Entry

D00547                      Drug

Name

Sevoflurane (JP18/USAN/INN);
Ultane (TN)

Product

ULTANE (AbbVie), ULTANE (AbbVie)

Generic

SEVOFLURANE (Baxter Healthcare Corporation), SEVOFLURANE (Baxter Healthcare Corporation), SEVOFLURANE (Halocarbon Life Sciences), SEVOFLURANE (Piramal Critical Care), SEVOFLURANE (Piramal Critical Care), SOJOURN (Piramal Critical Care), SEVOFLURANE (Sandoz)

Formula

C4H3F7O

Exact mass

200.0072

Mol weight

200.0548

Structure

Simcomp

Class

Neuropsychiatric agent
DG02030  Anesthetics
  DG02027  General anesthetics
   DG02028  Inhalational anaesthetics
    DG01994  Halogenated hydrocarbons

Remark

Same as:

C07520

Therapeutic category:

1119

ATC code:

N01AB08

Product:

D00547<JP/US>

Efficacy

Anesthetic (inhalation)

Comment

Halogenated alkane derivative

Interaction

Brite

Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
  N01 ANESTHETICS
   N01A ANESTHETICS, GENERAL
    N01AB Halogenated hydrocarbons
     N01AB08 Sevoflurane
      D00547  Sevoflurane (JP18/USAN/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   111  General anesthetics
    1119  Others
     D00547  Sevoflurane (JP18/USAN/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
  DG02030  Anesthetics
   DG02027  General anesthetics
    DG02028  Inhalational anaesthetics
     DG01994  Halogenated hydrocarbons
      D00547  Sevoflurane
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
  D00547  Sevoflurane
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
  D00547

Other DBs

CAS:	28523-86-6

PubChem:

7847613

ChEBI:

9130

LigandBox:

D00547

NIKKAJI:

J20.100F

KCF data

ATOM        12
            1   C1c C    23.0068  -17.6046
            2   C1d C    23.0068  -15.9970
            3   C1d C    21.7955  -18.3094
            4   O2a O    24.2123  -18.3094
            5   X   F    22.9951  -14.5993
            6   X   F    24.3988  -15.9970
            7   X   F    21.5973  -16.0611
            8   X   F    20.5723  -18.9908
            9   X   F    21.0790  -17.0865
            10  X   F    22.4768  -19.5150
            11  C1b C    25.4238  -17.6046
            12  X   F    26.6351  -18.3094
BOND        11
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     2   7 1
            7     3   8 1
            8     3   9 1
            9     3  10 1
            10    4  11 1
            11   11  12 1