Entry

D00439                      Drug

Name

Nitrofurantoin (JAN/USP/INN);
Furadantin (TN);
Macrobid (TN)

Abbr

NIT

Product

NITROFURANTION MACROCRYSTALS (Lake Erie Medical DBA Quality Care Products LLC), NITROFURANTION MACROCRYSTALS (Proficient Rx LP), NITROFURANTION MACROCRYSTALS (Proficient Rx LP), FURADANTIN (Casper Pharma LLC), NITROFURANTOIN MACROCRYSTALS (DIRECT RX), MACRODANTIN (Almatica Pharma LLC), NITROFURANTOIN MACROCRYSTALS (Alvogen), NITROFURANTION MACROCRYSTALS (Bryant Ranch Prepack), NITROFURANTOIN MACROCRYSTALS (Bryant Ranch Prepack), NITROFURANTOIN MACROCRYSTALS (Major Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (PD-Rx Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Preferred Pharmaceuticals), NITROFURANTOIN MONOHYDRATE MACROCRYSTALLINE (DIRECT RX), NITROFURANTOIN MONOHYDRATE MACROCRYSTALLINE (Direct_Rx), NITROFURANTOIN MONO (PharmPak), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (A-S Medication Solutions), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (A-S Medication Solutions), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (A-S Medication Solutions), MACROBID (Almatica Pharma LLC), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Alvogen), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Bryant Ranch Prepack), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Bryant Ranch Prepack), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Denton Pharma), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (NuCare Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (NuCare Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (PD-Rx Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (PD-Rx Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (Proficient Rx LP), MACROBID (REMEDYREPACK), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (REMEDYREPACK), NITROFURANTOIN MONOHYDRATE/ MACROCRYSTALLINE (RPK Pharmaceuticals)

Generic

NITROFURANTION (A-S Medication Solutions), NITROFURANTION (BluePoint Labortories), NITROFURANTION (Bryant Ranch Prepack), NITROFURANTION (Bryant Ranch Prepack), NITROFURANTION (DIRECT RX), NITROFURANTION (NuCare Pharmaceuticals), NITROFURANTION (NuCare Pharmaceuticals), NITROFURANTION (Proficient Rx LP), NITROFURANTION (Quality Care Products), NITROFURANTION (REMEDYREPACK), NITROFURANTION (Sun Pharmaceutical Industries), NITROFURANTOIN (Actavis Pharma), NITROFURANTOIN (Actavis Pharma), NITROFURANTOIN (Alembic Pharmaceuticals), NITROFURANTOIN (Alembic Pharmaceuticals Limited), NITROFURANTOIN (American Health Packaging), NITROFURANTOIN (Amneal Pharmaceuticals LLC), NITROFURANTOIN (Amneal Pharmaceuticals of New York LLC), NITROFURANTOIN (BluePoint Laboratories), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Directrx), NITROFURANTOIN (Lupin Pharmaceuticals), NITROFURANTOIN (Nostrum Laboratories), NITROFURANTOIN (Novel Laboratories), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN (Proficient Rx LP), NITROFURANTOIN (Proficient Rx LP), NITROFURANTOIN (Rising Pharma Holdings), NITROFURANTOIN (Trigen Laboratories), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (American Health Packaging), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Asclemed USA), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Bryant Ranch Prepack), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Bryant Ranch Prepack), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Eon Labs), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Jubilant Cadista Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Northstar RxLLC), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NuCare Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NuCare Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (NuCare Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (PD-Rx Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (PD-Rx Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Preferred Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Proficient Rx LP), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Proficient Rx LP), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (Quality Care Products), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (REMEDYREPACK), NITROFURANTOIN (RPK Pharmaceuticals), NITROFURANTOIN (MONOHYDRATE/MACROCRYSTALS) (St. Mary's Medical Park Pharmacy), NITROFURANTOIN MACROCRYSTALS (Amneal Pharmaceuticals of New York LLC), NITROFURANTOIN MACROCRYSTALS (AvPAK), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN MACROCRYSTALS (Cadila Healthcare Limited), NITROFURANTOIN MACROCRYSTALS (Lupin Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Major Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Novel Laboratories), NITROFURANTOIN MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN MACROCRYSTALS (Proficient Rx LP), NITROFURANTOIN MACROCRYSTALS (REMEDYREPACK), NITROFURANTOIN MACROCRYSTALS (Zydus Pharmaceuticals (USA)), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (A-S Medication Solutions), NITROFURANTOIN (American Health Packaging), NITROFURANTOIN (Amneal Pharmaceuticals LLC), NITROFURANTOIN (AvKARE), NITROFURANTOIN (AvPAK), NITROFURANTOIN (Bryant Ranch Prepack), NITROFURANTOIN (Denton Pharma), NITROFURANTOIN (NuCare Pharmaceuticals), NITROFURANTOIN MONOHYDRATE/MACROCRYSTALS (NuCare Pharmaceuticals), NITROFURANTOIN (Quality Care Products), NITROFURANTOIN (RPK Pharmaceuticals), NITROFURANTOIN (RedPharm Drug), NITROFURANTOIN (St. Mary's Medical Park Pharmacy)

Formula

C8H6N4O5

Exact mass

238.0338

Mol weight

238.157

Structure

Simcomp

Class

Antibacterial
DG01553 5-Nitrofuran antibacterial
DG01552 Hydantoin type nitrofuran

Remark

Same as:

C07268

ATC code:

J01XE01

Product:

D00439<US>

Efficacy

Antibacterial

Disease

Uncomplicated urinary tract infection [DS:H01176]

Interaction

Other map

map04976

Bile secretion

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01X OTHER ANTIBACTERIALS
    J01XE Nitrofuran derivatives
     J01XE01 Nitrofurantoin
      D00439  Nitrofurantoin (JAN/USP/INN) <US>
USP drug classification [BR:br08302]
Antibacterials
  Antibacterials, Other
   Nitrofurantoin
    D00439  Nitrofurantoin (JAN/USP/INN)
Drug groups [BR:br08330]
Antibacterial
  DG01553  5-Nitrofuran antibacterial
   DG01552  Hydantoin type nitrofuran
    D00439  Nitrofurantoin
Antimicrobials [BR:br08307]
Antibacterials
  Bactericidal action
   Hydantoin type nitrofuran
    D00439  Nitrofurantoin (JAN/USP/INN) <US>
Antimicrobials abbreviations [BR:br08327]
Antibacterials
  Bactericidal action
   Hydantoin type nitrofuran
    D00439  Nitrofurantoin (JAN/USP/INN)
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
  D00439

Other DBs

CAS:

67-20-9

PubChem:

7847505

ChEBI:

71415

PDB-CCD:

U6Z[PDBj]

LigandBox:

D00439

NIKKAJI:

J1.410I

KCF data

ATOM        17
            1   N1x N    23.7300  -16.2400
            2   C5x C    23.3100  -14.9800
            3   C1x C    21.9800  -14.9800
            4   N1y N    21.5600  -16.2400
            5   C5x C    22.6100  -17.0800
            6   O5x O    22.6100  -18.4800
            7   O5x O    24.0800  -13.8600
            8   N2b N    20.3700  -16.9400
            9   C2b C    19.1800  -16.2400
            10  C8y C    17.9900  -16.9400
            11  O2x O    16.8700  -16.1000
            12  C8y C    15.7500  -16.9400
            13  C8x C    16.1700  -18.2700
            14  C8x C    17.5700  -18.2700
            15  N2b N    14.6300  -16.2400 #+
            16  O3a O    13.1600  -17.2200 #-
            17  O3a O    14.6300  -14.9100
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     5   6 2
            7     2   7 2
            8     8   9 2
            9     8   4 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 2
            14   13  14 1
            15   10  14 2
            16   12  15 1
            17   15  16 1
            18   15  17 2