A.), METRONIDAZOLE (Taro Pharmaceuticals U.S.A.), METRONIDAZOLE (Teva Pharmaceuticals USA), METRONIDAZOLE (Unichem Pharmaceuticals (USA)), METRONIDAZOLE (Viona Pharmaceuticals), METRONIDAZOLE (medsource pharmaceuticals), METRONIDAZOLE TOPICAL CREAM (DirectRx) | ||||||||||||
| Formula | C6H9N3O3 | ||||||||||||
| Exact mass | 171.0644 | ||||||||||||
| Mol weight | 171.154 | ||||||||||||
| Structure |  | ||||||||||||
| Simcomp | |||||||||||||
| Class | Antiparasitic DG01884 Imidazole antiprotozoal Metabolizing enzyme substrate DG01638 CYP2A6 substrate Metabolizing enzyme inhibitor DG01643 CYP2C9 inhibitor | ||||||||||||
| Remark |
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| Efficacy | Antibacterial, Antiprotozoal, DNA synthesis inhibitor | ||||||||||||
| Disease | Bacterial vaginosis [DS:H01380] Trichomoniasis [DS:H00812] Intestinal amebiasis; amebic dysentery [DS:H00360] Bacterial endocarditis [DS:H00334] Anaerobic bacterial infections [DS:H01410] | ||||||||||||
| Comment | Nitroimidazole derivative | ||||||||||||
| Target | DNA | ||||||||||||
| Metabolism | Enzyme: CYP2A6 [HSA:1548] | ||||||||||||
| Interaction | CYP inhibition: CYP2C9 [HSA:1559] | ||||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] A ALIMENTARY TRACT AND METABOLISM A01 STOMATOLOGICAL PREPARATIONS A01A STOMATOLOGICAL PREPARATIONS A01AB Antiinfectives and antiseptics for local oral treatment A01AB17 Metronidazole D00409 Metronidazole (JP18/USP/INN) <JP/US> D DERMATOLOGICALS D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE D06B CHEMOTHERAPEUTICS FOR TOPICAL USE D06BX Other chemotherapeutics D06BX01 Metronidazole D00409 Metronidazole (JP18/USP/INN) <JP/US> G GENITO URINARY SYSTEM AND SEX HORMONES G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS G01AF Imidazole derivatives G01AF01 Metronidazole D00409 Metronidazole (JP18/USP/INN) <JP/US> J ANTIINFECTIVES FOR SYSTEMIC USE J01 ANTIBACTERIALS FOR SYSTEMIC USE J01X OTHER ANTIBACTERIALS J01XD Imidazole derivatives J01XD01 Metronidazole D00409 Metronidazole (JP18/USP/INN) <JP/US> P ANTIPARASITIC PRODUCTS, INSECTICIDES AND REPELLENTS P01 ANTIPROTOZOALS P01A AGENTS AGAINST AMOEBIASIS AND OTHER PROTOZOAL DISEASES P01AB Nitroimidazole derivatives P01AB01 Metronidazole D00409 Metronidazole (JP18/USP/INN) <JP/US> USP drug classification [BR:br08302] Antibacterials Antibacterials, Other Metronidazole D00409 Metronidazole (JP18/USP/INN) Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 25 Urogenital and anal organ agents 252 Genital organ agents 2529 Others D00409 Metronidazole (JP18/USP/INN) 26 Epidermides 269 Miscellaneous 2699 Others D00409 Metronidazole (JP18/USP/INN) 6 Agents against pathologic organisms and parasites 64 Parasitics (systemic) 641 Antiprotozoans 6419 Others D00409 Metronidazole (JP18/USP/INN) Drug groups [BR:br08330] Antiparasitic DG01884 Imidazole antiprotozoal DG00006 Metronidazole D00409 Metronidazole Metabolizing enzyme substrate DG01638 CYP2A6 substrate DG00006 Metronidazole D00409 Metronidazole Metabolizing enzyme inhibitor DG01643 CYP2C9 inhibitor DG00006 Metronidazole D00409 Metronidazole Antimicrobials [BR:br08307] Antibacterials Bactericidal action Imidazole D00409 Metronidazole (JP18/USP/INN) <JP/US> Antiparasitics Agents against Amebiasis and other antiprotozoals Nitroimidazole derivatives D00409 Metronidazole (JP18/USP/INN) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00409 Metronidazole D00409 Metronidazole tablets Drug metabolizing enzymes and transporters [br08309.html] Drug metabolizing enzymes D00409 Drug groups [BR:br08330] Antiparasitic DG01884 Imidazole antiprotozoal DG00006 Metronidazole Metabolizing enzyme substrate DG01638 CYP2A6 substrate DG00006 Metronidazole Metabolizing enzyme inhibitor DG01643 CYP2C9 inhibitor DG00006 Metronidazole Antimicrobials abbreviations [BR:br08327] Antibacterials Bactericidal action Imidazole DG00006 Metronidazole | ||||||||||||
| Other DBs |
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| KCF data | ATOM 12 1 N4y N 22.2483 -16.2228 2 C8y C 21.8345 -17.4879 3 C8y C 21.1640 -15.4301 4 C1b C 23.3153 -15.5992 5 C8x C 20.5053 -17.4879 6 N2b N 22.6157 -18.5665 #+ 7 N5x N 20.0855 -16.2228 8 C1a C 21.1640 -14.1009 9 C1b C 24.3995 -16.2812 10 O3a O 23.7875 -19.7150 11 O3a O 21.1582 -19.7207 #- 12 O1a O 25.6763 -15.5992 BOND 12 1 1 2 1 2 1 3 1 3 1 4 1 4 2 5 2 5 2 6 1 6 3 7 2 7 3 8 1 8 4 9 1 9 6 10 2 10 6 11 1 11 9 12 1 12 5 7 1 |