| Entry |
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| Name | Warfarin sodium (USP); Coumadin (TN); Jantoven (TN) | ||||||||||
| Product | COUMADIN (Cardinal Health) | ||||||||||
| Generic | WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (Amneal Pharmaceuticals LLC), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Denton Pharma), WARFARIN SODIUM (Denton Pharma), WARFARIN SODIUM (Denton Pharma), WARFARIN SODIUM (Denton Pharma), WARFARIN SODIUM (Exelan Pharmaceuticals), WARFARIN SODIUM (Golden State Medical Supply), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (American Health Packaging), WARFARIN SODIUM (American Health Packaging), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Cadila Healthcare Limited), WARFARIN SODIUM (Cardinal Health), WARFARIN SODIUM (Cardinal Health), WARFARIN SODIUM (Clinical Solutions Wholesale), WARFARIN SODIUM (DIRECT RX), WARFARIN SODIUM (Denton Pharma), WARFARIN SODIUM (Denton Pharma), WARFARIN SODIUM (Denton Pharma), WARFARIN SODIUM (Golden State Medical Supply), WARFARIN SODIUM (NuCare Pharmaceuticals), WARFARIN SODIUM (NuCare Pharmaceuticals), WARFARIN SODIUM (NuCare Pharmaceuticals), WARFARIN SODIUM (NuCare Pharmaceuticals), WARFARIN SODIUM (NuCare Pharmaceuticals), WARFARIN SODIUM (NuCare Pharmaceuticals), WARFARIN SODIUM (PD-Rx Pharmaceuticals), WARFARIN SODIUM (Preferred Pharmaceuticals), WARFARIN SODIUM (Preferred Pharmaceuticals), WARFARIN SODIUM (Preferred Pharmaceuticals), WARFARIN SODIUM (Proficient Rx LP), WARFARIN SODIUM (Proficient Rx LP), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (RedPharm Drug), WARFARIN SODIUM (Rising Health), WARFARIN SODIUM (Taro Pharmaceuticals U.S.A.), WARFARIN SODIUM (Teva Pharmaceuticals USA), JANTOVEN (Upsher-Smith Laboratories), WARFARIN SODIUM (Zydus Pharmaceuticals (USA)) | ||||||||||
| Formula | C19H15O4. Na | ||||||||||
| Exact mass | 330.0868 | ||||||||||
| Mol weight | 330.3098 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Blood modifier agent DG01950 Antithrombotic agent DG01708 Coumarin anticoagulant DG01760 Warfarin and analog Metabolizing enzyme substrate DG01642 CYP2C9 substrate | ||||||||||
| Remark |
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| Efficacy | Anticoagulant, Vitamin K antagonist | ||||||||||
| Comment | coumarin derivative | ||||||||||
| Target | VKORC1 [HSA:79001] [KO:K05357] NQO1 [HSA:1728] [KO:K00355] | ||||||||||
| Pathway |
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| Metabolism | Enzyme: CYP2C9 [HSA:1559] | ||||||||||
| Interaction | |||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] B BLOOD AND BLOOD FORMING ORGANS B01 ANTITHROMBOTIC AGENTS B01A ANTITHROMBOTIC AGENTS B01AA Vitamin K antagonists B01AA03 Warfarin D00564 Warfarin sodium (USP) <US> USP drug classification [BR:br08302] Blood Products and Modifiers Anticoagulants Vitamin K Antagonist Warfarin D00564 Warfarin sodium (USP) Drug groups [BR:br08330] Blood modifier agent DG01950 Antithrombotic agent DG01708 Coumarin anticoagulant DG01760 Warfarin and analog DG00149 Warfarin D00564 Warfarin sodium Metabolizing enzyme substrate DG01642 CYP2C9 substrate DG00149 Warfarin D00564 Warfarin sodium Target-based classification of drugs [BR:br08310] Enzymes Oxidoreductases (EC1) NAD(P)H dehydrogenase NQO1 D00564 Warfarin sodium (USP) <US> Vitamin-K-epoxide reductase VKORC1 D00564 Warfarin sodium (USP) <US> Drug metabolizing enzymes and transporters [br08309.html] Drug metabolizing enzymes D00564 Pharmacogenomic biomarkers [br08341.html] Polymorphisms and mutations affecting drug response D00564 Drug groups [BR:br08330] Blood modifier agent DG01950 Antithrombotic agent DG01708 Coumarin anticoagulant DG01760 Warfarin and analog DG00149 Warfarin Metabolizing enzyme substrate DG01642 CYP2C9 substrate DG00149 Warfarin | ||||||||||
| Other DBs |
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| KCF data | ATOM 24 1 C8y C 24.8370 -17.3313 2 C1c C 26.0487 -18.0418 3 C8y C 23.6253 -18.0245 4 C8y C 24.8428 -15.9389 5 C1b C 27.2662 -17.3429 6 C8y C 22.4252 -17.3137 7 O1a O 23.6894 -19.4226 #- 8 O7x O 23.6427 -15.2398 9 O6a O 26.0661 -15.2515 10 C5a C 28.4721 -18.0534 11 C8y C 22.4311 -15.9215 12 C8x C 21.2135 -18.0245 13 C1a C 28.4662 -19.4576 14 O5a O 29.6837 -17.3604 15 C8x C 21.2193 -15.2224 16 C8x C 20.0077 -17.3196 17 C8x C 20.0077 -15.9156 18 C8y C 26.0423 -19.4449 19 C8x C 24.8108 -20.1486 20 C8x C 24.8046 -21.5475 21 C8x C 26.0129 -22.2524 22 C8x C 27.2445 -21.5486 23 C8x C 27.2507 -20.1497 24 Z Na 21.3600 -19.4568 #+ BOND 25 1 1 2 1 2 1 3 2 3 1 4 1 4 2 5 1 5 3 6 1 6 3 7 1 7 4 8 1 8 4 9 2 9 5 10 1 10 6 11 2 11 6 12 1 12 10 13 1 13 10 14 2 14 11 15 1 15 12 16 2 16 15 17 2 17 8 11 1 18 16 17 1 19 2 18 1 20 18 19 2 21 19 20 1 22 20 21 2 23 21 22 1 24 22 23 2 25 18 23 1 |