| Entry |
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| Name | Dibucaine (USP); Cinchocaine (INN); Nupercaine (TN) | ||||||||||
| Formula | C20H29N3O2 | ||||||||||
| Exact mass | 343.226 | ||||||||||
| Mol weight | 343.4632 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Neuropsychiatric agent DG02030 Anesthetics DG01675 Local anesthetic DG01673 Amide type local anesthetic | ||||||||||
| Remark |
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| Efficacy | Anesthetic (local) | ||||||||||
| Target | SCN1A [HSA:6323] [KO:K04833] SCN2A [HSA:6326] [KO:K04834] SCN3A [HSA:6328] [KO:K04836] SCN4A [HSA:6329] [KO:K04837] SCN5A [HSA:6331] [KO:K04838] SCN8A [HSA:6334] [KO:K04840] SCN9A [HSA:6335] [KO:K04841] SCN10A [HSA:6336] [KO:K04842] SCN11A [HSA:11280] [KO:K04843] | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] C CARDIOVASCULAR SYSTEM C05 VASOPROTECTIVES C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE C05AD Local anesthetics C05AD04 Cinchocaine D00733 Dibucaine (USP) D DERMATOLOGICALS D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC. D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC. D04AB Anesthetics for topical use D04AB02 Cinchocaine D00733 Dibucaine (USP) N NERVOUS SYSTEM N01 ANESTHETICS N01B ANESTHETICS, LOCAL N01BB Amides N01BB06 Cinchocaine D00733 Dibucaine (USP) S SENSORY ORGANS S01 OPHTHALMOLOGICALS S01H LOCAL ANESTHETICS S01HA Local anesthetics S01HA06 Cinchocaine D00733 Dibucaine (USP) S02 OTOLOGICALS S02D OTHER OTOLOGICALS S02DA Analgesics and anesthetics S02DA04 Cinchocaine D00733 Dibucaine (USP) Classification of Japanese OTC drugs [BR:br08313] Agents for urogenital organs and anus 30 Hemorrhoid drugs for external use D00733 Dibucaine (USP) Risk category of Japanese OTC drugs [BR:br08312] Second-class OTC drugs Inorganic and organic chemicals Dibucaine D00733 Dibucaine (USP) Drug groups [BR:br08330] Neuropsychiatric agent DG02030 Anesthetics DG01675 Local anesthetic DG01673 Amide type local anesthetic DG00297 Dibucaine D00733 Dibucaine Target-based classification of drugs [BR:br08310] Ion channels Voltage-gated ion channels Sodium channels SCN1A D00733 Dibucaine (USP) SCN2A D00733 Dibucaine (USP) SCN3A D00733 Dibucaine (USP) SCN4A D00733 Dibucaine (USP) SCN5A D00733 Dibucaine (USP) SCN8A D00733 Dibucaine (USP) SCN9A D00733 Dibucaine (USP) SCN10A D00733 Dibucaine (USP) SCN11A D00733 Dibucaine (USP) Drug groups [BR:br08330] Neuropsychiatric agent DG02030 Anesthetics DG01675 Local anesthetic DG01673 Amide type local anesthetic DG00297 Dibucaine | ||||||||||
| Other DBs |
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| KCF data | ATOM 25 1 C8x C 5.5300 -17.6400 2 C8x C 5.5300 -19.0400 3 C8x C 6.7424 -19.7400 4 C8y C 7.9549 -19.0400 5 C8y C 7.9549 -17.6400 6 C8x C 6.7424 -16.9400 7 N5x N 9.1673 -19.7400 8 C8y C 10.3797 -19.0400 9 C8x C 10.3797 -17.6400 10 C8y C 9.1673 -16.9400 11 O2a O 11.5773 -19.7315 12 C5a C 9.1673 -15.5400 13 N1b N 10.3818 -14.8388 14 C1b C 11.5783 -15.5298 15 C1b C 12.7651 -14.8446 16 N1c N 13.9566 -15.5328 17 O5a O 7.9569 -14.8412 18 C1b C 15.1460 -14.8461 19 C1b C 13.9566 -16.9397 20 C1a C 15.1490 -17.6284 21 C1a C 16.3362 -15.5335 22 C1b C 12.7656 -19.0455 23 C1b C 13.9564 -19.7331 24 C1b C 15.1460 -19.0463 25 C1a C 16.3361 -19.7335 BOND 26 1 1 2 2 2 2 3 1 3 3 4 2 4 4 5 1 5 5 6 2 6 1 6 1 7 4 7 1 8 7 8 2 9 8 9 1 10 9 10 2 11 5 10 1 12 8 11 1 13 10 12 1 14 12 13 1 15 13 14 1 16 14 15 1 17 15 16 1 18 12 17 2 19 16 18 1 20 16 19 1 21 19 20 1 22 18 21 1 23 11 22 1 24 22 23 1 25 23 24 1 26 24 25 1 |