Penicillamine


Entry
D00496                      Drug                                   
Name
Penicillamine (JAN/USP/INN);
Cuprimine (TN);
Depen (TN)
Product
CUPRIMINE (Bausch Health US), DEPEN (Meda Pharmaceuticals)
  Generic
PENICILLAMINE (ANI Pharmaceuticals), PENICILLAMINE (Actavis Pharma), PENICILLAMINE (Apotex Corp.), PENICILLAMINE (Breckenridge Pharmaceutical), PENICILLAMINE (Dr. Reddy's Laboratories), PENICILLAMINE (Granules Pharmaceuticals), PENICILLAMINE (Lupin Pharmaceuticals), PENICILLAMINE (Navinta LLC), PENICILLAMINE (Oceanside Pharmaceuticals), PENICILLAMINE (Par Pharmaceutical), PENICILLAMINE (Par Pharmaceutical), PENICILLAMINE (Proficient Rx LP)
Formula
C5H11NO2S
Exact mass
149.051
Mol weight
149.2113
Structure
Simcomp
Class
Anti-inflammatory
 DG01985  Disease modifying anti-rheumatic drug (DMARD)
Vitamin and mineral
 DG01692  Chelator
Remark
Same as: C07418
Therapeutic category: 3929 4430
ATC code: M01CC01
Chemical structure group: DG00763
Product (DG00763): D00496<JP/US>
Efficacy
Antidote, Antirheumatic, Chelating agent
  Disease
Wilson's disease [DS:H00210]
Interaction
Structure map
map07050  Antirheumatics - DMARDs and biological agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
   M01C SPECIFIC ANTIRHEUMATIC AGENTS
    M01CC Penicillamine and similar agents
     M01CC01 Penicillamine
      D00496  Penicillamine (JAN/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Electrolytes/Minerals/Metals/Vitamins
  Electrolyte/Mineral/Metal Modifiers
   Penicillamine
    D00496  Penicillamine (JAN/USP/INN)
 Genitourinary Agents
  Genitourinary Agents, Other
   Penicillamine
    D00496  Penicillamine (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   392  Antidotes
    3929  Others
     D00496  Penicillamine (JAN/USP/INN)
 4  Agents affecting cellular function
  44  Allergic agents
   443  Nonspecific immunogen preparations
    4430  Nonspecific immunogen preparations
     D00496  Penicillamine (JAN/USP/INN)
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01985  Disease modifying anti-rheumatic drug (DMARD)
   DG00763  Penicillamine
    D00496  Penicillamine
 Vitamin and mineral
  DG01692  Chelator
   DG00763  Penicillamine
    D00496  Penicillamine
Drug classes [BR:br08332]
 Antirheumatic agent
  DG01985  Disease modifying anti-rheumatic drug (DMARD)
   D00496  Penicillamine
Drug groups [BR:br08330]
 Anti-inflammatory
  DG01985  Disease modifying anti-rheumatic drug (DMARD)
   DG00763  Penicillamine
 Vitamin and mineral
  DG01692  Chelator
   DG00763  Penicillamine
Other DBs
CAS: 52-67-5
PubChem: 7847562
ChEBI: 7959
PDB-CCD: LEI[PDBj]
LigandBox: D00496
NIKKAJI: J9.116B
KCF data

ATOM        9
            1   C6a C    10.5700  -21.9100
            2   C1c C    11.7824  -22.6100
            3   O6a O     9.3576  -22.6100
            4   O6a O    10.5700  -20.5100
            5   C1d C    12.9779  -21.9196
            6   S1a S    14.1653  -22.6051
            7   N1a N    11.7825  -24.0098
            8   C1a C    12.9780  -20.5103
            9   C1a C    14.1904  -21.2196
BOND        8
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     5   6 1
            6     2   7 1 #Up
            7     5   8 1
            8     5   9 1