Primidone

Entry

D00474                      Drug

Name

Primidone (JP18/USP/INN);
Mysoline (TN)

Product

MYSOLINE (Bausch Health US)

Generic

PRIMIDONE (A-S Medication Solutions), PRIMIDONE (A-S Medication Solutions), PRIMIDONE (Actavis Pharma), PRIMIDONE (Advagen Pharma Limited), PRIMIDONE (American Health Packaging), PRIMIDONE (Amneal Pharmaceuticals LLC), PRIMIDONE (Amneal Pharmaceuticals of New York LLC), PRIMIDONE (Aphena Pharma Solutions - Tennessee), PRIMIDONE (Aphena Pharma Solutions - Tennessee), PRIMIDONE (Aphena Pharma Solutions - Tennessee), PRIMIDONE (Aphena Pharma Solutions - Tennessee), PRIMIDONE (Aphena Pharma Solutions - Tennessee), PRIMIDONE (AvKARE), PRIMIDONE (AvPAK), PRIMIDONE (Bryant Ranch Prepack), PRIMIDONE (Bryant Ranch Prepack), PRIMIDONE (Bryant Ranch Prepack), PRIMIDONE (DIRECT RX), PRIMIDONE (Dr. Reddy's Laboratories Limited), PRIMIDONE (Golden State Medical Supply), PRIMIDONE (Lannett Company), PRIMIDONE (Marlex Pharmaceuticals), PRIMIDONE (NCS HealthCare of KY), PRIMIDONE (Oceanside Pharmaceuticals), PRIMIDONE (Oxford Pharmaceuticals), PRIMIDONE (PD-Rx Pharmaceuticals)

Formula

C12H14N2O2

Exact mass

218.1055

Mol weight

218.2518

Structure

Simcomp

Class

Neuropsychiatric agent
DG03199 Antiepileptic agent
DG01904 Barbiturate antiepileptic

Remark

Same as:

C07371

Therapeutic category:

1135

ATC code:

N03AA03

Product:

D00474<JP/US>

Efficacy

Antiepileptic

Comment

Barubiturate derivative
Active form of prodrug: Phenobarbital [DR:D00506], Phenylethylmalonamide [CPD:C07499]

Interaction

Structure map

map07033

Anticonvulsants

map07230

GABA-A receptor agonists/antagonists

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AA Barbiturates and derivatives
     N03AA03 Primidone
      D00474  Primidone (JP18/USP/INN) <JP/US>
USP drug classification [BR:br08302]
Anticonvulsants
  Gamma-aminobutyric Acid (GABA) Augmenting Agents
   Barbituates
    Primidone
     D00474  Primidone (JP18/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1135  Primidones
     D00474  Primidone (JP18/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
  DG03199  Antiepileptic agent
   DG01904  Barbiturate antiepileptic
    D00474  Primidone
Drug classes [BR:br08332]
Neuropsychiatric agent
  DG03199  Antiepileptic agent
   D00474  Primidone
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
  D00474  Primidone
Prodrugs [br08324.html]
D00474

Other DBs

CAS:

125-33-7

PubChem:

7847540

ChEBI:

8412

LigandBox:

D00474

NIKKAJI:

J3.260C

KCF data

ATOM        16
            1   C1z C    22.4914  -18.6613
            2   C8y C    23.6964  -17.9536
            3   C5x C    21.2571  -17.9768
            4   C5x C    22.4914  -20.0653
            5   C1b C    23.6964  -19.3574
            6   C8x C    24.9073  -18.6379
            7   C8x C    23.7489  -16.5496
            8   N1x N    20.0522  -18.6613
            9   O5x O    21.2571  -16.5554
            10  N1x N    21.2571  -20.7673
            11  O5x O    23.6847  -20.7673
            12  C1a C    25.0946  -19.3574
            13  C8x C    26.1124  -17.9302
            14  C8x C    24.8839  -15.8417
            15  C1x C    20.0522  -20.0653
            16  C8x C    26.1007  -16.5320
BOND        17
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 2
            6     2   7 1
            7     3   8 1
            8     3   9 2
            9     4  10 1
            10    4  11 2
            11    5  12 1
            12    6  13 1
            13    7  14 2
            14    8  15 1
            15   13  16 2
            16   10  15 1
            17   14  16 1