| Entry |
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Name | Telmisartan (JP18/USP/INN); Micardis (TN) | ||||||||||||
| Product | MICARDIS (Boehringer Ingelheim Pharmaceuticals) | ||||||||||||
| Generic | TELMISARTAN (A-S Medication Solutions), TELMISARTAN (A-S Medication Solutions), TELMISARTAN (A-S Medication Solutions), TELMISARTAN (Alembic Pharmaceuticals), TELMISARTAN (Alembic Pharmaceuticals Limited), TELMISARTAN (Amneal Pharmaceuticals LLC), TELMISARTAN (Amneal Pharmaceuticals of New York LLC), TELMISARTAN (Ascend Laboratories), TELMISARTAN (Aurobindo Pharma Limited), TELMISARTAN (AvKARE), TELMISARTAN (Bryant Ranch Prepack), TELMISARTAN (Bryant Ranch Prepack), TELMISARTAN (Bryant Ranch Prepack), TELMISARTAN (Bryant Ranch Prepack), TELMISARTAN (Bryant Ranch Prepack), TELMISARTAN (Bryant Ranch Prepack), TELMISARTAN (CELLTRION USA), TELMISARTAN (Cadila Healthcare Limited), TELMISARTAN (Cadila Pharmaceuticals Limited), TELMISARTAN (Camber Pharmaceuticals), TELMISARTAN (Glenmark Pharmaceuticals), TELMISARTAN (Micro Labs Limited), TELMISARTAN (Modavar Pharmaceuticals LLC), TELMISARTAN (Mylan Pharmaceuticals), TELMISARTAN (NuCare Pharmaceuticals), TELMISARTAN (NuCare Pharmaceuticals), TELMISARTAN (NuCare Pharmaceuticals), TELMISARTAN (Proficient Rx LP), TELMISARTAN (REMEDYREPACK), TELMISARTAN (REMEDYREPACK), TELMISARTAN (Sandoz), TELMISARTAN (Solco Healthcare US), TELMISARTAN (Torrent Pharmaceuticals Limited), TELMISARTAN (Zydus Pharmaceuticals (USA)), TELMISARTAN (medsource pharmaceuticals) | ||||||||||||
| Formula | C33H30N4O2 | ||||||||||||
| Exact mass | 514.2369 | ||||||||||||
| Mol weight | 514.6169 | ||||||||||||
| Structure |  | ||||||||||||
| Simcomp | |||||||||||||
| Class | Cardiovascular agent DG01925 Renin-angiotensin system inhibitor DG01495 Angiotensin II receptor antagonist DG03231 Antihypertensive DG01495 Angiotensin II receptor antagonist Metabolizing enzyme substrate DG02924 UGT substrate | ||||||||||||
| Remark |
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| Efficacy | Antihypertensive, Angiotensin II receptor antagonist | ||||||||||||
| Disease | Hypertension [DS:H01633] | ||||||||||||
| Target | AGTR1 [HSA:185] [KO:K04166] | ||||||||||||
| Pathway |
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| Metabolism | Enzyme: UGT [KO:K00699] | ||||||||||||
| Interaction | |||||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] C CARDIOVASCULAR SYSTEM C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM C09C ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), PLAIN C09CA Angiotensin II receptor blockers, plain C09CA07 Telmisartan D00627 Telmisartan (JP18/USP/INN) <JP/US> USP drug classification [BR:br08302] Cardiovascular Agents Angiotensin II Receptor Antagonists Telmisartan D00627 Telmisartan (JP18/USP/INN) Therapeutic category of drugs in Japan [BR:br08301] 2 Agents affecting individual organs 21 Cardiovascular agents 214 Antihypertensives 2149 Others D00627 Telmisartan (JP18/USP/INN) Drug groups [BR:br08330] Cardiovascular agent DG01925 Renin-angiotensin system inhibitor DG01495 Angiotensin II receptor antagonist D00627 Telmisartan DG03231 Antihypertensive DG01495 Angiotensin II receptor antagonist D00627 Telmisartan Metabolizing enzyme substrate DG02924 UGT substrate D00627 Telmisartan Drug classes [BR:br08332] Cardiovascular agent DG01495 Angiotensin II receptor antagonist D00627 Telmisartan DG03231 Antihypertensive D00627 Telmisartan Target-based classification of drugs [BR:br08310] G Protein-coupled receptors Rhodopsin family Angiotensin AGTR1 D00627 Telmisartan (JP18/USP/INN) <JP/US> Drugs listed in the Japanese Pharmacopoeia [BR:br08311] Chemicals D00627 Telmisartan D00627 Telmisartan tablets New drug approvals in Europe [br08329.html] European public assessment reports (EPAR) authorised medicine D00627 New drug approvals in Japan [br08318.html] Drugs with new active ingredients D00627 Drug metabolizing enzymes and transporters [br08309.html] Drug metabolizing enzymes D00627 | ||||||||||||
| Other DBs |
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| KCF data | ATOM 39 1 C8x C 6.3000 -7.3500 2 C8x C 6.3000 -8.7500 3 C8x C 7.5124 -9.4500 4 C8x C 8.7249 -8.7500 5 C8y C 8.7249 -7.3500 6 C8y C 7.5124 -6.6500 7 C8y C 9.9560 -6.6390 8 C8x C 11.1612 -7.3347 9 C8x C 12.3735 -6.6346 10 C8y C 12.3735 -5.2346 11 C8x C 11.1683 -4.5389 12 C8x C 9.9559 -5.2390 13 C6a C 7.5124 -5.2502 14 O6a O 6.2832 -4.5403 15 O6a O 8.7080 -4.5598 16 C1b C 13.5914 -4.5312 17 N4y N 14.8034 -5.2307 18 C8y C 15.2226 -6.5648 19 C8y C 16.6225 -6.5780 20 N5x N 17.0677 -5.2506 21 C8y C 15.9428 -4.4171 22 C1b C 15.9551 -3.0100 23 C1b C 17.1773 -2.3185 24 C1a C 18.3595 -3.0151 25 C8x C 14.5112 -7.7706 26 C8y C 15.1998 -9.0596 27 C8x C 16.5998 -9.0027 28 C8y C 17.3111 -7.7969 29 C1a C 18.6894 -7.7394 30 C8y C 14.5146 -10.2563 31 N4y N 13.1146 -10.2563 32 C1a C 12.4229 -9.0592 33 C8y C 12.6819 -11.5878 34 C8y C 13.8146 -12.4107 35 N5x N 14.9472 -11.5878 36 C8x C 13.8146 -13.8107 37 C8x C 12.5931 -14.5162 38 C8x C 11.3745 -13.8131 39 C8x C 11.3745 -12.3904 BOND 44 1 1 2 2 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 2 6 1 6 1 7 5 7 1 8 7 8 2 9 8 9 1 10 9 10 2 11 10 11 1 12 11 12 2 13 7 12 1 14 6 13 1 15 13 14 2 16 13 15 1 17 10 16 1 18 16 17 1 19 17 18 1 20 18 19 1 21 19 20 1 22 20 21 2 23 17 21 1 24 21 22 1 25 22 23 1 26 23 24 1 27 18 25 2 28 25 26 1 29 26 27 2 30 27 28 1 31 19 28 2 32 28 29 1 33 26 30 1 34 30 31 1 35 31 32 1 36 31 33 1 37 33 34 2 38 34 35 1 39 30 35 2 40 34 36 1 41 36 37 2 42 37 38 1 43 38 39 2 44 39 33 1 |