| Entry |
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| Name | Omeprazole (JP18/USP/INN); Prilosec (TN) | ||||||||||||
| Product | |||||||||||||
| Generic | OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (Advanced Rx Pharmacy of Tennessee), OMEPRAZOLE (Advanced Rx Pharmacy of Tennessee), OMEPRAZOLE (Advanced Rx Pharmacy of Tennessee), OMEPRAZOLE (Advanced Rx Pharmacy of Tennessee), OMEPRAZOLE (American Health Packaging), OMEPRAZOLE (American Health Packaging), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Apotex Corp), OMEPRAZOLE (Asclemed USA), OMEPRAZOLE (Aurobindo Pharma Limited), OMEPRAZOLE (AvPAK), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Cadila Healthcare Limited), OMEPRAZOLE (Camber Pharmaceuticals), OMEPRAZOLE (Cardinal Health), OMEPRAZOLE (Cardinal Health 107), OMEPRAZOLE (Clinical Solutions Wholesale), OMEPRAZOLE (Denton Pharma), OMEPRAZOLE (DirexctRX), OMEPRAZOLE (Dr. Reddy's Laboratories Limited), OMEPRAZOLE (Dr. Reddy's Laboratories Limited), OMEPRAZOLE (Glenmark Pharmaceuticals), OMEPRAZOLE (Golden State Medical Supply), OMEPRAZOLE (Golden State Medical Supply), OMEPRAZOLE (Golden State Medical Supply), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lannett Company), OMEPRAZOLE (Major Pharmaceuticals), OMEPRAZOLE (Major Pharmaceuticals), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (NorthStar Rx LLC), OMEPRAZOLE (NorthStar Rx LLC), OMEPRAZOLE (Northwind Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCarePharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaeuticals), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (QPharma), OMEPRAZOLE (Quality Care Products), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (RPK Pharmaceuticals), OMEPRAZOLE (RPK Pharmaceuticals), OMEPRAZOLE (RedPharm Drug), OMEPRAZOLE (RedPharm Drug), OMEPRAZOLE (RedPharm Drug), OMEPRAZOLE (Rising Health), OMEPRAZOLE (Sandoz), OMEPRAZOLE (Sandoz), OMEPRAZOLE (Sandoz), OMEPRAZOLE (St. Mary's Medical Park Pharmacy), OMEPRAZOLE (St. Mary's Medical Park Pharmacy), OMEPRAZOLE (St. Mary's Medical Park Pharmacy), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Xiromed), OMEPRAZOLE (Zydus Pharmaceuticals (USA)), OMEPRAZOLE (medsource pharmaceuticals), OMEPRAZOLE DR (Direct Rx) | ||||||||||||
| Formula | C17H19N3O3S | ||||||||||||
| Exact mass | 345.1147 | ||||||||||||
| Mol weight | 345.4161 | ||||||||||||
| Structure |  | ||||||||||||
| Simcomp | |||||||||||||
| Class | Gastrointestinal agent DG01975 Agents for peptic ulcer DG01646 Proton pump inhibitor (PPI) Metabolizing enzyme substrate DG01639 CYP2C19 substrate DG01633 CYP3A/CYP3A4 substrate DG02913 CYP3A4 substrate | ||||||||||||
| Remark |
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| Efficacy | Antisecretory (gastric acid), Anti-ulcerative, Proton pump inhibitor | ||||||||||||
| Disease | Duodenal ulcer [DS:H01634] Gastric ulcer [DS:H01634] Gastroesophageal reflux disease [DS:H01602] Zollinger-Ellison syndrome [DS:H01522] Multiple endocrine adenomas [DS:H01102] | ||||||||||||
| Comment | Benzimidazole derivative | ||||||||||||
| Target | ATP4 [HSA:495 496] [KO:K01542 K01543] | ||||||||||||
| Pathway |
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| Metabolism | Enzyme: CYP2C19 [HSA:1557]; CYP3A4 [HSA:1576] | ||||||||||||
| Interaction | |||||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] A ALIMENTARY TRACT AND METABOLISM A02 DRUGS FOR ACID RELATED DISORDERS A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) A02BC Proton pump inhibitors A02BC01 Omeprazole D00455 Omeprazole (JP18/USP/INN) <JP/US> USP drug classification [BR:br08302] Gastrointestinal Agents Proton Pump Inhibitors Omeprazole D00455 Omeprazole (JP18/USP/INN) Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 23 Digestive organ agents 232 Peptic ulcer agents 2329 Others D00455 Omeprazole (JP18/USP/INN) Drug groups [BR:br08330] Gastrointestinal agent DG01975 Agents for peptic ulcer DG01646 Proton pump inhibitor (PPI) DG00020 Omeprazole D00455 Omeprazole Metabolizing enzyme substrate DG01639 CYP2C19 substrate DG00020 Omeprazole D00455 Omeprazole DG01633 CYP3A/CYP3A4 substrate DG02913 CYP3A4 substrate DG00020 Omeprazole D00455 Omeprazole Drug classes [BR:br08332] Gastrointestinal agent DG01646 Proton pump inhibitor (PPI) D00455 Omeprazole Target-based classification of drugs [BR:br08310] Enzymes Hydrolases (EC3) ATPase ATP4 D00455 Omeprazole (JP18/USP/INN) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00455 Omeprazole D00455 Omeprazole enteric-coated tablets Drug metabolizing enzymes and transporters [br08309.html] Drug metabolizing enzymes D00455 Pharmacogenomic biomarkers [br08341.html] Polymorphisms and mutations affecting drug response D00455 Rx-to-OTC switch list in the USA [br08315.html] D00455 Drug groups [BR:br08330] Gastrointestinal agent DG01975 Agents for peptic ulcer DG01646 Proton pump inhibitor (PPI) DG00020 Omeprazole Metabolizing enzyme substrate DG01639 CYP2C19 substrate DG00020 Omeprazole DG01633 CYP3A/CYP3A4 substrate DG02913 CYP3A4 substrate DG00020 Omeprazole | ||||||||||||
| Other DBs |
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| KCF data | ATOM 24 1 C8x C 14.6300 -20.7200 2 C8y C 14.6300 -22.1200 3 C8x C 15.8424 -22.8200 4 C8y C 17.0549 -22.1200 5 C8y C 17.0549 -20.7200 6 C8x C 15.8424 -20.0200 7 N5x N 18.3864 -22.5526 8 C8y C 19.2093 -21.4200 9 N4x N 18.3864 -20.2874 10 S4a S 20.5800 -21.4200 11 O2a O 13.4176 -22.8200 12 C1a C 12.2221 -22.1296 13 C1b C 21.2800 -22.6324 14 O3c O 21.2800 -20.2076 15 C8y C 22.6798 -22.6324 16 C8y C 23.3703 -23.8280 17 C8y C 24.7703 -23.8278 18 C8y C 25.4701 -22.6153 19 C8x C 24.7797 -21.4198 20 N5x N 23.3797 -21.4199 21 C1a C 26.8800 -22.6152 22 O2a O 25.4610 -25.0232 23 C1a C 26.8796 -25.0232 24 C1a C 22.6849 -25.0152 BOND 26 1 1 2 2 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 2 6 1 6 1 7 4 7 1 8 7 8 2 9 8 9 1 10 5 9 1 11 8 10 1 12 2 11 1 13 11 12 1 14 10 13 1 15 10 14 2 16 13 15 1 17 15 16 2 18 16 17 1 19 17 18 2 20 18 19 1 21 19 20 2 22 15 20 1 23 18 21 1 24 17 22 1 25 22 23 1 26 16 24 1 |