| Entry |
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| Name | Misoprostol (JAN/USP/INN); Cytotec (TN) | ||||||||||
| Product | CYTOTEC (Pfizer Laboratories Div Pfizer) | ||||||||||
| Generic | MISOPROSTOL (American Health Packaging), MISOPROSTOL (Bryant Ranch Prepack), MISOPROSTOL (Bryant Ranch Prepack), MISOPROSTOL (Cadila Healthcare Limited), MISOPROSTOL (GenBioPro), MISOPROSTOL (GenBioPro), MISOPROSTOL (Greenstone LLC), MISOPROSTOL (Lupin Pharmaceuticals), MISOPROSTOL (Marlex Pharmaceuticals), MISOPROSTOL (Novel Laboratories), MISOPROSTOL (Novitium Pharma LLC), MISOPROSTOL (NuCare Pharmaceuticals), MISOPROSTOL (PD-Rx Pharmaceuticals), MISOPROSTOL (PD-Rx Pharmaceuticals), MISOPROSTOL (PD-Rx Pharmaceuticals), MISOPROSTOL (PD-Rx Pharmaceuticals), MISOPROSTOL (PharmPak), MISOPROSTOL (Pharmacist Pharmaceutical), MISOPROSTOL (Zydus Pharmaceuticals (USA)) | ||||||||||
| Formula | C22H38O5 | ||||||||||
| Exact mass | 382.2719 | ||||||||||
| Mol weight | 382.5341 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Hormonal agent DG01961 Prostaglandin derivative DG01611 Prostaglandin E1 derivative Gastrointestinal agent DG01975 Agents for peptic ulcer | ||||||||||
| Remark |
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| Efficacy | Anti-ulcerative, Prostaglandin E receptor agonist | ||||||||||
| Disease | Gastric ulcers [DS:H01634] | ||||||||||
| Comment | Prostaglandin E1 analog | ||||||||||
| Target | PTGER2 [HSA:5732] [KO:K04259] PTGER3 [HSA:5733] [KO:K04260] PTGER4 [HSA:5734] [KO:K04261] | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] A ALIMENTARY TRACT AND METABOLISM A02 DRUGS FOR ACID RELATED DISORDERS A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) A02BB Prostaglandins A02BB01 Misoprostol D00419 Misoprostol (JAN/USP/INN) <JP/US> G GENITO URINARY SYSTEM AND SEX HORMONES G02 OTHER GYNECOLOGICALS G02A UTEROTONICS G02AD Prostaglandins G02AD06 Misoprostol D00419 Misoprostol (JAN/USP/INN) <JP/US> USP drug classification [BR:br08302] Gastrointestinal Agents Protectants Misoprostol D00419 Misoprostol (JAN/USP/INN) Hormonal Agents, Stimulant/Replacement/Modifying (Prostaglandins) Misoprostol D00419 Misoprostol (JAN/USP/INN) Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 23 Digestive organ agents 232 Peptic ulcer agents 2329 Others D00419 Misoprostol (JAN/USP/INN) Drug groups [BR:br08330] Hormonal agent DG01961 Prostaglandin derivative DG01611 Prostaglandin E1 derivative D00419 Misoprostol Gastrointestinal agent DG01975 Agents for peptic ulcer D00419 Misoprostol Target-based classification of drugs [BR:br08310] G Protein-coupled receptors Rhodopsin family Prostaglandin PTGER2 D00419 Misoprostol (JAN/USP/INN) <JP/US> PTGER3 D00419 Misoprostol (JAN/USP/INN) <JP/US> PTGER4 D00419 Misoprostol (JAN/USP/INN) <JP/US> | ||||||||||
| Other DBs |
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| KCF data | ATOM 27 1 C1y C 20.0900 -21.8400 2 C1y C 20.0900 -23.2400 3 C5x C 18.7600 -21.4200 4 C1b C 21.3500 -20.7900 5 C1y C 18.7600 -23.7300 6 C2b C 21.3500 -24.2900 7 C1x C 17.9900 -22.6100 8 O5x O 18.3400 -20.1600 9 O1a O 18.3400 -24.9900 10 C2b C 22.5400 -23.5900 11 C1b C 23.7300 -24.2900 12 C1d C 24.9200 -23.5900 13 C1b C 26.0400 -24.2900 14 C1b C 27.3000 -23.5900 15 C1b C 28.4900 -24.2900 16 C1a C 29.6800 -23.5900 17 C1b C 22.5400 -21.4900 18 C1b C 23.7300 -20.7900 19 C1b C 24.9200 -21.4900 20 C1b C 26.0400 -20.7900 21 C1b C 27.2300 -21.4900 22 C7a C 28.4200 -20.7900 23 O7a O 29.6800 -21.4900 24 O1a O 25.8300 -22.6100 25 C1a C 23.9400 -22.6100 26 C1a C 30.8807 -20.7701 27 O6a O 28.4028 -19.3901 BOND 27 1 1 2 1 2 1 3 1 3 1 4 1 #Down 4 2 5 1 5 2 6 1 #Up 6 3 7 1 7 3 8 2 8 5 9 1 #Down 9 6 10 2 10 10 11 1 11 11 12 1 12 12 13 1 13 13 14 1 14 14 15 1 15 15 16 1 16 5 7 1 17 4 17 1 18 17 18 1 19 18 19 1 20 19 20 1 21 20 21 1 22 21 22 1 23 22 23 1 24 12 24 1 25 12 25 1 26 23 26 1 27 22 27 2 |