| Entry |
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Name | Rocuronium bromide (JAN/USP/INN); Zemuron (TN) | ||||||||||
| Product | |||||||||||
| Generic | ROCURONIUM (Piramal Critical Care), ROCURONIUM BROMIDE (Almaject), ROCURONIUM BROMIDE (Athenex Pharmaceutical Division), ROCURONIUM BROMIDE (AuroMedics Pharma LLC), ROCURONIUM BROMIDE (Baxter Healthcare Corporation), ROCURONIUM BROMIDE (Civica), ROCURONIUM (Fresenius Kabi USA), ROCURONIUM (Fresenius Kabi USA), ROCURONIUM BROMIDE (Gland Pharma Limited), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (HF Acquisition Co LLC), ROCURONIUM BROMIDE (Hikma Pharmaceuticals USA), ROCURONIUM BROMIDE (Hospira), ROCURONIUM BROMIDE (Hospira), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Medical Purchasing Solutions), ROCURONIUM BROMIDE (Mylan Institutional LLC), ROCURONIUM (Phlow Corporation), ROCURONIUM BROMIDE (Sagent Pharmaceuticals), ROCURONIUM BROMIDE (Sandoz), ROCURONIUM BROMIDE (Solco Healthcare US), ROCURONIUM BROMIDE (XGen Pharmaceuticals DJB) | ||||||||||
| Formula | C32H53N2O4. Br | ||||||||||
| Exact mass | 608.3189 | ||||||||||
| Mol weight | 609.6782 | ||||||||||
| Structure |  | ||||||||||
| Simcomp | |||||||||||
| Class | Musculo-skeletal system agent DG02029 Muscle relaxant DG01696 Peripherally-acting muscle relaxant DG03117 Nondepolarizing neuromuscular blocking agent DG01742 Quaternary ammonium compound type muscle relaxant | ||||||||||
| Remark |
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| Efficacy | Skeletal muscle relaxant, Neuromuscular blocking agent, Muscarinic acetylcholine receptor antagonist | ||||||||||
| Comment | Quaternary ammonium compound | ||||||||||
| Target | CHRN (neuronal type) [HSA:1135 1136 1137 1138 8973 1139 55584 57053 1141 1142 1143] [KO:K04804 K04805 K04806 K04807 K04808 K04809 K04810 K04811 K04813 K04814 K04815] CHRM [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133] | ||||||||||
| Pathway |
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| Interaction | |||||||||||
| Structure map |
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| Brite | Anatomical Therapeutic Chemical (ATC) classification [BR:br08303] M MUSCULO-SKELETAL SYSTEM M03 MUSCLE RELAXANTS M03A MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS M03AC Other quaternary ammonium compounds M03AC09 Rocuronium bromide D00765 Rocuronium bromide (JAN/USP/INN) <JP/US> Therapeutic category of drugs in Japan [BR:br08301] 1 Agents affecting nervous system and sensory organs 12 Agents affecting peripheral nervous system 122 Skeletal muscle relaxants 1229 Others D00765 Rocuronium bromide (JAN/USP/INN) Drug groups [BR:br08330] Musculo-skeletal system agent DG02029 Muscle relaxant DG01696 Peripherally-acting muscle relaxant DG03117 Nondepolarizing neuromuscular blocking agent D00765 Rocuronium bromide DG01742 Quaternary ammonium compound type muscle relaxant D00765 Rocuronium bromide Target-based classification of drugs [BR:br08310] G Protein-coupled receptors Rhodopsin family Acetylcholine (muscarinic) CHRM D00765 Rocuronium bromide (JAN/USP/INN) <JP/US> Ion channels Ligand-gated ion channels Acetylcholine (nicotinic) CHRN (neuronal type) D00765 Rocuronium bromide (JAN/USP/INN) <JP/US> New drug approvals in Japan [br08318.html] Drugs with new active ingredients D00765 | ||||||||||
| Other DBs |
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| KCF data | ATOM 39 1 C1y C 7.4200 -8.9600 2 C1y C 7.4200 -10.3600 3 C1x C 8.6324 -11.0600 4 C1y C 9.8449 -10.3600 5 C1z C 9.8449 -8.9600 6 C1x C 8.6324 -8.2600 7 C1x C 11.0573 -11.0600 8 C1x C 12.2697 -10.3600 9 C1y C 12.2697 -8.9600 10 C1y C 11.0573 -8.2600 11 C1y C 13.4822 -8.2600 12 C1z C 13.4822 -6.8600 13 C1x C 12.2697 -6.1600 14 C1x C 11.0573 -6.8600 15 C1x C 15.9070 -8.2600 16 C1y C 15.9070 -6.8600 17 C1y C 14.6946 -6.1600 18 O1a O 6.2076 -11.0600 19 N1y N 6.2076 -8.2600 20 C1a C 9.8449 -7.5600 21 C1a C 13.4822 -5.4600 22 N2y N 17.1066 -6.1673 #+ 23 O7a O 14.6946 -4.4100 24 C1x C 17.1066 -4.7673 25 C7a C 13.4862 -3.7123 26 C1a C 12.2927 -4.4016 27 O6a O 13.4861 -2.3102 28 C1x C 18.4381 -6.5999 29 C1x C 19.2610 -5.4673 30 C1x C 18.4381 -4.3347 31 C1b C 17.1066 -7.5673 32 C2b C 18.2959 -8.2540 33 C2a C 18.2960 -9.6598 34 C1x C 6.2076 -6.8602 35 C1x C 4.9951 -6.1602 36 O2x O 3.7827 -6.8602 37 C1x C 3.7827 -8.2600 38 C1x C 4.9951 -8.9600 39 X Br 16.8700 -3.0100 #- BOND 43 1 1 2 1 2 2 3 1 3 3 4 1 4 4 5 1 5 5 6 1 6 1 6 1 7 4 7 1 8 7 8 1 9 8 9 1 10 9 10 1 11 5 10 1 12 9 11 1 13 11 12 1 14 12 13 1 15 13 14 1 16 10 14 1 17 11 15 1 18 15 16 1 19 16 17 1 20 12 17 1 21 2 18 1 #Down 22 1 19 1 #Up 23 5 20 1 #Up 24 12 21 1 #Up 25 16 22 1 #Up 26 17 23 1 #Up 27 22 24 1 28 23 25 1 29 25 26 1 30 25 27 2 31 22 28 1 32 28 29 1 33 29 30 1 34 24 30 1 35 22 31 1 36 31 32 1 37 32 33 2 38 19 34 1 39 34 35 1 40 35 36 1 41 36 37 1 42 37 38 1 43 19 38 1 |